Exam 2 Drugs Flashcards
Fluoxetine
SSRI
Also for menopause symptoms like hot flash if you can tolerate restlessness, insomnia, activation, etc
Sertraline
SSRI
Works for people needing more sleep (sedating properties)
GI distress but some bypass it because sleeping is comfortable
Paroxetine
SSRI
Most anticholinergic
Citalopram
SSRI
For QT prolongation, check for electrolyte disturbances
Escitalopram
SSRI
Fluvoxamine
SSRI
Not prescribed as much as others, newer, nice combo of all side effects
Since it’s newer, people don’t really want to use it
Vilazodone
SPARI
More neutral in terms of SE profile since it’s an agonist and antagonist
Dual activity makes this a SPARI
Venlafaxine
SNRI
Menopausal and antidepressant
Oldest
Desvenlafaxine
SNRI
Duloxetine
SNRI
menopausal and antidepressant
oldest
Levomilnacipran
SNRI
One of the newest newer ones
Not as many people using it
Nefazodone
SARI
formerly sold as Serzone
Trazodone
SARI
formerly sold as Desyrel, Oleptro
Brexpiprazole
SARI
rexulti
Newer
Vilazodone
SARI
Viibryd
Newer
Vortioxetine
SARI
Trintellix
Newer
Mirtazapine
Norepinephrine and serotonin-specific antidepressant
Remeron
Bupropion
Norepinephrine dopamine reuptake inhibitor
Also known as wellbutrin (trade name)
Also known as zyban (rebranded for smoking cessation)
Nortriptyline
Tricyclic
Pamelor
Amitriptyline
Tricyclic
Elavil
Imipramine
Tricyclic
Tofranil
Isocarboxazid
MAOI
Marplan
Phenelzine
MAOI
Nardil
Selegiline
MAOI
EMSAM
Patch bypasses other symptoms so less dietary issues. Some people do this first but others may not because they’re not familiar with it
Tranylcypromine
MAOI
Parnate
Esketamine
Sparato
Nasal spray for treatment of resistant depression-schedule III drug
Ketamine used for chronic regional pain syndrome (CRPS), works for 2h
Works for depression for 24h and then depression comes back. Rebranded as esketamine
Brexanolone
1st and only FDA approved med for ppd- schedule II drug
Neuroactive steroid 60 hour IV infusion. It is a one time infusion.
Brexanolone SE
hypoxia, excessive sedation, and potential LOC. patients are continuously monitored
Lithium carbonate use and levels
Bipolar I
use this, then another mood stabilizer, then add an antipsychotic or depakote
0.8-1.2
Toxic is 1.5+
Maintenance: 0.6-0.8
What to monitor with lithium
Renal and thyroid
How long does lithium take to work
Takes 3 days to 3 weeks to work
Anticonvulsant mood stabilizers
valproate, carbamazepine (6-12), and lamotrigine
Anti anxiety meds
clonazepam and lorazepam
Antipsychotics-Atypicals-second generation
Olanzapine and risperidone
Typical-first gen antipsychotics
chlorpromazine and loxapine
Works for aggression, calms them down
Valproic acid
May work quickly for aggressive pt
Levels 50-100
Order of meds for bipolar
First line is lithium, second line is antipsychotic or depakote if they don’t want that
If they don’t want lithium or have renal issues, they would go on other mood stabilizer like depakene
Lamotrigine SE
bad rash, 5 weeks into therapy, d/c it once this happens and find another medication
Lithium dosage
900-1800 mg daily in 2-4 divided doses
max 2400 daily
