Exam 2 Drugs

Question 1

Glycopyrrolate

Answer 1

Direct muscarinic antagonist

Question 2

atropine

Answer 2

Direct muscarinic antagonist

Question 3

Tolterodine

Answer 3

Direct muscarinic antagonist

Question 4

Ipatropium

Answer 4

Direct muscarinic antagonist (bronchodilator)

Question 5

ACh

Answer 5

Direct cholinergic neurotransmitter

Question 6

Methacholine

Answer 6

Direct muscarinic agonist (additional methyl group on ACh)

Question 7

Bethanechol

Answer 7

Direct muscarinic agonist (NH2 and methyl substitution on ACh)

Question 8

Pilocarpine

Answer 8

Direct muscarinic agonist

Question 9

muscarine

Answer 9

Direct muscarinic agonist

Question 10

Edrophonium

Answer 10

Cholinergic Indirect acting agonist (AChE inhibitor)

Question 11

Physostigmine

Answer 11

Nicotinic Indirect acting agonist (reversible AChE Inhibitor)

Question 12

Neostigmine

Answer 12

Nicotinic Indirect acting agonist

Question 13

Malathion (insecticide)

Answer 13

Nicotinic Indirect acting agonist

Question 14

Nerve Gas

Answer 14

Nicotinic Indirect acting agonist (irreversibly blocks AChE)

Question 15

What do you give to someone with Nerve gas poisoning?

Answer 15

Atropine and 2 PAM pralidoxime

Question 16

Nicotine

Answer 16

Nicotinic agonist/antagonist

Question 17

Succinlycholine

Answer 17

Nicotinic agonist/antagonist

Question 18

Trimethaphan

Answer 18

Nicotinic antagonist/ganglionic blocker (antihypertensive use)

Question 19

Atracurium

Answer 19

Nicotinic antagonist/ND NMB

Question 20

Pancuronium

Answer 20

Nicotinic antagonist/ND NMB

Question 21

Rocuronium

Answer 21

Nicotinic antagonist/ND NMB

Question 22

Curare

Answer 22

Nicotinic antagonist/ND NMB

Question 23

Phenylephrine

Answer 23

Alpha 1 direct agonist

Question 24

NE

Answer 24

Alpha and Beta direct agonist (greatest affinity for alpha 1)

Question 25

Epi

Answer 25

direct agonist Alpha and Beta (B>A)

Question 26

Isoproternal (used to treat bradycardia)

Answer 26

Beta agonist (1=2)

Question 27

Dobutamine (assists in Heart contractility)

Answer 27

Beta agonist (1>2>>>A)

Question 28

Albuterol

Answer 28

Beta agonist (2>>1>>>>A)

Question 29

Amephetamine

Answer 29

Indirect Alpha/Beta agonist (releasing agent)

Question 30

Ephedrine

Answer 30

Indirect Alpha/Beta agonist (A1 = A2; B1=B2>A1)

Question 31

Reserpine

Answer 31

Indirect antagonist for Alpha/Beta

Question 32

Cocaine

Answer 32

Indirect agonist for Alpha/Beta (Uptake Inhibitor)

Question 33

Clonodine

Answer 33

Direct alpha 2 agonist

Question 34

Dexmedetomidate

Answer 34

Direct Alpha 2 agonist (sedative w/o decreasing respiration)

Question 35

Doxazosin

Answer 35

Indirect Alpha 1 antagonist (used to treat hypertension)

Question 36

Labetalol

Answer 36

Beta/alpha antagonist (B1-2 > A1 >>>A2) | will reduce HR and cause bronchoconstriction

Question 37

Metoprolol (used to treat angina and hypertension)

Answer 37

Direct Beta antagonist (B1 >>> B2)

Question 38

Propanolol

Answer 38

Beta antagonist (B1=B2) beta blocker

Question 39

Tetredotoxin

Answer 39

Indirect Antagonist for all Na+ channels

Question 40

Conotoxin

Answer 40

Indirect Antagonist for all Ca++ channels

Question 41

Botulinum toxin

Answer 41

Indirect nicotinic antagonist