Exam 4 Flashcards
Tissue
organized mass of similar cells with a specific function
The tissue consists of:
- Vertebrates
- Cells
- Extracellular Matrix (ECM)
- Cell Junction
Vertebrates: 4 types of tissue
- Epithelium or epithelial tissue
- Connective tissue
- Nerve tissue
- Muscle tissue
Cells
Themselves (covered in their turn)
Extracellular Matrix (ECM)
All material outside of cells but materials made by cells and composed of:
- Fibers
- Ground substance
Fibers
- Collagen
- Elastic FIber
Ground Substance
liquidy -> gel -> granular
- complex macromolecules
- filling in spaces
- lubricants and cushions
- interstitial fluids: blood plasma, lymph fluid
Cell Junctions
Specialized structures that connect cells together
Tight Junctions also include occluding junctions, zonulae occludins
- Seal neighboring epithelial cells together tightly enough to prevent liquids from passing between the cells to get to the underlying tissues.
- Make the epithelial layer water tight
Anchoring Junctions
- adhering junctions: attach cells to each other
- desmosomes: attach cells to each other
- hemidesmosomes: attach cells to the underlying ECM
Tethering filaments
- adherins junction: action
- desmosomes: keratin in epithelial cells, tonofilaments in other tissues
Gap Junctions
“tunnel” shaped protein through the plasma membrane of adjacent cells that allows the passage of water, ions, and other small molecules between cells
connexon (gap junctions)
The tubular protein composed of 6 proteins each called connexin
Epithelium or epithelial tissue
Covers surfaces - forms a continuous layer that covers most body surfaces and cavities:
- classified by cell shape and layering
Simple epithelium
One cell thick
Squamous (epithelial tissue)
flat, tile like
Cuboidal (epithelial tissue)
about as tall as wide
Columnar (epithelial tissue)
taller than wide
Basal lamina (epithelial tissue)
thin sheet of extracellular proteins-lamina: adhesive fibrous protein and sticky ECM
- anchored to the underlying connective tissue
Basement membrane (basal lamina and connective tissue) (epithelial tissue)
not a “cellular” membrane