Exam 3: PollEv Questions

Question 1

Which state would you expect to have a high hydrostatic gradient?
a) normal tissue environment
b) tumor microenvironment

Answer 1

normal tissue environment

Question 2

If you put a human tumor in a mouse will that
help recapitulate a tumor microenvironment?

Answer 2

• helps, but isn’t perfect
• suggests- mice don’t have the exact same ECM proteins, cell receptors, …

Question 3

What molecule do you think is involved in the angiogenic switch?
a.) VEGF (vascular endothelial growth factors)
b.) MMP (matrix metalloproteases)

Answer 3

MMP (matrix metalloproteases)

Question 4

What is the function of the
pancreas?
* A) Make enzymes that help digest the foods we eat.
* B) Makes and releases insulin, which helps lower blood sugar
* C) Makes and releases glucagon, which helps raise blood sugar.
* D) B and C
* E) A, B, and C

Answer 4

E) A, B, and C

Question 5

JC 5: Figure 1.
* Neo-angiogenesis occurs in _____ normal islets, _____ hyperplastic islets, and _____ tumors.
* A) some, some, all
* B) no, all, all
* C) no, all, some
* D) no, some, all

Answer 5

D) no, some, all

Question 6

JC 5: Figure 3.
* Neo-angiogenesis (in vitro) occurs in _____ normal islets, _____ hyperplastic islets, and _____ tumors.
* A) some, some, all
* B) no, all, all
* C) no, all, some
* D) no, some, all

Answer 6

D) no, some, all

Question 7

JC 5: Table 1.
* The frequency of islets that are capable of neo-angiogenesis (in vitro) is similar to the frequency of _________.
* A) tumor formation
* B) hyperplasia formation
* C) B-cell proliferation
* D) insulin production

Answer 7

A) tumor formation