Exam 3

Question 1

What is the prototype from proton pump inhibitors and what do they end in?

Answer 1

Omeprazole, -prazole

Question 2

What is the MOA of omeprazole?

Answer 2

They block 95% of acid production

Question 3

Which medication is the most effective for GI issues and what line of drug is it/why?

Answer 3

Omeprazole, 2nd line drug due to adverse effects

Question 4

Is omeprazole short or long term use? what is the drug class?

Answer 4

Short, Proton Pump Inhibitor

Question 5

What are adverse effects of omeprazole?

Answer 5

gastric cancer (d/t pH change), osteoporosis with long term use, c diff with delayed release forms in hospitalized patients

Question 6

What are contraindications of omeprazole?

Answer 6

Hypersensitivity, children under 18 years with an OTC formula

Question 7

How should omeprazole be based on children under 18?

Answer 7

By weight

Question 8

What are interactions of omeprazole?

Answer 8

Mineral deficiencies with long term use, food decreases absorption

Question 9

What are nursing interventions for omeprazole?

Answer 9

limit drug therapy to the lowest dose and shortest duration possible

Question 10

What is patient education for omeprazole?

Answer 10

It needs to be taken 20-30 minutes before eating; do not crush, chew or break; it can be mixed with applesauce or water

Question 11

What is the pharmacologic class for omeprazole?

Answer 11

Proton Pump Inhibitor (PPI)

Question 12

What is the pharmacologic class for famotidine?

Answer 12

Histamine 2 Antagonist

Question 13

What is the drug for Histamine 2 Antagonist?

Answer 13

Famotidine

Question 14

What is important about cimetidine?

Answer 14

Males and females may leak milky substance from breasts and has a higher risk of adverse effects, higher risk of impotence, reduced libido, gynecomastia, galactorrhea and CNS effects

Question 15

What is the MOA of famotidine?

Answer 15

It neutralizes stomach acid and prevents 70% of acid secretion

Question 16

What are adverse effects of famotidine?

Answer 16

Gynecomastia (enlarged breast tissue), reduced libido, impotence (ability to achieve erection) and bradycardia if given too fast by IV

Question 17

What are contraindications of famotidine?

Answer 17

Do not give antacids w/in 1 hr of H2 receptor antagonist, smoking decreases effectiveness, children under 12 should not take the OTC form

Question 18

T/F Children can have rx form of famotidine as long as it is weight based and separate from antacids.

Answer 18

True