Exam 3 Flashcards
Breast cancer is the most common new cancer case in the U.S., at ___% of new cases.
29
What is the probability of developing breast cancer for females?
1 in 8
What is the highest cause of death by cancer for women in the U.S.?
Lung cancer (26%) - breast is second at 14%
Describe the probability of developing breast cancer with age.
Increases as age increases (from 1 in 1,681 at age 20 to 1 in 27 at age 70)
What are risk factors for breast cancer?
- Being a woman
- Increasing age
- Race/ethnicity
- Personal or family history of breast cancer
- Menstrual/pregnancy ihistory
- Prior abnormal biopsies
- Prior ionizing radiation
- Dense breast tissue
Discuss the incidence of breast cancer with age.
Increases with age until age 80, then it drops off or levels out
Breast cancer is most common in which ethnicities?
Most common in white and African American populations; mortality rate is highest in African American population
What is the greatest risk factor for breast cancer?
Previous history of breast cancer; 10 year risk of breast cancer in the contralateral breast is 1% per year pre-menopause and 0.5% per year post-menopause
The vast majority of breast cancer is ___ (familial, hereditary, sporadic).
Sporadic (70-80%)
What increases risk for breast cancer 2-3 fold with respect to menstrual cycle and pregnancy history?
- Early menarche (<12)
- Delayed menopause (>55)
- First live birth after age 30
- No children
Where is the majority of breast tissue found?
Upper outer quadrant
What is the age range for mammograms suggested by USPSTF?
50-74, ever 2 years
True or false - negative imaging rules out cancer.
False
What are the exceptions to the rule that a biopsy is required for all lumps?
- Simple cyst on ultrasound
- Young woman with known fibroadenoma
- Breast mass is clinically stable for >2 years
What are retraction signs?
Dimpling, changes in contour, and retraction or deviation of the nipple (caused by shortening of fibrotic tissue seen in breast cancer)