Exam 2 - Endorphins & Substance P Flashcards

1
Q

endorphins are produced in these two areas

A

CNSs & pituitary

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2
Q

Role of endorphins

A

inhibit transmission of pain

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3
Q

influences emotional and physical pain perception

A

enkelphalins

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4
Q

can have an effect on mood and well being

A

endorphins

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5
Q

endorphins are released when the body goes from an ____ to ____ state

A

aerobic, anaerobic

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6
Q

site and synthesis of substance P

A

CNS, PNS, neuropeptide

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7
Q

Role of Substance P

A

Neurotransmitter that Binds to neurokinin-1 receptor transmitting pain and found in all organs

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8
Q

Other role of substance P besides pain

A

increases HR**, vasodilates decreasing BP, increases immune response

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9
Q

areas that substance P affects with inflammatory diseases

A

respiratory, GI, musculoskeletal system

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10
Q

inflammatory diseases from substance P

A

eczema, fibromyalgia, low back pain, arthritis

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11
Q

2 locations where oxytocin is produced

A

supraoptic nucleus and paraventricular nuclei of the hypothalamus

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12
Q

primary function of oxytocin

A

stimulate milk release, stimulate parturition, stimulate uterine shrinkage- after birth

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13
Q

secondary function of oxytocin

A

increase renal reabsorption of water

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14
Q

neurological control of oxytocin

A

nerve impulses in the uterus myometrium OT stimulates smooth muscle contraction

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15
Q

oxytocins other benefits than being just a love hormone

A

improves work place bonding, reduces stress and anxiety, may improve social functioning in autism

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16
Q

role of oxytocin in bulimia nervosa

A

it is implicated in the modulation of reward, reduces the intake of high sugar snacks

17
Q

Epigenetic modification of oxytocin receptor gene influences the perception of anger and fear in human beings an can affect this

A

social behavior

18
Q

other names for ADH

A

vasopressin, arginine vasopressin, argipressin

19
Q

site of synthesis for ADH

A

supra-optic nucleus of hypothalamus

20
Q

where is ADH secreted

A

posterior pituitary

21
Q

primary function of ADH

A

regulate body’s retention of water

22
Q

physiological actions of ADH

A

blood pressure and blood volume

23
Q

disease causing decreased output of ADH and increased urine output (polyuria) leading to excessive thirst

A

central diabetes insipidus

24
Q

two causes of central diabetes insipidus

A

insufficient release of ADH by hypothalamus or pituitary

25
physical characteristics of central diabetes insipidus
polyuria, decreased urine concentration, hypotension (decreased plasma volume)
26
how does the body compensate for central diabetes insipidus
increased aldesterone secretion causing renal reabsorption of NA and excretion of hydrogen and potassium ions - brings BP back to normal
27
where is aldosterone produced
adrenal cortex
28
eitologic disease of the kidneys causing polyuria, dilute urine, hypotension, and increased plasma concentration
nephrogenic diabetes insipidus
29
causes of nephrogenic diabetes insipidus
kidneys fail to respond to ADH and cannot concentrate urine, pituitary gland secretes ADH but kidneys to do not respond to signal
30
drug that can cause NDI
lithium
31
complications of fluid overload in patients
strokes, head trauma, brain tumors
32
disease where large amounts of ADH are released
syndrome of inappropriate antidiuretic hormone secretion (SIAHD)
33
Disease where there is an excessive bulidup of fluids as well as abnormally low sodium levels
hyponatremia