Exam 2 Pancreas Flashcards
What 5 peptide hormones are secreted by the pancreas
- insulin
- glucagon
- somatostatin
- pancreatic polypeptide
- ghrelin
What type of cells is insulin
Beta cells
What type of cells is glucagon
Alpha cells
What do insulin and glucagon do together
Function in coordinated way to regulate glucose, fatty acid, and amino acid metabolism
What type of cells is somatostatin
S cells
What type of cells is pancreatic polypeptide
F cells
Where is ghrelin produced
Major site of production is in the stomach
What effect does ghrelin have
The hunger signal - Signals the hypothalamus to promote food intake
What are the islets of Langerhans
Endocrine cells of pancreas are arranged in clusters that make up 1-2% of pancreatic mass
Where and what do alpha cells do in the pancreas
20% of pancreas secreting glucagon located in the outer rim
Where and what do beta cells do in the pancreas
65% of pancreas secreting insulin and are located in the central core
Where and what do S cells do in the pancreas
Makeup 10% of pancreas secreting somatostatin and are interspersed
Where and what do F cells do in the pancreas
5% of pancreas secreting pancreatic polypeptide
What do gap junctions connect in paracrine communication islet cells
- a to a
- B to B
- a to B
What is the blood supply arrangement in islet cells
Arranged so venous blood of one cell type bathes the other cell type
