Exam 2: de Villiers Excipients Flashcards

1
Q

Sodium lauryl sulfate

A

Surfactant

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2
Q

Microcrystalline cellulose

A

Tablet diluent

Used for direct compression

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3
Q

Magnesium stearate

A

Lubricant (not soluble in water)

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4
Q

PVP or Povidone

A

Binder

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5
Q

Dicalcium phosphate

A

Diluent for tablet (not water soluble)

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6
Q

Corn starch

A

Binder
Disintegrant
Diluent

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7
Q

Croscarmellose sodium

A

Super disintegrant

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8
Q

Sodium starch glycolate

A

Super disintegrant

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9
Q

Colloidal silicon dioxide

A

Glider

Dessicant (drying agent)

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10
Q

Methyl paraben

A

Preservative

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11
Q

Gelatin

A

Binder

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12
Q

Propyl paraben

A

Preservative

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13
Q

Sodium benzoate

A

Preservative

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14
Q

Talc

A

Lubricant

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15
Q

Benzalkonium bromide

A

Preservative for injection

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16
Q

Potassium sorbate

A

Preservative

17
Q

Sucrose

A

Sweetener

Diluent

18
Q

Xanthan Gum

A

Binder
Thickener
Alternative for gelatin

19
Q

Carbomer

A

Gelling agent

Suspending agent

20
Q

Calcium stearate

A

Lubricant (not water soluble)

21
Q

Sodium saccharin

A

Sweetener

22
Q

Aspartamine

A

Sweetener

23
Q

Stearic acid

A

Lubricant (more soluble in water)

Emulsifier

24
Q

Sucralose

A

Sweetener

25
Q

Mannitol

A

Diluent

Sweetener (can be alternative to other compressioner, more water soluble)

26
Q

Titanium dioxide

A

White pigment (not water soluble)

27
Q

Sorbitol

A

Plasticizer
Sugar alternative
Laxative and osmotic agent (at higher concentrations)

28
Q

Tween 80 or Polysorbate 80

A

Emulsifier

29
Q

HPMC

A

Gelatin alternative

Excipient in controlled release

30
Q

Ferric oxide

A

Red dye

31
Q

Sodium bicarbonate

A

Alkalyzing agent

32
Q

EDTA or Ethylene diamine (tetraacetic acid)

A

Chelator

33
Q

Organic diluents

A
Starch
Lactose
Mannitol
Microcrystalline cellulose
Methyl cellulose
34
Q

Inorganic diluent

A

Kaolin
Bentonite
CaCO3 (dilatant)
Dicalcium phosphate