Exam 2 Topics Flashcards
paracrine cell communication
release of paracrine factor into tissue interstitial affects target cell in close proximity
endocrine cell communication
release hormones into blood which can effects target cells in multiple organs
neuroendocrine cell communication
triggered by action potentials that cause release of hormones into blood affecting target cells in multiple organs
communication by excitable cells connected by?
gap junctions
what constitutes a target cell?
expression of a receptor that can bind to a chemical messenger
receptors that bind neurotransmitters released by neurons
ligand-gated channels and G protein coupled receptors
Ligand-gated channels
inotropic receptors
G Protein coupled receptors (GPCR)
metabotropic receptors
Types of neurons
afferent, interneurons, efferent
Afferent neurons
propagate APs to brain and or spinal cord
Orientation of afferent neurons
dendrites, hillock, cell body = outside CNS
axon terminals = inside CNS
Classification of afferent neurons
location of dendrites and by stimulus modality detected
Interneurons
propagate APs within the CNS
Orientation of interneurons
all components found in brain and/or spinal cord
Classification of interneurons
where their cell body is found
Efferent neruons
propagate APs away from the CNS
orientation of efferent neurons
dendrites, cell body, hillock = inside the CNS
axon terminals = outside CNS
Classification of efferent neurons
location of the axon terminals; somatic or autonomic
Somatic efferents
motor neurons; axon terminals found ONLY in skeletal muscle
Autonomic efferents
axon terminals in internal organs and blood vessels
Afferents transduce different stimulus modalities into…
variable magnitude receptor potentials and variable frequency APs
What is responsible for specificity of an afferent detecting only one type of stimuli?
Specific type of ion channels found within the dendrites of the afferent