Exam 2 - Endorphins & Substance P Flashcards

1
Q

endorphins are produced in these two areas

A

CNSs & pituitary

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2
Q

Role of endorphins

A

inhibit transmission of pain

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3
Q

influences emotional and physical pain perception

A

enkelphalins

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4
Q

can have an effect on mood and well being

A

endorphins

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5
Q

endorphins are released when the body goes from an ____ to ____ state

A

aerobic, anaerobic

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6
Q

site and synthesis of substance P

A

CNS, PNS, neuropeptide

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7
Q

Role of Substance P

A

Neurotransmitter that Binds to neurokinin-1 receptor transmitting pain and found in all organs

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8
Q

Other role of substance P besides pain

A

increases HR**, vasodilates decreasing BP, increases immune response

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9
Q

areas that substance P affects with inflammatory diseases

A

respiratory, GI, musculoskeletal system

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10
Q

inflammatory diseases from substance P

A

eczema, fibromyalgia, low back pain, arthritis

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11
Q

2 locations where oxytocin is produced

A

supraoptic nucleus and paraventricular nuclei of the hypothalamus

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12
Q

primary function of oxytocin

A

stimulate milk release, stimulate parturition, stimulate uterine shrinkage- after birth

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13
Q

secondary function of oxytocin

A

increase renal reabsorption of water

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14
Q

neurological control of oxytocin

A

nerve impulses in the uterus myometrium OT stimulates smooth muscle contraction

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15
Q

oxytocins other benefits than being just a love hormone

A

improves work place bonding, reduces stress and anxiety, may improve social functioning in autism

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16
Q

role of oxytocin in bulimia nervosa

A

it is implicated in the modulation of reward, reduces the intake of high sugar snacks

17
Q

Epigenetic modification of oxytocin receptor gene influences the perception of anger and fear in human beings an can affect this

A

social behavior

18
Q

other names for ADH

A

vasopressin, arginine vasopressin, argipressin

19
Q

site of synthesis for ADH

A

supra-optic nucleus of hypothalamus

20
Q

where is ADH secreted

A

posterior pituitary

21
Q

primary function of ADH

A

regulate body’s retention of water

22
Q

physiological actions of ADH

A

blood pressure and blood volume

23
Q

disease causing decreased output of ADH and increased urine output (polyuria) leading to excessive thirst

A

central diabetes insipidus

24
Q

two causes of central diabetes insipidus

A

insufficient release of ADH by hypothalamus or pituitary

25
Q

physical characteristics of central diabetes insipidus

A

polyuria, decreased urine concentration, hypotension (decreased plasma volume)

26
Q

how does the body compensate for central diabetes insipidus

A

increased aldesterone secretion causing renal reabsorption of NA and excretion of hydrogen and potassium ions - brings BP back to normal

27
Q

where is aldosterone produced

A

adrenal cortex

28
Q

eitologic disease of the kidneys causing polyuria, dilute urine, hypotension, and increased plasma concentration

A

nephrogenic diabetes insipidus

29
Q

causes of nephrogenic diabetes insipidus

A

kidneys fail to respond to ADH and cannot concentrate urine, pituitary gland secretes ADH but kidneys to do not respond to signal

30
Q

drug that can cause NDI

A

lithium

31
Q

complications of fluid overload in patients

A

strokes, head trauma, brain tumors

32
Q

disease where large amounts of ADH are released

A

syndrome of inappropriate antidiuretic hormone secretion (SIAHD)

33
Q

Disease where there is an excessive bulidup of fluids as well as abnormally low sodium levels

A

hyponatremia