Exam 3 Flashcards
Delaney Clause
Carcinogens
ADI
Level considered to be safe over a lifetime
Teratogen
Caused birth defects
Carcinogen
Causes cancer
LD50
Acute-kills 50% of animals. Large single toxic dose. Screening
Short-term toxicity
Helps determine dose for long term studies. Control +levels. What does it do at hi levels
Ames test
Mutengenic potential
The NOEL is the level at which no adverse effect occurs in animals determined from sub chronic feeding studies .
True:
= the highest dose that results in no detectable damage to the animal.
The ADI is:
Estimated by dividing the no-observed-effect level (NOEL) of a test substance by the safety factor (100)
May take well over 10 years to gain approval
We can use additives to replace GMPs? (T/F)
False
Food additives require pre-market approval? (T/F)
True
What does GRAS mean?
Generally recognized as safe: List of affirmed safe ingredients because of 1958 law. Egs. Salt, sugar, vinegar
Preservatives
Antioxidants, antimicrobials, parentheses
Emulsifiers
Lecithin, egg yolk
Thickeners
Gums, starch, bacterial
Types of antioxidants
Vitamin C, sulfur, BHT
Colors
Controversial
“Natural” means it is safe (T/F)
False
Describe what organic food means.
Specific standards. A list of approved chemicals. Manure…ect. Expensive
Does an organic food mean it’s not a processed food?
What are some implications of using biotech for treating genetic diseases?
Insurance? Ability to reproduce? Employers?
What 4 characteristics must bioengineered foods have if they are not labeled?
- Change must be well characterized
- Genetic change must be stable
- Toxicants and anti-nutritional factors must be at or below current cultivar. Don’t introduce an unknown allergen.
- Nutritional profile the same or better
RFLP
Looks for patterns in DNA
PCR
Amplifies DNA
Restriction enzyme
Cuts DNA into pieces at specific sequences
Antisense RNA
Backward strand to turn gene off
Biotechnology
Transfer of DNA