Exam 3 Flashcards
How does multicellular organisms begin life?
Multicellular organisms begin life as a single cell life
Asexual reproduction
Doesn’t require sperm and egg
Require in sexual reproduction
Why is cellular reproduction necessary?
production of both new cells and new organisms
Cell division
parent cell contents divides into two daughter cells
Cell Growth
cell duplicates its contents (including DNA and organelles)
Chromation
DNA and associated proteins have the appearance of thin threads
DNA
periodically wound around histones to form nucleosomes
How many chromosomes does humans have
46 Chromosomes
What is sister Chromatids
Duplicated chromosomes are composed of sister chromatids joined at the centromere
What does each sister chromatid have
Identical DNA
Prophase
chromosomes are visible under microscope in condensed pairs
Metaphase
chromosomes line up along equatorial plate
Anaphase
chromosomes are pulled to opposite poles of cells
Telophase and Cytokinesis
two distinct cells are visible under the microscope
what happens mitosis begins?
DNA is replicated
what does each chromosomes consists of?
two sister chromatids attached at a centromere
Mitosis differs in plants and animals
Plant- have centrosomes but lacks centrioles
Animals- each centromoses has two centrioles and an sister (array of microtubules)
Cell plate
newly formed plasma membrane
G1 check point
cell committed to divide after this point
can enter G0 if checkpoint not passed
G2 checkpoint
Verifies that DNA replicated
DNA damage repaired
Mitotic stage checkpoint
Between metaphase and anaphase
all chromosomes must be attached to spindle to pass
Signal
a molecule that stimulates or inhibits an events
External signals
comes from outside the cell
internal signals
come from inside the cell
Kinases
removes a phosphate from ATP and add it to other molecules
Cyclins
internal signals present only during certain stages of the cell cycle
Epidermal growth factor
(EGF) stimulates skin near an injury to finish cell cycle and repair injury
Hormone estrogen
stimulates lining of the uterus to divide and prepare for egg implantation
Contact inhibition
cells stop dividing when they touch
Proto-oncogenes
code for proteins that promote the cell cycle and inhibits apoptosis. They are often likened to the gas pedal of a car because they accelerate the cell cycle
Tumor suppressor genes
code for proteins that inhibits the cell and promote apoptosis
Carcinogenesis
development of cancer