Exam 3 Flashcards

1
Q

Versed

A

Midazolam
Benzodiazepine (GABA agonist)
rapid onset of action (Use for acute agitation)
T1/2 = 1-3 hrs
active metabolite
Prolonged sedation may occur (obese, CKD, low albumin)

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2
Q

Versed

A

Midazolam
Benzodiazepine (GABA agonist)
rapid onset of action (Use for acute agitation)
T1/2 = 1-3 hrs
active metabolite
Prolonged sedation may occur (obese, CKD, low albumin)

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3
Q

Valium

A
Diazepam
Benzodiazepine (GABA agonist)
rapid onset
T1/2 = 20-80 hrs (NO CI)
active metabolite
Use for short term sedation or status epilepticus
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4
Q

Diprivan

A

Propofol
Anesthetic with sedative and amnesic properties
GABA agonist/NMDA antagonist
Ideal for short term sedation (extubation, monitoring neuro function )

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5
Q

Diprivan

A

Propofol
Anesthetic with sedative and amnesic properties
GABA agonist/NMDA antagonist
Ideal for short term sedation (extubation, monitoring neuro function )

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6
Q

Valium

A
Diazepam
Benzodiazepine (GABA agonist)
rapid onset
T1/2 = 20-80 hrs (NO CI)
active metabolite
Use for short term sedation or status epilepticus
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7
Q

Ativan

A

Lorazepam
Benzodiazepine (GABA agonist)
T1/2 = 10-20 hrs
NO active metabolite (faster recovery from sedation)
IV formula contains propylene glycol –> acute renal failure
Less lipophilic (Slower onset, longer DOA)

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8
Q

Diprivan

A

Propofol
Anesthetic with sedative and amnesic properties
GABA agonist/NMDA antagonist
Ideal for short term sedation (extubation, monitoring neuro function )

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9
Q

Precedex

A

Dexmedetomidine
sedative with analgesic effects
No respiratory depression
Selective alpha-2 agonist (inhibits release of NE, decreases BP and HR)
Be prepared to administer analgesics when weaning pt
Do NOT use in pts with low MAP

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10
Q

Romazicon

A

Flumazemil
BZD reversal agent
GABA antagonist

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11
Q

Amidate

A
Etodimate 
GABA agonist 
Rapid, short term sedation 
Minimal respiratory and CV depression 
Uses: cardio version, airway procedures, minor invasive procedures 
ADE: N/V, myoclonus and convulsions
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12
Q

Ketalar

A

Ketamine
NMDA antagonist
Sedation, analgesia, and amnesia simultaneously
Uses: painful procedure of short duration (Burns, bone re-setting)
ADE: hallucinations, sialorrhea, Inc ICP, tonic-clonic seizures

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13
Q

Pentothal

A

Thiopental

barbiturate

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14
Q

Nembutal

A

Pentobarbital

barbiturate

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15
Q

Anectin

A

Succinylcholine - depolarizing neuromuscular blockade
Uses: intubation
Can’t use long term due to inc K levels, histamine release, malignant hyperthermia

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16
Q

Barbiturates

A

MOA: works on GABA receptors, produces dose dependent sedation or anesthesia
Uses: Induction of barbiturate coma - refractory intracranial HTN and epileptic seizures
ADE: respiratory and cardiovascular depression

17
Q

Morphine

A

oldest opiate in use
most hydrophilic
hepatic metabolism –> Morphine 3-glucuronide, Morphine 6-glucuronide - both eliminated renally and accumulate w/ renal and hepatic dysfunction
can induce histamine release

18
Q

Sublimaze

A

Fentanyl - opioid analgesic
preferred in pts with renal failure
fat soluble - inc Vd, inc risk of accumulation/delayed recovery
No histamine release

19
Q

Anectin

A

Succinylcholine - depolarizing neuromuscular blockade
Uses: intubation
Can’t use long term due to inc K levels, histamine release, malignant hyperthermia

20
Q

Tracrium

A

Atracurium - non depolarizing neuromuscular blockade

benzylisoquinolone

21
Q

Nimbex

A

Cistracurium - non depolarizing neuromuscular blockade

benzylisoquinolone

22
Q

Pavulon

A

Pancuronium - non depolarizing neuromuscular blockade

aminosteroid

23
Q

Zemuron

A

Rocuronium - non depolarizing neuromuscular blockade

aminosteroid

24
Q

Norcuron

A

Vercuronium - non depolarizing neuromuscular blockade

aminosteroid

25
Q

Quinidex

A

Quinidine - Class 1A
anti-arrhythmic
Sodium and Potassium channel blockers

26
Q

Pronestyl

A

Procainamide - Class 1A
anti-arrhythmic
Sodium and Potassium channel blockers

27
Q

Norpace

A

Disopyramide - Class 1A
anti-arrhythmic
Sodium and Potassium channel blockers

28
Q

Xylocaine

A

Lidocaine - Class 1B
anti-arrhythmic
Sodium channel blocker

29
Q

Mexitil

A

Mexiletine - Class 1B
anti-arrhythmic
Sodium channel blocker

30
Q

Tambocor

A

Flecainide Class 1C
anti-arrhythmic
Calcium and potassium channel blocker

31
Q

Rythmol

A

Propafenone Class 1C

anti-arrhythmic

32
Q

Tikosyn

A

Dofetilide Class III

anti-arrhythmic

33
Q

Cordarone

A

Amiodarone Class III

anti-arrhythmic

34
Q

Multaq

A

Dronedarone Class III

anti-arrhythmic

35
Q

Betapace

A

Sotalol Class III

anti-arrhythmic

36
Q

Corvert

A

Ibutilide Class III

anti-arrhythmic

37
Q

Calan

A

Verapamil Class IV
anti-arrhythmic
Calcium channel blocker

38
Q

Cardizem

A

Diltiazem Class IV
anti-arrhythmic
Calcium channel blocker