Exam 2 drugs Flashcards
sodium bicarbonate
reduce and protect against peptic acid Group: antacid Class: weak base MOA: neutralizes peptic acid Use: oral ADR: metabolic alkalosis, belching
calcium carbonate
reduce and protect against peptic acid Group: Antacid Class: Weak base MOA: Neutralizes peptic acid Use: Oral ADR: metabolic alkalosis, hypercalcemia, renal insufficiency with high doses with dairy products
aluminum hydroxide
reduce and protect against peptic acid Group: antacid Class: weak base MOA: neutralizes peptic acid Use: Oral ADR: Constipation
magnesium hydroxide
reduce and protect against peptic acid Group: antacid Class: Weak base MOA: neutralizes peptic acid Uses: oral ADR: diarrhea
cimetidine
reduce and protect against peptic acid
Group: Acid reducer
Class: H2RA
MOA: inhibits H2 receptors
Use: ORal; IV for stress related bleeding
ADR: long-term/high doses: gynecomastia, impotence in men; galactorrhea in women. DO NOT use in pregnant or breastfeeding women
omeprazole
reduce and protect against peptic acid Group: acid reducer Class: PPI MOA: inhibits proton pump (H+) Use: oral ADR: increased risk of infection due to reduced acid (esp C. diff)
bismuth subsalicylate
reduce and protect against peptic acid
Group: protection from acid
Class: Mucosal protective agent
MOA: coats ulcers and erosions forming a protective layer
Use: Oral
ADR: possible bismuth and subsalicylate toxicity
bethanechol
GI motility stimulating drugs Group: cholinomimetic agonist Class: cholinergic MOA: increase motility by activating ACh and M3 receptors Use: Oral ADR:
neostigmine
GI motility stimulating drugs
Group: cholinomimetic agonist
Class: acetylcholinesterase inhibitor
MOA: increases motility by decreasing breakdown of ACh
metoclopramide
GI motility stimulating drugs
erythromycin
GI motility stimulating drugs
psyllium
Laxative/Cathartic
docusate
Laxative/Cathartic
magnesium hydroxide (milk of magnesia)
Laxative/Cathartic
sorbitol
Laxative/Cathartic
