EXAM 2 Practice Questions Flashcards
Q) Which of the following is true regarding the adaptive immune response?
a. Develops after exposure
b. Takes a long time to develop
c. It’s only specific to microbes
d. A and B
e. A, B and C
D: A and B (A - Develops after exposure and B - Takes a long time to develop)
The answer does not include C because adaptive immunity can recognize microbes and non-microbes.
Q) What is the outcome when inhibitory receptor on NK cell binds to Class I MHC?
a. NK cell is activated and no cell killing
b. NK cell is not activated and no cell killing
c. NK cell is activated and infected cell gets killed
d. NK cell is not activated and infected cell gets killed
B: NK cell is not activated and no cell killing
Refer to slide 20 (Natural Killer Cells) for the picture.
Q) Match the following immunoglobulin with their roles:
a. IgM – activate complement ; IgA – mucosal immunity ; IgE – mast cell activation
b. IgM – activate complement ; IgA – mast cell activation ; IgE – mucosal immunity
c. IgE – activate complement ; IgG – mucosal immunity ; IgA – mast cell activation
d. IgA – activate complement ; IgM – mucosal immunity ; IgG – mast cell activation
A: IgM – activate complement ; IgA – mucosal immunity ; IgE – mast cell activation
IgG also activates complement
Q) SL is a 24 years old female. She presents to the ER with an anaphylaxis reaction after being stung by a bee. She is experiencing difficulty in breathing. Which type of hypersensitivity is she experiencing?
a. Type I – immediate hypersensitivity
b. Type I – antibody mediated
c. Type III – immune complex-mediated
d. Type IV – cell-mediated
A: Type I – immediate hypersensitivity
Q) Which of the following cellular components of the innate immunity has a tolerogenic function?
a. Macrophages
b. Dendritic cells
c. NK cells
d. Lymphocytes
B: Dendritic cells
Q) PK presents with symptoms of fever and headache which she thought was from a cold. But then the symptoms persisted with a rash and some myalgia. She then remembers that she had gotten an insect bite. Which of the following viruses could be a possible infection?
a. Measles
b. Poliovirus
c. Viral Hemorrhagic Fevers
d. EBV infection
e. None of the above
C: Viral Hemorrhagic Fever
Note: Be careful as this can be confused with Lyme Disease
Q) Viral infections that have a latency or dormant state include:
a. HSV
b. CMV
c. EBV
d. Tb
e. A and B only
f. A, B, and C
F: A, B, and C (HSV, CMV, and EBV)
TB is a Mycobacteria, does have latent period
VZV is a viral infection with latent period (but not in this list)
Q) CO is a 65 years old male who had a history of chicken pox. The doctor’s office recommended getting him vaccinated. Which of the following is NOT true?
a. He should be getting the Shingles vaccine
b. The vaccine will completely prevent the chicken pox from coming back
c. VZV can be latent in him
d. One of the symptoms of VZV reactivation is painful vesicular lesions
B: The vaccine will completely prevent the chicken pox from coming back.
Q) MJ calls the doctor’s office concerned about her 5 months old’s cough. She describes the cough as violent and full of mucous. What would you recommend?
a. Bring the child in for a checkup. It could be pertussis.
b. The cough will go away eventually. There is no treatment for children that young.
c. The child is not contagious and can continue going to daycare.
d. It is probably a staphylococcal infection affecting her respiratory tract.
A: Bring the child in for a checkup. It could be pertussis.
Q) Which of the following viruses is transmitted via the respiratory route?
a. herpes simplex virus 1 (HSV-1)
b. herpes simplex virus 2 (HSV-2)
c. varicella-zoster (VZV)
d. Epstein-Barr virus (EBV)
C: Varicella-zoster (VZV)
Note: EBV is ingested, not transmitted via respiratory route
