Exam 3 - Poison 1-2 and Toxidromes Flashcards

1
Q

What is the poison help/control center number?

A

1(800)222-1222

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2
Q

When should patients be referred to the hospital? (2)

A

moderate-severe exposures, intentional ingestions

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3
Q

What are the ABCs of poison management? (5)

A

airway, breathing, circulation, dextrose/decontamination, EKG/elimination

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4
Q

What are non-pharmacologic treatments for poisoning? (4)

A

inhalational (removing patient from exposure area), topical/dermal (irrigation with soap and water), ingestions (orogastric lavage), hemodialysis

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5
Q

What pharmacologic therapy should not be used for poisonings?

A

syrup of ipecac

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6
Q

What is the dosing for activated charcoal in poisoning?

A

1 g/kg

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7
Q

What substances will not bind to activated charcoal? (3)

A

ionized metals, alcohols, gasoline

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8
Q

What is added to activated charcoal to improve palatability?

A

sorbitol

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9
Q

What is the dosing for whole bowel irrigation in poisoning?

A

1-2 L/hr PO/NG until rectal effluent clear

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10
Q

How do anticholinergic toxidromes typically present? (4)

A

all vitals slightly elevated, dilated pupils, dry mucous membranes, no bowel sounds

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11
Q

What is the treatment and dosing for an anticholinergic toxidrome?

A

physostigmine, 0.5-2 mg IV

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12
Q

How do sedative-hypnotic toxidromes typically present? (4)

A

otherwise normal vital signs, 4 mm (normal) pupils, normal mucous membranes, bowel sounds present

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13
Q

How do adrenergic/sympathomimetic toxidromes typically present? (5)

A

all vitals slightly elevated, 6 mm reactive pupils, diaphoretic, bowel sounds present, tremor

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14
Q

How do opioid toxidromes typically present? (5)

A

otherwise normal vital signs except RR (low), pinpoint pupils, normal mucous membranes, no bowel sounds, hyporeflexic

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15
Q

How do cholinergic toxidromes typically present? (3)

A

otherwise normal vital signs, pinpoint pupils, SLUDGE

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16
Q

What is the dosing for atropine in cholinergic toxidrome treatment?

A

1 mg IV titrated to effect

17
Q

What is the dosing for pralidoxime (2-PAM) in cholinergic toxidrome treatment? (2)

A

30 mg/kg IV bolus, then 8-10 mg/kg/hr

18
Q

What are the killer B’s? (3)

A

bradycardia, bronchorrhea, bronchospasm

19
Q

What drug does not exhibit a toxidrome?

A

acetaminophen

20
Q

What labs make a difference in the care course of a patient? (6)

A

digoxin, vancomycin, phenytoin, lithium, acetaminophen, aspirin