Exam 2 - Papillary Lesions

Question 1

T/F HPV is a double stranded RNA virus.

Answer 1

False it is an double stranded DNA virus

Question 2

HPV infects ______ cells. Both cutaneous (face, hands and feet) and mucous membranes (oral cavity. head, neck and anogenital region)

Answer 2

epithelial cells

Question 3

HPV
>____ types in humans
>___ types infect oral mucosa

Answer 3

200;30

Question 4

T/F HPV is associated with benign, potentially malignant, and malignant epithelial lesions.

Answer 4

True

Question 5

HPV Vaccine:

Became routine in ____
Currently ___-valent vaccine
Recommended for adolescent ________ yrs of age
Catch–up vaccine for those under _____
_____ doses ______ months apart

Answer 5

Became routine in 2006
Currently 9-valent vaccine
Recommended for adolescent 11-12 yrs of age
Catch–up vaccine for those under 26
2 doses 6-12 months apart

Question 6

What does the HPV vaccine prevent?

Answer 6

Genital warts
Precancer and cancer of uterine, cervix, vulva, vagina, and anus
Oropharyngeal and other head and neck cancers

Question 7

Oral/head and neck mucosa:

*Oral squamous papilloma HPV

Major HPV type?

Answer 7

HPV 6,11

Question 8

Oral/head and neck mucosa:

*Oropharyngeal squamous cell carcinoma

Major HPV type?

Answer 8

HPV 16

Question 9

Skin

*Verruca vulgaris

Major HPV type?

Answer 9

HPV 2

Question 10

Anogenital region

*Condyloma acuminatum

Major HPV type?

Answer 10

HPV 6,11

Question 11

What category does Squamous Papilloma fall under?

Answer 11

Infectious, neoplastic

Question 12

Name the papillary pathology:

Tend to be stand alone
White or pink exophytic nodule with finger like surface projections
Often pedunculated

Answer 12

Squamous Papilloma

Question 13

What papillary lesions that we talked about have
Benign proliferation/hyperplasia of stratified squamous?

Answer 13

1. Squamous Papilloma
2. Verruca Vulgaris
3. Condyloma Acuminatum

Can be difficult to differentiate from one another

Question 14

What are common locations to find Squamous Papilloma?

Answer 14

Soft palate, tongue, and lips are common oral sites

Question 15

What age are squamous papillomas most likely to be found?

Answer 15

30-50 yrs olde

Question 16

How do you tx squamous Papilloma?

Answer 16

Excisional biopsy
Tend to have a narrow base great practice for biopsying
LOW recurrence

Question 17

What category does Verruca Vulgaris “common wart” fall under?

Answer 17

Infectious, neoplastic

Question 18

T/F Verruca Vulgaris “common wart” is contagious.

Answer 18

TRUE!

Question 19

What age group are you most likely to find Verruca Vulgaris?

Answer 19

Children

Question 20

Name the lesion

Painless papule with papillary projections or rough, pebbly surface
Can have multiple or clustered lesions
Contagious

Answer 20

Verruca Vulgaris “common wart”

Question 21

Where is Verruca Vulgaris “common wart” most commonly found?

Skin -

Orally -

Answer 21

Skin - hands

Orally - vermillion border, labial mucosa, and anterior tongue

Question 22

How do you tx Verruca Vulgaris “common wart” on the skin?

Answer 22

Topical salicylic acid
Cryotherapy

Question 23

How do you tx Verruca Vulgaris “common wart” orally?

Answer 23

Cryotherapy
Surgical excision (first line tx for oral lesions)

Question 24

T/F Verruca Vulgaris “common wart” can resolve spontaneously.

Answer 24

True (2/3rd resolve within 2 years)

Question 25

How long does it take for Verruca Vulgaris “common wart” to resolve spontaneously

Answer 25

2/3rd resolve within 2 years

Question 26

What category does Condyloma Acuminatum fall under

Answer 26

Infectious - b/c thought of as a sexually transmitted disease

Question 27

T/F Condyloma Acuminatum is contagious.

Answer 27

True

Question 28

What papillary lesion did we talked about that is a common sedxually transmitted disease?

Answer 28

Condyloma Acuminatum

Question 29

What demographic is Condyloma Acuminatum commonly found in?

Answer 29

Teenager and young adults

Question 30

Condyloma Acuminatum is most commonly found __________.

Answer 30

Anogenital

Question 31

Where are Condyloma Acuminatum lesions most frequently found orally?

Answer 31

labial mucosa and lingual frenum

Question 32

Name the lesion: Sessile, pink, exophytic mass with short, blunted surface projections Tend to be larger than squamous papillomas May be single or clustered

Answer 32

Condyloma Acuminatum

Question 33

T/F Condyloma acuminatum is only found solitary.

Answer 33

False can be clustered or single

Question 34

How do you tx Condyloma Acuminatum

Answer 34

Excisional biopsy Cryotherapy and laser ablation also used

Question 35

What category does inflammatory papillary hyperplasia fall under?

Answer 35

Injury

Question 36

Describe etiology of Inflammatory papillary hyperplasia

Answer 36

Ill-fitting denture Poor denture hygiene Wearing denture 24 hours a day

Question 37

Besides denture wearers Inflammatory papillary hyperplasia can also occur in pt with .....

Answer 37

high palatal vault and mouth breathers

Question 38

Name the lesion: Usually asymptomatic Erythematous pebbly or papillary mucosa Some have candidiasis some may not

Answer 38

Inflammatory papillary hyperplasia

Question 39

How do you tx Inflammatory papillary hyperplasia?

Answer 39

Improve denture hygiene/remake ill-fitting denture Topical and or systemic antifungal if indicated