Exam 2 Drugs Flashcards

1
Q

Glycopyrrolate

A

Direct muscarinic antagonist

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2
Q

atropine

A

Direct muscarinic antagonist

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3
Q

Tolterodine

A

Direct muscarinic antagonist

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4
Q

Ipatropium

A

Direct muscarinic antagonist (bronchodilator)

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5
Q

ACh

A

Direct cholinergic neurotransmitter

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6
Q

Methacholine

A

Direct muscarinic agonist (additional methyl group on ACh)

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7
Q

Bethanechol

A

Direct muscarinic agonist (NH2 and methyl substitution on ACh)

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8
Q

Pilocarpine

A

Direct muscarinic agonist

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9
Q

muscarine

A

Direct muscarinic agonist

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10
Q

Edrophonium

A

Cholinergic Indirect acting agonist (AChE inhibitor)

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11
Q

Physostigmine

A

Nicotinic Indirect acting agonist (reversible AChE Inhibitor)

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12
Q

Neostigmine

A

Nicotinic Indirect acting agonist

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13
Q

Malathion (insecticide)

A

Nicotinic Indirect acting agonist

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14
Q

Nerve Gas

A

Nicotinic Indirect acting agonist (irreversibly blocks AChE)

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15
Q

What do you give to someone with Nerve gas poisoning?

A

Atropine and 2 PAM pralidoxime

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16
Q

Nicotine

A

Nicotinic agonist/antagonist

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17
Q

Succinlycholine

A

Nicotinic agonist/antagonist

18
Q

Trimethaphan

A

Nicotinic antagonist/ganglionic blocker (antihypertensive use)

19
Q

Atracurium

A

Nicotinic antagonist/ND NMB

20
Q

Pancuronium

A

Nicotinic antagonist/ND NMB

21
Q

Rocuronium

A

Nicotinic antagonist/ND NMB

22
Q

Curare

A

Nicotinic antagonist/ND NMB

23
Q

Phenylephrine

A

Alpha 1 direct agonist

24
Q

NE

A

Alpha and Beta direct agonist (greatest affinity for alpha 1)

25
Q

Epi

A

direct agonist Alpha and Beta (B>A)

26
Q

Isoproternal (used to treat bradycardia)

A

Beta agonist (1=2)

27
Q

Dobutamine (assists in Heart contractility)

A

Beta agonist (1>2»>A)

28
Q

Albuterol

A

Beta agonist (2»1»»A)

29
Q

Amephetamine

A

Indirect Alpha/Beta agonist (releasing agent)

30
Q

Ephedrine

A

Indirect Alpha/Beta agonist (A1 = A2; B1=B2>A1)

31
Q

Reserpine

A

Indirect antagonist for Alpha/Beta

32
Q

Cocaine

A

Indirect agonist for Alpha/Beta (Uptake Inhibitor)

33
Q

Clonodine

A

Direct alpha 2 agonist

34
Q

Dexmedetomidate

A

Direct Alpha 2 agonist (sedative w/o decreasing respiration)

35
Q

Doxazosin

A

Indirect Alpha 1 antagonist (used to treat hypertension)

36
Q

Labetalol

A

Beta/alpha antagonist (B1-2 > A1&raquo_space;>A2)

will reduce HR and cause bronchoconstriction

37
Q

Metoprolol (used to treat angina and hypertension)

A

Direct Beta antagonist (B1&raquo_space;> B2)

38
Q

Propanolol

A

Beta antagonist (B1=B2) beta blocker

39
Q

Tetredotoxin

A

Indirect Antagonist for all Na+ channels

40
Q

Conotoxin

A

Indirect Antagonist for all Ca++ channels

41
Q

Botulinum toxin

A

Indirect nicotinic antagonist