Exam 3 Drugs

Question 1

Phentermine, Diethylpropion

Answer 1

Reducing food intake: sympathomimetic amine

3-3.6kg at 6 months

HA, insomnia, irritability, palpatations, nervousness

Question 2

Orlistat

Answer 2

Affecting fat absorption: lipase inhibitor

2.59kg at 6 months, 2.89kg at 1 year

Diarrhea, flatulence, bloating, abdominal pain, dyspepsia

Question 3

Locaserin

Answer 3

Selective serotonin 2C receptor agonist

5.6kg at 1 year

HA, dizziness, nausea

Question 4

Phetermine/topiramate CR

Answer 4

Reduce food intake, promote satiety, possible increased metabolic rate

8-10kg at 1 year

Dry mouth, paresthesia, constipation

Question 5

Naltrexone CR/ wellbutrin CR

Answer 5

Synergism via POMC activation; appetite suppression and reward center effects

6.5kg at 1 year

N/V, insomnia, dizziness, increased HR/BP

Question 6

Liraglutide

Answer 6

GLP-1 central appetite suppression, decreased gastric motility

5.9kg at 1 year

N/V/D, constipation, flatulence

Question 7

Timolol

Answer 7

Decreases aqueous humor production

BB

Question 8

Betaxolol

Answer 8

Decreases aqueous humor production

BB

Question 9

Latanoprost

Answer 9

Increases uveoscleral outflow

PG analog

Question 10

Bimatoprost

Answer 10

Increases uveoscleral outflow and increases travecular outflow

PG analog

Question 11

Tafluprost

Answer 11

Increases uveoscleral outflow

PG analog

Question 12

Trusopt/Azopt

dorzolamide, brinxolamide

Answer 12

Decreases aqueous humor production

CAI

Question 13

Brimonidine

Answer 13

Decreases aqueous humor production and increases uveoscleral outflow

A2AA