Exam 2 Practice Quizzes Flashcards
Which of the following is NOT an adverse effect of androgen-like progestins?
a. weight gain
b. acne
c. venous thromboembolic disease
d. hirsutism
c. venous thromboembolic disease
Which is INCORRECT about the physiologic effects of progesterone?
a. promotes glycogen storage in the liver
b. causes a decrease in Na+ reabsorption
c. decreases basal insulin levels and the insulin response to glucose
d. causes the maturation of the endometrium following ovulation
c. decreases basal insulin levels and the insulin response to glucose
What is the benefit of the use to progestins in combination with estrogens?
a. Prevents uterine bleeding and endometrial carcinoma
b. Prevents acne
c. Prevents breast cancer
d. Increases the efficacy of estrogens
a. Prevents uterine bleeding and endometrial carcinoma
Which of the following statements is INCORRECT about desogestrel?
a. It is a prodrug.
b. It is used for depot injection.
c. It is a 19-nor, 17-ethynyl steroid.
d. It is a progestin.
b. It is used for depot injection.
Which of the following is CORRECT about the physiological effects of glucocorticoids?
a. Increase protein synthesis in muscle
b. Promote the synthesis of cytokines
c. Suppress lipolysis in adipose tissues
d. Inhibit the production of eicosanoids
d. Inhibit the production of eicosanoids
Which of the following is NOT a symptom of Cushing’s disease?
a. Opportunistic infections
b. Osteoporosis
c. Extreme weakness
d. Easy bruising
c. Extreme weakness
A patient has abnormally high levels of ACTH due to pituitary carcinoma. What would be the corresponding effect on the patient’s corticosteroid levels?
a. Increase in cortisol and increase in aldosterone
b. Decrease in cortisol and increase in aldosterone
c. Increase in cortisol and no change in aldosterone
d. Decrease in cortisol and no change in aldosterone
c. Increase in cortisol and no change in aldosterone
Cessation of long-term systemic glucocorticoid therapy can lead to:
a. tumors in the adrenal cortex.
b. Cushing’s symptoms
c. ectopic production of ACTH.
d. Addisonian symptoms.
d. Addisonian symptoms
Which of the following glucocorticoids is a long-acting glucocorticoid?
a. Prednisone
b. Cortisol
c. Dexamethasone
d. Methylprednisolone
c. Dexamethasone
Which of the following corticosteroids is used in the mineralocorticoid replacement therapy?
a. Triamcinolone acetonide
b. Betamethasone
c. Fludrocortisone
d. Prednisone
c. Fludrocortisone
Dexamethasone has a much greater glucocorticoid receptor to mineralocorticoid receptor selectivity than hydrocortisone. What are the structural features responsible for this enhanced SELECTIVITY?
a. Double-bonded oxygen on carbon 3 and double bond between carbons 1 and 2
b. Double-bonded oxygen on carbon 3 and fluorine on carbon 9
c. Double bond between carbons 1 and 2 and fluorine on carbon 9
d. Double bond between carbons 1 and 2 and methyl group on carbon 16
c. Double bond between carbons 1 and 2 and methyl group on carbon 16
Which of the following glucocorticoids is NOT used as an inhaled glucocorticoid?
a. Prednisone
b. Triamcinolone acetonide
c. Fluticasone propionate
d. Flunisolide
a. Prednisone
What is the best description of clobetasol propionate?
a. Inhaled glucocorticoid
b. Topical glucocorticoid
c. Glucocorticoid for intra-articular injection
d. Systemic glucocorticoid
b. Topical glucocorticoid
Which of the following is NOT an adverse effect of glucocorticoids?
a. Moon face
b. Steroid myopathy
c. Hypoglycemia
d. Cataract
c. Hypoglycemia
Which of the following hormones can be used for labor induction?
a. oxytocin
b. prolactin
c. hCG
d. GnRH
a. oxytocin
