Exam 2 Tophat Questions Flashcards
T/F: There is a killed vaccine for FeLV. It would be important to know the vaccination history of a cat when testing for FeLV because vaccination could complicate the interpretation of the FeLV Antigen test.
False; we are looking for a virus, so Ab presence wouldn’t complicate the results of an Ag test
Yes/No: There is a vaccine for FIV. Would you expect it to complicate the interpretation of the
FIV antibody test?
Yes; Ab presence can be due to infected cat OR maternal Ab OR vaccine AB - the test doesn’t distinguish between them
What is the difference between a Th1, Th2, Th17, and Treg?
Mixture of cytokines they secrete
T/F: Th cells are a type of gamma/delta T cell.
False
T/F: αβ and γδ refers to the type of T cell receptor and these are two different T cell populations
True
The helper cell that is important in defense against intracellular pathogens (e.g. Salmonella) and the signature cytokine it secretes is interferon gamma is a _____ T cell.
Th1
The helper cell that is important in defense against helminth parasites and its signature cytokines result in B cells class switching to make IgE is a _____ T cell.
Th2
The helper cell that is important in defense against extracellular pathogens and fungi and its signature cytokines attract and activate neutrophils is a _____ T cell.
Th17
What T cells are important for controlling the immune response and preventing autoimmune disease (reaction to self-antigens)?
Treg cells
What do CTL and NK cells NOT do?
induce inflammation (they use apoptosis)
What cells produce type 1 interferon?
virally infected cells
Why is an animal susceptible to infection after a burn or severe injury with loss of skin?
The skin provides an important protective barrier
Where does secretory IgA provide protection?
on mucosal surfaces
Where does IgE provide protection?
Beneath mucosal surfaces
What 4 body systems/tracts are part of the common mucosal immune system?
- Respiratory tract
- GI tract
- Mammary glands
- Genitourinary tract
