exam 2 study guide #7 Flashcards
antigen
molecule capable of inducing an immune response
antibody
bivalent protein formed by B lymphocytes in response to foreign substance
packed cells
cells only, no plasma
Correspond antigens present
Type A
Type B
Type AB
Type O
-A antigens
-B antigens
-both A/B antigens
-none
Antibodies
Type A
Type B
Type AB
Type O
-b antibodies
-a antibodies
-neither a/b
-both a/b antiodies
Antibodies a and b are called naturally occurring antibodies because:
-result of natural exposure to substances in our environment during first few months of life
-form naturally in anyone who doesn’t have corresponding antigen
A serum
someone with type A blood
-b antibodies
An Rh negative man is tested and shown to have Rh antibodies. How do you explain this?
has received Rh positive blood transfusion at some time in his life
A Rh negative woman delivers a baby with Rh positive blood. This baby will suffer from erythroblastosis fetalis only if:
the mother previously delivered a baby with Rh positive blood and did not receive RhoGam
Which of the following individuals will have Rh antibodies?
-an Rh negative individual who has received a transfusion of Rh positive blood
-an Rh negative woman who has delivered an Rh positive child and not received a Rhogam injection
Explain the etiology of erythroblastosis fetalis by placing the events listed in the right column in the proper order.
1- Rh negative mom pregnant with Rh positive child
2- Rh positive fetal cells leak into mothers circulation during delivery
3- triggers immune response in mom who now produces Rh antibody
4- during 2nd pregnancy with another Rh positive baby, Rh antibody cross placenta into fetal circulation
5- maternal Rh antibody bid to fetal red blood cells
6- fetus suffers from destruction of red blood cells and is anemic and jaundiced at birth
Treatment of Rh positive mom with Rh negative baby using Rhogam:
-must be done within 72 hours of delivery
-injects the mother with Rh antibodies that destroy any fetal Rh positive cells before they can cause an immune response
-prevents production of Rh antibodies in the mother
-must be done following the delivery of all Rh positive babies
Genotype- blood type
Type A (homozygous)
IA IA
Genotype- blood type
Type A (heterozygous)
IA i
Genotype- blood type
Type B (homozygous)
IB IB