Exam 2: Week 10, Diabetic/Neuropathic Ulcers Flashcards
Differentiate between type 1 and type 2 diabetes
Type 1: Developed at a young age
Type 2: Developed over time as a teen/adult (Much more common than type 1)
T or F? Individuals with type 2 diabetes are 2-4x more likely to have a heart attack or stroke, 5x more likely to get a foot ulcer/gangrene, and 17x more likely to have kidney disease, and is 8x more likely of going blind (most common cause of blindness)
True
Why are diabetic ulcers the hardest wounds to heal?
Because diabetes affects small arteries (capillaries) and the patient is sometimes unable to feel it
(Note: Arterial affects larger arteries, diabetic affects smaller arteries)
List some facts about diabetes
- 1/4 of people are unaware that they have the disease
- 4% higher mortality rate than those withiut diabetes
- 8% of patients with type II DM have PVD as well
- 50% will have contralateral ulcer within 18 months
- 50% will have second amputation within 3-5 years
- 70% of all amputations are due to DM
List the blood glucose guidelines for patients with diabetes
In General:
- 80-120 mg/dL before meals or when waking up
- 100-140 mg/dL at bedtime
(Note: people with DM may have >200 mg/dL after eating a meal)
List the hemoglobin (HgB) levels of a normal patient, a pre-diabetic patient, and a diabetic patient
Normal: <5.7%
Prediabetes: 5.7-6.4%
Diabetes: >6.5%
What affects does hyperglycemia have on the body?
- Changes RBCs, platelets, and capillaries
- Alters blood flows (micro-circulation)
- Increases microvascular pressure
Describe neuropathic ulcers
- Occurs as a result of nerve damage (neuropathy)
- Plantar aspect of the foot
- May occur under calluses
- May occur in places where pressure and friction are present when wearing inappropriate footwear
- Pain is usually absent/minimal
- Little to no drainage
T or F? Forefoot location accounts for the majority of all ulcers and heal faster than midfoot/heel ulcers, while charcot foot is most common near the midfoot
True
List the risk factor for vascular disease (PVD & accelerated atherosclerosis)
TcPO2/TCOM <30mmHg
List the risk factor for neuropathy
<5.07 monofilament
List the risk factor for abnormal foot function and inadequate footwear
Charcot, claw toes, hammer toes
List the risk factors for impaired healing and immune respone
Thickening of basement membrane (= less O2 delivery)
List some risk factors for neuropathic ulcers
- Inadequate care/education
- Poor vision
Which is more likely to cause a diabetic ulcer? Ischemia or neuropathy
Neuropathy
Describe neuropathy
- Most common complication of diabetes
- Affects 30-40% of type 2 and even more type 1
- May be caused by neural ischemia and segmental demyelination
- Symmetrical, distal
- Increases risk of plantar ulceration >3.5 times
- Affects sensory, motor, and autonomic systems
Why is it not uncommon to see an amputee develop an ulcer on the contralateral limb?
Because all the pressure is now on one limb rather than two
How can individuals with diabetes limit tissue damage?
Monitor/Regulate blood sugars
Where do venous, arterial, and neuropathic/diabetic ulcers form?
Venous: Lower limb
Arterial: Foot
Neuropathic/Diabetic: Foot
List the distribution of ulcers in the forefoot
Top of Big Toe: 8%
Top of Middle Toe: 8%
Bottom of Big Toe: 20%
Bottom of Mid Foot: 22%
Bottom of Middle Toe: 28%
Describe neuropathy
- Most common complication of diabetes
- Affects 30-40% of type 2 diabetics, and affects type 1 even more
- May be caused by neural ischemia (not enough blood to brain), or segmental demyelination
- Typically symmetrical and distal
- Increased risk of plantar ulceration (3.5x risk) because the patient is unable to feel sensation
T or F? Diabetic ulcers have “callused” edges whereas arterial ulcers have “punched out” edges
True
List the 3 types of neuropathy
Sensory Neuropathy:
- Gradual/painless
Motor Neuropathy:
- Leads to muscular atrophy (which increases plantar pressure)
- If patient controls his/her blood sugar, this patient should not get motor neuropathy
Autonomic Neuropathy:
- Sweat, callus, change in blood flow
Describe Sensory Neuropathy
- 50% of patients are unaware they have lost protective sensation
- Parasthesias (burning pain, tingling, aching)
- If patient is unable to feel a 5.07 monofilament test, patient is at risk for ulceration
Describe Motor Neuropathy
- Leads to paralysis/weakness of foot intrinsic muscles as a result of poor blood sugar control
- Decreased foot stability (especially during “stance phase”)
- Leads to deformities (hallux valgus, claw toe, high arch)
- Muscle atrophy increases pressure and shear forces to the foot
Describe Autonomic Neuropathy
- Dry, cracked skin due to increased ability to sweat
- Increased risk of callus formation
- Arteriovenous shunting leads to decreased perfusion (which decreases ability to heal/repair self)
- Uncontrolled vasodilation leads to osteopenia (can lead to charcot foot developing)
List the foot deformities
- PF contracture
- Varus/valgus
- Charcot foot
- Toe deformities
- Bunion
- Calluses