Exam 2: Preterm Labor Flashcards
What is considered preterm labor?
Occurrence of regular contractions accompanied by cervical change before the end of the 37th week
Leading cause of death within the first month of life
One of the biggest contributors to perinatal morbidity and mortality
Most common obstetric complication
Preterm births account for __% of neurological development disorders
75%
Risk factors for preterm labor
History of preterm delivery
African American
Multiple gestation
Low socioeconomic status
Smoking, ETOH, elicit drug use
Hypertension
Diabetes
Current infections
Maternal age
Poverty
BV
Nutrition
Short pregnancy intervals
Stress
Late/no prenatal care
Domestic violence
Periodontal disease
Reproductive technology
Bleeding
History of preterm delivery increases risk for preterm labor by how much?
Triples risk
African American race increases risk for preterm labor by how much?
Doubles risk
Bacterial vaginosis increases risk for preterm labor by how much?
50% increased risk
Signs and symptoms of preterm labor
Abdominal pain
Cramping
Contractions (more than 6/hour)
Low, dull backache
Pelvic pressure
PROM
Increased vaginal discharge
Dilation/effacement of cervix
N/V, diarrhea
Preterm premature rupture of membranes (PPROM)
30-40% of preterm labor
May occur spontaneously
Exact cause unknown (may be associated w/ injection, abnormal placental implantation, abruption)
Likely to occur in subsequent pregnancies
Preterm labor diagnosis
Presence of cervical change
Fetal fibrocetin (fFN) can get a lot of false positives, negative result is important because it indicates you won’t deliver in the next 7 days
What are the associated neonatal risks to preterm labor?
Respiratory distress syndrome
Infection
Congenital heart defects
Thermoregulation problems (acidosis, intraventricular hemorrhage)
What is the first line of evidence-based therapeutic management for preterm labor?
IV hydration with isotonic solution
What is given for fetal lung maturity?
Steroids, Betamethasone (IM)
Stimulates surfactant production
May elevate maternal glucose levels
Needs 24 hours to be effective
What is given for neuro-protection?
Magnesium sulfate
Magnesium sulfate
Relaxes uterine muscle to arrest contractions
Antidote: Calcium gluconate
Indomethacin
Suppresses preterm labor by blocking production of prostaglandins, which inhibits uterine contractions
Can cause premature closure of ductus arteriosus
Can cause oligohydramnios