Exam 3 Flashcards
What is GINA for?
Protect against the use of genetic information to discriminate in health insurance and employment
Allostasis
The process by which the body responds to stressors in order to regain homeostasis // The body’s adaptation to predictable and unpredictable changes in the environment
Allostatic Load
The cumulative burden of chronic stress and life events // The cost of chronic exposure to elevated / fluctuating internal responses d/t chronic or repeated challenges that the person experiences as stress
Stress
Body’s response to changing factors within yourself / the environment
Epigenomics
Study of molecular signals that tell genomes how to behave and their relationships to health
Epigenetics
Non-genetic influences on gene expression
DNA methylation
Methyl molecule blocks transcription which results in lack of protein synthesis
Barker Hypothesis
Hypothesis that states adverse fetal life context leads to increased risk of adult disease
Genetics
The study of heredity and the transmission of characteristics from across genetics
Gentotype
Molecular structure of organism, expressed via production of protein
Phenotype
Observable characteristics of an organism
What is the complex disease phenotype pathway
Genetic susceptibility -> exposure -> epigenetic modification -> complex disease
What is the exposome
General external environment, specific external environment, internal environment
What are the objectives of epidemiology
Population, determinants of health, distribution, frequency, disease causation, application
What is the epidemiologic triangle
Relationship between agent, host, and environment related to communicable diseases
What is the web of causation
Map like model to investigate relationships r/t chronic diseases
What is the surveillance method of epidemiology
Ongoing, systematic collection, analysis, and interpretation of health related data essentials
What is the descriptive method of epidemiology
Describing who, what, when, and where
What is the analytic method of epidemiology
Examine relationships between who, what, when, where to determine the why
What is the formula for rate
number of occurrences in a time period / total population in a time period (all times K)
What is the formula for risk
number of people who experience an event / # of all people who are at risk for experiencing the event
What is the formula for odds
number of people who experience an event / # of all people who DO NOT experience the event