Exam 3- Pharm Flashcards
Class: Growth Hormone
Name: Somatotropin (Genotropin)
Nursing/ Medical Interventions
Assess baseline Height and weight
Monitor glucose in patients who have diabetes
Route: IM or Sub Q
If antibodies to GH our produced resulting in inactive GH use mecasermin for further treatment
Class: Growth Hormone
Name: Somatotropin (Genotropin)
Adverse effects
Hyperglycemia
glucocorticoids oppose growth
Carpal tunnel syndrome
fatality in Prader-Willi syndrome (PWS)
Class: Growth Hormone Antagonists
Name: Octreotide (Sandostatin)
Nursing/ Medical Interventions
Give without food or at bedtime to minimize GI Issues
Suppresses GH release
Monitor glucose
Route: IM or Sub Q
Class: Growth Hormone Antagonists
Name: Octreotide (Sandostatin)
Adverse effects
Diarrhea
N/V
Antidiuretic Hormone aka desmopressin (DDAVP)
Nursing/ Medical Interventions
Route: most common intranasal
Given for DI
Obtain baseline I&O
Reduce water intake/ monitor water intoxication
assess edema
Monitor electrolytes
Antidiuretic Hormone aka desmopressin (DDAVP)
Adverse effects
Water intoxication
(sleepiness, Headaches)
Convulsions
electrolyte imbalance
Insulin
Short acting (Lispro/aspart)
Intermediate (NPH)
Long (Glargine)
Nursing/ Medical Interventions
Short-acting
Lispro+ Aspart (Only give if you’re eating/ before meal, if given after a meal cut the dose of that according to BS in 1/2)
Intermediate
NPH ( Should never be mixed)
Long-acting
Glargine (Lantus) ( Can be given at bedtime or morning ) Sugar will be highest in the morning right before medication
What are the names of lispro ,aspart, and intermediate
Humalog, NovoLog, NPH or Neutral protamine Hagedorn,
Which is the only insulin given via IV
Regular insulin
Humulin, Novolin
IV (u-100 only)
Insulin
Short acting (Lispro/aspart)
Intermediate (NPH)
Long (Glargine)
Adverse effects
Hypoglycemia: tachycardia, dizziness, sweating (B.S. below 70) - Rapid treatment necessary
Liphohypertrophy (subQ fat deposits from too many insulins injections @ same site
Hypokalemia (insulin promotes uptake of K+ cells = lower levels
Peak and onset of Short-acting, regular, intermediate and long-acting
Know chart
Short-acting
Peak: 1/2 hr -2.5 hr
Onset: 15-30 min
Regular
Peak: 1-5hr
Onset: .5 hr - 1hr
Intermediate
Peak:6-14 hr
Onset: 1-2 hr
Long-acting
Peak: none
Onset: 70 min
Class: Biguanides
Name: Metformin
Nursing/ Medical Interventions
Can not be given with IV contrats dye, can not have metformin 24 hours after dye
Given for prevention T2DM, Gestational diabetes, PCOS,
Does not have to be taken with food
Class: Biguanides
Name: Metformin
Adverse effects
GI upset, wt loss, lactic acidosis
Interacts with : EtOH, Iv contrast dye, cimetidine
What is the most common medication that causes hypoglycemia?
Sulfonylureas
(Glipizide, glyburide, glimepiride)
Class: Sulfonylureas
Name: Glipizide, glyburide, glimepiride
Nursing/ Medical Interventions
Must be taken with food
Class: Sulfonylureas
Name: Glipizide, glyburide, glimepiride
Adverse effects
Hypoglycemia
Weight gain
Interacts with: EtOH, NSAIDS, Beta-blockers, sulfonamide antibiotics, cimetidine
Class: Thiazolidinediones
Name: Pioglitazone
Nursing/ Medical Interventions
Add on to metformin used for T2DM
Class: Thiazolidinediones
Name: Pioglitazone
Adverse effects
Black box warning for heart failure
Class: SGLT-2
Name: Jardiance, Farxiga
Nursing/Medical Interventions
It can be used for chronic kidney disease, heart failure, and diabetes
taken once daily B4 breakfast
low profile risk’
If the glomerular filtration rate is less than 30 (stages 4-5) do not administer
Class: SGLT-2
Name: Jardiance, Farxiga
Adverse effects
caution in renal disease. because you’re peeing everything out sugar etc.
Class: GLP1
Name: Ozempic, Victoza
Nursing/ Medical Interventions
They all end in tide
Class: GLP1
Name: Ozempic, Victoza
Adverse Effects
Delays gastric emptying( gastroparesis )
pancreas releases more insulin (pancreatitis)
Weight loss
You have a patient that comes in for heart failure they’re discharging on diabetic medication. Which of the following medications would be contraindicated to give them?
Pioglitazone (Thiazolidinedione)
(Because it causes heart failure)
What causes weight gain?
insulin and sulfonylureas