Exam 3 Cram

Question 1

What is important about Cis loop receptors

Answer 1

have 5 subunits

Question 2

NMDA Coincidence Detector

Answer 2

Mg block needs depolarization and AMPA, require depolarization and glutamate

Question 3

What is NMDA important for

Answer 3

long term potentiation

Question 4

Ionotropic

Answer 4

GABA - A and GABA-C, leads to hyper polarization

Question 5

what are the Two principal signal transduction pathways of G protein-coupled receptors:

Answer 5

the adenylyl cyclase – cAMP signal pathway, and the Phospholipase C

Question 6

GQ- has two of what?

Answer 6

split pathways and you get DAG and IP3

Question 7

Phosphorylation

Answer 7

adding phosphate group

Question 8

What plays a primary role in ERK2

Answer 8

Serine and threonine

Question 9

What are two transcription factors

Answer 9

Mapk and Creb

Question 10

why do people administer L dopa in parkinsons

Answer 10

because it can cross blood brain barrier because dopamine cants

Question 11

What is the role of NE arousal and stress

Answer 11

important in ADHD

Question 12

Where does serotonin come from

Answer 12

tryptophan

Question 13

Where are CB1 receptors expressed, and where are they found

Answer 13

Expressed In the brain, Found in adipose tissue, liver, muscle, intestines, pancreas

Question 14

Where are CB2 receptors expressed

Answer 14

Expressed in immune cells

Question 15

TRP channel function

Answer 15

Specialized Sensory Transducers, critical for pain sensing

Question 16

TRPV1 is an

Answer 16

inflammation sensor

Question 17

TRPM8 is activated by

Answer 17

menthol

Question 18

TRPA1 is activated by

Answer 18

horseradish

Question 19

what do antidepressants do

Answer 19

Block serotonin transporter

Question 20

What are the nine catecholamines

Answer 20

Dopamin, norepinephrine, epinephrine, TH, AADC, DBH, PNMT, L-dopa, L-tyrosine

Question 21

Where in the brain is dopamine found

Answer 21

Substantia Nigra, and VTA

Question 22

Where in the brain is Norepinephrine found

Answer 22

Locus Coeruleus

Question 23

Where in the brain is Epinephrine found

Answer 23

Medullary epinephrine neurons

Question 24

Where in the brain is Serotonin found

Answer 24

raphe nuclei