Exam 4 Flashcards
Cardiomyopathy
primary disease of the myocardium excluding myocardial dysfunction due to ischemia or chronic valvular disease
Dilated Cardiomyopathy
all four chambers are enlarged with impaired systolic function of both the LV and RV due to a wide range of underlying causes
Hypertrophic Cardiomyopathy
an autosomal dominant inherited disease of the myocardium related to abnormalities in gene coding for contractile proteins
Restrictive Cardiomyopathy
fibrotic stiff ventricles due to altered myocardium with significantly impaired diastolic function
Causes and symptoms of Dilated Cardiomyopathy
Causes: idiopathic, infections, toxins, metabolic, inherited, Tako-tsubo, autoimmune/systemic inflammatory disease
Symptoms: Dyspnea, orthopnea, DOE, cough, rales, crackles, sputum
Causes and symptoms of Hypertrophic Cardiomyopathy
Causes: inherited
Symptoms: angina, syncope, DOE, Paroxysmal Nocturnal Dyspnea, pulmonary edema
Causes and symptoms of Restrictive Cardiomyopathy
Causes: infiltrative, deposition or scarring to organs, endomyocardial fibrosis, myocardial fibrosis
Symptoms: heart failure due to impaired diastolic filling and inability to maintain cardiac output
5 parameters of Diastolic Algorithm
- Average E/e’ > 14
- Septal e’ velocity < 7 cm/s
- Lateral e’ velocity < 10 cm/s
- TR velocity > 2.8 m/s
- LA volume index > 34 ml/m^2
E/A ratio for Grades 1, 2, and 3
Grade 1: E/A ≤ 0.8 and E ≤ 50 cm/s
Grade 2: E/A ≤ 0.8 and E > 50 cm/s OR E/A > 0.8 - < 2
Grade 3: ≥ 2
Additional Parameters of Diastolic Dysfunction:
Normal
DT: 160-200 ms
E/e’: ≤ 14
AR-A: < 0 ms
IVRT: 50-100 ms
PVA: ≤ 35 cm/s
S~D
L Wave: < 20 cm/s
Propagation Velocity: > 50 cm/s
Additional Parameters of Diastolic Dysfunction:
Grade 1
DT: > 200ms
E/e’: increasing ratio implies worsening
AR-A: < 0 ms
IVRT: > 100 ms
PVA: ≤ 35 cm/s
S significantly > D
L Wave: > 20 cm/s
Propagation Velocity: decreasing slope implies worsening
Additional Parameters of Diastolic Dysfunction:
Grade 2
DT: 160-200 ms
E/e’: increasing ratio implies worsening
AR-A: ≥ 30 ms
IVRT: 50-100 ms
PVA: > 35 cm/s
S<D
L Wave: > 20 cm/s
Propagation Velocity: decreasing slope implies worsening
Additional Parameters of Diastolic Dysfunction:
Grade 3
DT: < 160 ms
E/e’: increasing ratio implies worsening
AR-A: ≥ 30 ms
IVRT: < 50 ms
PVA: > 35 cm/s
S significantly < D
L Wave: > 20 cm/s
Propagation Velocity: decreasing slope implies worsening
DD and age
~ 60 E/A ratio = 1
> 60 E/A ratio = < 1
> 60 increased decel time and IVRT
> 50 S > D
Valsalva and DD
valsalva can convert restrictive LV inflow to a pseudonormal