Exam 3

Question 1

Reduction of Ketone or Aldeyhyde to an Alcohol

Answer 1

Strong reducing agent such as 1)LiAlH4 2)H20

Question 2

Reduction of Acid chlorides, Esters, and Carboxylic acids results in…

Answer 2

an alcohol

Question 3

Reduction of Amides

Answer 3

Amines

Question 4

Aldehydes and Ketones nucleophilic addition

Answer 4

Organometallic bases, RLi and RMgX
Creates an alcohol

Question 5

Nucleophilic Addition to Acid Chlorides and Esters

Answer 5

Organometallic bases, RLi and RMgX
Adds 2 equivalent R groups

Question 6

Organometallics to Carboxylic acids

Answer 6

1)CO2, 2)H2O

Question 7

Nucleophillic addition of an acid chloride, but doesn’t react with an aldehyde or ketone

Answer 7

R2CuLi

Question 8

Epoxide to alcohol

Answer 8

Organometallic bases, 1)RLi and RMgX 2)H2O

Question 9

This reacts with the beta carbon in alpha, beta unsaturated ketones

Answer 9

R2CuLi

Question 10

Nucleophilic addition of -CN

Answer 10

NaCN, HCl, also reduces carbonyl

Question 11

Substitution of C=O for C=CR2

Answer 11

Wittig Reaction
Ph3P=CR2
(mechanism forms a four-membered ring)

Question 12

Aldehyde or Ketone to Imine

Answer 12

RNH2, acid catalyst
Imine has a R2C=NR

Question 13

Aldehyde or ketone to enamine

Answer 13

R2NH, acid catalyst
forms RC=CR-NR2

Question 14

Aldehyde or ketone to Acetal

Answer 14

2ROH, TsOH
R-2OR-H(R)

Question 15

Fisher esterfication

Answer 15

carboxylic acid + alcohol + sulfuric acid= ester+ H2O