exam 3

Question 1

cocaine

Answer 1

inhibits dopamine reuptake, stimulant

Question 2

amphetamine and methamphetamine

Answer 2

increase monoamine release, stimulant

Question 3

amphetamine

Answer 3

stimulant

Question 4

methamphetamine

Answer 4

stimulant

Question 5

phenmetrazine

Answer 5

stimulant

Question 6

diethylpropion

Answer 6

stimulant

Question 7

methylphenidate

Answer 7

stimulant

Question 8

reserpine

Answer 8

inhibits vesicular monoamine transporter, so vesicles don’t fill with DA

Question 9

MPPP

Answer 9

synthetic opioid

Question 10

meperidine

Answer 10

synthetic opioid

Question 11

selegiline

Answer 11

inhibits monoamine oxidase B, treating parkinsons by decreasing DA degradation

Question 12

entacapone and tolcapone

Answer 12

COMT inhibitors, prevent DA breakdown

Question 13

pramipexole (miraprex)

Answer 13

D2 type DA-R agonist

Question 14

bromocriptine

Answer 14

dopamine receptor agonist

Question 15

phenothiazine

Answer 15

precursor to antipsychotics, acts as an antimalarial along with methylene blue and promethiazine

Question 16

clozapine

Answer 16

partial serotonin receptor agonist, second generation/atypical antipsychotic that may also increase NMDAR activity, mood stabilizing

Question 17

risperidone

Answer 17

anti cholinergic, serotinergic, adrenergic, histaminergic

Question 18

d-cycloserine

Answer 18

increase NMDAR activity via NMDAR agonists, glutamate can affect DA

Question 19

bioterpine and n-methylglycine sarcosine

Answer 19

glycine transporter antagonists, increase NMDAR activity

Question 20

phenylephrine

Answer 20

alpha-adrenergic receptor agonist, decongestant, used instead of pseudoephedrine

Question 21

clonidine

Answer 21

adhd, reduce panic/anxiety and help with withdrawal, alpha-adrenergic agonist, reduces BP

Question 22

yohimbine

Answer 22

alpha-adrenergic antagonist w/ high affinity for a2 receptors, stimulant and aphrodisiac

Question 23

prazosin

Answer 23

antihypertensive anxiolytic inverse agonist at a1 type receptors

Question 24

albuterol

Answer 24

opens up air passeges, beta-adrenergic agonist that may cause anxiety

Question 25

propranolol

Answer 25

beta-adrenergic receptor antagonist, reduces BP and manages anxiety, arrythmias

Question 26

PCPA

Answer 26

depletes serotonin by preventing tryptophan hydroxylase and preventing production

Question 27

amitriptyline,desipramine, imipramine, nortiptyline, protriptyline, trimipramine

Answer 27

triciclyc antidepressants

Question 28

venlafaxine/effexor

Answer 28

second generation SNRI

Question 29

duloxetinr

Answer 29

SNRI second gen

Question 30

prozac, paxil, celexa, luvox, zoloft

Answer 30

SSRIs

Question 31

tyramine

Answer 31

found in many foods, metabolized by MAO-A and stimulates 5-HT and NE signalling

Question 32

tranylcycpromine

Answer 32

MAOI for depressionp

Question 33

phenelzine

Answer 33

MAOI for depression

Question 34

LSD, DMT, DMT, psilocin and psilocybin

Answer 34

hallucinogens acting on 5-ht receptors (indolamines)

Question 35

phenethylamines (NE, mescaline, amphetamine, dom, tma)

Answer 35

act on 5-ht receptors

Question 36

NBOMe

Answer 36

full agonist of 5-HT2a receptors, hallucinatory experiences and hypertensive/vasoconstrictive effects

Question 37

somatripan

Answer 37

5ht1d agonist for migraine

Question 38

almotriptan

Answer 38

5-ht1 agonist

Question 39

buspirone

Answer 39

5-ht1a agonist, anxiolytic

Question 40

aripiprazole

Answer 40

partial 5-ht1 and d2 agonist, 5ht2 antagonist, antipsychotic

Question 41

olanzapine

Answer 41

5-ht antagonist

Question 42

ondansetron, dolasetron, granisetron

Answer 42

5-ht3 antagonist