Exam 2 Drugs

Question 1

Fluoxetine

Answer 1

SSRI
Also for menopause symptoms like hot flash if you can tolerate restlessness, insomnia, activation, etc

Question 2

Sertraline

Answer 2

SSRI
Works for people needing more sleep (sedating properties)
GI distress but some bypass it because sleeping is comfortable

Question 3

Paroxetine

Answer 3

SSRI
Most anticholinergic

Question 4

Citalopram

Answer 4

SSRI
For QT prolongation, check for electrolyte disturbances

Question 5

Escitalopram

Answer 5

SSRI

Question 6

Fluvoxamine

Answer 6

SSRI
Not prescribed as much as others, newer, nice combo of all side effects
Since it’s newer, people don’t really want to use it

Question 7

Vilazodone

Answer 7

SPARI
More neutral in terms of SE profile since it’s an agonist and antagonist
Dual activity makes this a SPARI

Question 8

Venlafaxine

Answer 8

SNRI
Menopausal and antidepressant
Oldest

Question 9

Desvenlafaxine

Answer 9

SNRI

Question 10

Duloxetine

Answer 10

SNRI
menopausal and antidepressant
oldest

Question 11

Levomilnacipran

Answer 11

SNRI
One of the newest newer ones
Not as many people using it

Question 12

Nefazodone

Answer 12

SARI
formerly sold as Serzone

Question 13

Trazodone

Answer 13

SARI
formerly sold as Desyrel, Oleptro

Question 14

Brexpiprazole

Answer 14

SARI
rexulti
Newer

Question 15

Vilazodone

Answer 15

SARI
Viibryd
Newer

Question 16

Vortioxetine

Answer 16

SARI
Trintellix
Newer

Question 17

Mirtazapine

Answer 17

Norepinephrine and serotonin-specific antidepressant
Remeron

Question 18

Bupropion

Answer 18

Norepinephrine dopamine reuptake inhibitor
Also known as wellbutrin (trade name)
Also known as zyban (rebranded for smoking cessation)

Question 19

Nortriptyline

Answer 19

Tricyclic
Pamelor

Question 20

Amitriptyline

Answer 20

Tricyclic
Elavil

Question 21

Imipramine

Answer 21

Tricyclic
Tofranil

Question 22

Isocarboxazid

Answer 22

MAOI
Marplan

Question 23

Phenelzine

Answer 23

MAOI
Nardil

Question 24

Selegiline

Answer 24

MAOI
EMSAM
Patch bypasses other symptoms so less dietary issues. Some people do this first but others may not because they’re not familiar with it

Question 25

Tranylcypromine

Answer 25

MAOI
Parnate

Question 26

Esketamine

Answer 26

Sparato
Nasal spray for treatment of resistant depression-schedule III drug
Ketamine used for chronic regional pain syndrome (CRPS), works for 2h
Works for depression for 24h and then depression comes back. Rebranded as esketamine

Question 27

Brexanolone

Answer 27

1st and only FDA approved med for ppd- schedule II drug
Neuroactive steroid 60 hour IV infusion. It is a one time infusion.

Question 28

Brexanolone SE

Answer 28

hypoxia, excessive sedation, and potential LOC. patients are continuously monitored

Question 29

Lithium carbonate use and levels

Answer 29

Bipolar I
use this, then another mood stabilizer, then add an antipsychotic or depakote
0.8-1.2
Toxic is 1.5+
Maintenance: 0.6-0.8

Question 30

What to monitor with lithium

Answer 30

Renal and thyroid

Question 31

How long does lithium take to work

Answer 31

Takes 3 days to 3 weeks to work

Question 32

Anticonvulsant mood stabilizers

Answer 32

valproate, carbamazepine (6-12), and lamotrigine

Question 33

Anti anxiety meds

Answer 33

clonazepam and lorazepam

Question 34

Antipsychotics-Atypicals-second generation

Answer 34

Olanzapine and risperidone

Question 35

Typical-first gen antipsychotics

Answer 35

chlorpromazine and loxapine
Works for aggression, calms them down

Question 36

Valproic acid

Answer 36

May work quickly for aggressive pt
Levels 50-100

Question 37

Order of meds for bipolar

Answer 37

First line is lithium, second line is antipsychotic or depakote if they don’t want that
If they don’t want lithium or have renal issues, they would go on other mood stabilizer like depakene

Question 38

Lamotrigine SE

Answer 38

bad rash, 5 weeks into therapy, d/c it once this happens and find another medication

Question 39

Lithium dosage

Answer 39

900-1800 mg daily in 2-4 divided doses
max 2400 daily