Exam 3 Flashcards
3 christs of Ypsilanti
Milton Rockeach
* worked at a psych hospital where in 3 different units at the same time 3 men had the same delusion that they were jesus christ
* the 3 got into conflicts all the time
* Clyde resolved that the other 2 christs were dead (corpses with machines inside them that did the talking)
* joseph concluded that the other 2 christs were crazy and that research assistants were his allies
* leon thought other men were faking, crazy, wanted recognition, or were lesser gods
- all 100% believed their delusions
positive symptoms of schizophrenia
delusions
hallucinations
command auditory hallucinations
delusions
false, fixed beliefs
disturbance in thought content
over 90% people with schizophrenia have delusions
common types of delusions
granduer
persecution
thought broadcasting
insertion/withdrawl
reference
control
somatic
delusions of grandeur
great power, knowledge, talent
*all 3 christs would have this
- less common
delusions of persecution
paranoid
* police are in on it
* more common
thought broadcasting
ones private thoughts are being broadcasted to others against your will
thought insertion/withdrawl
thoughts are being taken out of your brain without knowledge
thought that your roommate is stealing information from your brain while you’re sleeping so you stay up all night
delusions of reference
things in environment have a special meaning only intended for you
delusions of control
thoughts being controlled by external agents such as robots
somatic delusions
part of your body is diseased or altered or believing your intestines have been replaced by snakes
symptoms of schizophrenia exist in
three dimensions:
positive
negative
disorganized
positive symptoms aka
pathological excesses
hallucinations
positive symptom of schizo
false sensory experiences
experienced as real
most common hallucination
auditory
types of hallucinations
visual
gustatory (taste)
olfactory (smell)
tactile (touch) ** red flag
why is tactile (touch) symptom of hallucination a red flag for therapists
not very common and may be a red flag for malingering
do hallucinatory symptoms occur one by one or together
can all occur together
auditory hallucinations
often voices are known or of God/Devil
most people report hearing more than on voice
most of the time they utter rude, vulgar, critical comments
command auditory hallucinations
command or not command
- command- voices tell person to do something - difficult to ignore and often telling the person to do something really bad to themselves or others
negative symptoms of schizophrenia aka
pathological deficits
negative symptoms of schizophrenia
alogia
avolition
restricted affect
anhedonia
social withdrawl
what is a poor prognostic sign of schizophrenia
preponderance - excess superiority
alogia
poverty of speech
* speak less often, use fewer words
(-) schizo
avolition
apathy, inability to initiate or persist in goal directed activities
- appears as lazy when really they truly do have significant challenges doing a particular task
*inability to start or complete paying bills even when urgent
(-) schizo
social withdrawl
when more psychotic, drawn deeper into social withdrawal which worsens dissociation from reality and makes delusions and hallucinations worse
(-) schizo
restricted affect
low emotional expression
(-) schizo
anhedonia
inability to feel pleasure
(-) schizo
disorganized symptoms of schizo
disorganized speech or behavior
thought disorder
catatonia
posturing
stereotyped movements
inappropriate affect
disorganized speech
disorganized symptom of schizo
does not make sense
* could reflect an underlying thought disorder
loose associations (lack of connection between ideas)
clanging (words that sound the same but dont make sense together)
perseveration (stuck on idea)
neologisms (new word)
malapropisms (mistaken use of word in place of similar sounding one)
disorganized behavior
disorganized symptom of schizo
poor/unusual hygiene, dress
catatonic stupor (can’t move or respond- stare into space)
posturing (hold specific position)
stereotyped movements (repetitive movements)
inappropriate affect (hysterically laughing in serious situation)
DSM Schizophrenia
two or more for one month:
- delusions
- hallucinations
-disorganized speech
-disorganized/catatonic behavior
- negative symptoms
continuous signs for 6 months to a degree that impairs social/occupational functioning
what % of population does schizophrenia affect
1%
are there differences in # of men vs women cases in schizophrenia
no
when is schizophrenia typically diagnosed
late adolescence or early adulthood
is schizophrenia progressive
no only debilitating
if a person has anosognosia, what is their diagnosis
anosognosia = lack of insight
- important for understanding schizophrenia
- a person with schizophrenia lacks insight into their mental health condition
- not knowing you have schizophrenia and lacking insight into fact you may be hallucinating
is genetics a factor in developing schizo
yes significant genetic component
as the degree of genetic similarity increases in people so does the risk of schizophrenia
60-80% heritability
* identical twins have a greater genetic similarity so they have a higher chance of developing schizo if other has it
environmental factors: schizo
really early - prenatal and perinatal
viral infection
maternal stress
birth complications
infants born to mothers who had the fly in their third trimester have significantly elevated risks of
schizophrenia
- this is because mothers antibodies for flu cross the placenta which may disrupt the development of the fetal brain
if a mother is stressed and has high cortisol, what is fetus at risk for developing
schizo because cortisol crosses placenta and has negative effects on devloping brain
if a baby is born in breach position or after prolonged labor or with umbilical cord wrapped around their neck what are they more at risk for developing
schizo due to lack of O2 to brain
neurodevelopmental perspective
the brain of someone with schizophrenia may be impacted early on in life
- maybe genetics or environmental factors
** but the symptoms do not reveal themselves until adolescence or early adulthood which coincides with a significant period of brain maturation in prefrontal cortex
dopamine hypothesis
schizophrenia results from excessive levels of dopamine activity
increased dopamine levels may be result of increase dopamine receptors on post-synaptic cell
how did the dopamine hypothesis come about
based on the action of thorazine which is a first generation antipscyhotic, which blocks dopamine receptors (D2 receptors)
blocking dopamine receptors = reduced hallucinations and delusions
first generation psychotics
thorazine
blocks dopamine receptor (D2 receptors) and reduces hallucinations and delusions (70%)
second generation antipsychotics
clorazil and risperdal
block D2 and other dopamine receptors and impact other NTs (Glutamate, GABA, serotonin)
70% much improved- mostly positive symptoms
what is the front line txt for schizo
second generation antipsychotics
side effects of second generation antipsychotics (clozaril and risperdal)
fewer extrapyramidal symptoms (EPS)
less tardive dyskinesia
weight gain and increased risk of diabetes, hypertension, and CHD
fewer extrapyramidal symptoms (EPS)
neurological disturbance: muscular rigidity, tremors, restless agitation, involuntary postures, Parkinsonism
Parkinsonism
difficult initiating motor movements, tremors (antipsychotic medications mimic antipsychotics)
less tardive dyskinesia (TD)
involuntary movements of :
the mouth (lip smaking, tongue thrusting)
eyes (rapid blinking)
fingers or limbs
what causes TD more: 1st or 2nd gen antipsychotics
1st generation
can TD be fixed
sometimes if caught early enough
when can a schizo stop taking meds
never