Exam 3 Flashcards

1
Q

What are the three main functions of mucous membranes?

A
  1. Absorption
  2. Excretion
  3. Protection
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2
Q

What are the masticatory (keratinized) mucosa?

A
  • gingiva

- hard palate

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3
Q

What are the lining (non-keratinized) mucosa?

Alcohol By Volume? F*****g Sick

A
  • alveolar
  • buccal
  • ventral surface of tongue
  • floor of mouth
  • soft palate
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4
Q

Specialized mucosa

A

-dorsal surface of tongue (taste buds)

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5
Q

What are the 4 layers of the mucous membranes?

A
  • Epithelium
  • Lamina propria
  • Submucosa
  • Periosteum
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6
Q

What is the mucous membrane called that is missing the submucosal layer?

A

-mucoperiosteum

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7
Q

Which tongue papilla has lymphoid tissue?

A

-foliate

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8
Q

What lesion has foamy histiocytes and typically is caused by trauma?

A

Mucoceole

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9
Q

What are von ebner glands?

A

-salivary glands associated with the circumvalate papilllae that secrete pure serous secretions to clear out taste buds to continue tasting.

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10
Q

Why might a tooth become ankylosed?

A

-trauma that destroys the PDL so only osteoblasts are available to head the damaged site.

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11
Q

What part of the palate is the “glandular zone”?

A

-posterior 1/2

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12
Q

What structure helps hold the epithelial layer to the connective tissue layer in mucous membranes?

A

Epithelial Rete Pegs

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13
Q

What is parakeratosis?

A

retention of pyknotic nuclei in the stratum corneum

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14
Q

What is hyperkeratosis?

A

abnormal thickening of the stratum corneum

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15
Q

What is dyskeratosis?

A

abnormal keratinization below the level of the stratum corneum. (within granulosum or spinosum)

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16
Q

Acanthosis

A

hyperplasia (more cells) of epithelial layer

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17
Q

acantholysis

A

loss of intercellular attachments between epithelial cells

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18
Q

Metaplasia

A

reversible switch from one adult cell type to another (like columnar to squamous in respiratory tract in smokers)

19
Q

Dysplasia

A

disorderly growth by non-neoplastic growth of tissue (characterized by pleomorphism, hyperchromatism, loss of normal spatial org)

20
Q

What cell has dendritic morphology and is located in the stratum spinosum (not basale?

A

Langerhans cells (is an antigen trap)

21
Q

What cell has a rounded morph and is located in the stratum basale?

A

Merkel’s Cells

22
Q

What cells has rounded morph and is located in the basale AND and spinosum?

A

Lymphocytes

23
Q

The basement membrane is made up of what?

A

Basal Lamina (lamina lucida and lamina densa) + lamina reticularis

24
Q

What are the two key components of the lamina lucida in the basal lamina>

A
  • bullous pemphigoid antigen

- Type VII collagen

25
Q

What are the two key components of the lamina densa in the basal lamina?

A
  • Type IV collagen

- Type VII collagen

26
Q

What is the resident cell pop of the lamina propria?

A
  • fibroblast
  • monocyte
  • basophil
  • plasma cell
  • endothelial cell
27
Q

What do Mast Cells do?

A

secrete inflammatory mediators like histamine and heparin

28
Q

What do plasma cells do?

A

synthesis of immunoglobulins

29
Q

What do neutrophils do?

A

phagocytic cell that neutralizes antigens

30
Q

Taste Sensation for the Anterior 2/3 of tongue supplied by the…

A

Facial Nerve CN VII

31
Q

Taste sensation for the posterior 1/3 of the tongue supplied by the…

A

Glossopharyngeal Nerve CN IX

32
Q

Innervation for the soft palate is supplied by the….

A

facial nerve

33
Q

Innervation for the walls of the pharynx and epiglottis is supplied by the…

A

vagus nerve CN X

34
Q

What characteristic does lichen planus have?

A

T-lymphocyte and langerhans cell hyperplasia infiltration

35
Q

What is benign inflammation and desquamation of the epithelial layer?

A

geographic tongue

36
Q

Can leukoplakia be scraped off?

A

No

37
Q

What is notable about leukoplakia?

A

It is considered precancerous

38
Q

Most common site for oral squamous cell carcinoma?

A

posterior and lateral portion of tongue Male gender bias (3:1)

39
Q

keratin pearls and invasive islands of malignant squamous epithelial cells are signs of…

A

squamous cell carcinoma

40
Q

What is mucosal pemphigoid?

A

Accumulation of IgG and C3 along the basement membrane that causes separation of basement membrane layers since pemphigoid adhesion antigen is found in the lamina lucida. Female biased (2:1)

41
Q

What is the Nikolsky sign?

A

Sign for pemphogoid where mucous membrane separates with light force

42
Q

Condition where structures of ectodermal origin do not develop. What are these structures?

A

Ectodermal dysplasia: hair, eyebrows, eye lashes, teeth, sweat glands

43
Q

What is a peripheral ossifying fibroma? Cancerous? What does it look like histologically/

A

-maturation of pyogenic granuloma. Thought to be reactive not neoplastic so not cancerous. gingival mass with islands of calcified material (from periosteum)