Exam 2 - CV And Resp Flashcards

1
Q

Decongestants: pseudoephedrine* (Sudafed), oxymetazoline (Afrin)

A
  • r/t Rhinitis (nasal congestion)
  • Vasoconstriction of respiratory tract mucosa
  • SE: Rebound congestion (if over used), tachycardia, dizziness, heart muscle irritability, restlessness
  • Careful for clients w/ hypertension.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

dextromethorphan (Robitussin DM, etc)

A
  • Anti-tussives r/t dry cough
  • Suppresses cough reflex in the medulla oblongata and respiratory system by elevating cough threshold
  • SE: Dizziness, sedation w/ high dose, interacts w/ antidepressants (serotonin syndrome)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

guaifenesin (Mucinex)

A
  • Expectorants r/t non-productive cough w/ respiratory infections
  • thins secretions, making coughs more productive to cough up.
  • SE: GI upset (N/V/D), dizziness, dry mouth, kideny stones
  • Take w/ food, ^ fluids
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Antihistamines: diphenhydramine (Benadryl)*, loratadine (Claritin)

A
  • r/t allergic Sx (rhinitis, itchy/water eyes, sneezing), motion sickness/vertigo, itchy rash, nausea, Parkinson’s
  • Inhibits H1 receptors, reducing effects of histamine
  • SE: Anticholinergic affects, sedating
  • Take w/ food.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

epinephrine (EpiPen) IV, albuterol (Proventil)*

A
  • neb
  • Bronchodilators Adrenergic r/t Asthma, COPD
  • stimulates beta 2 receptors in airway smooth muscle, causing bronchodilation + phasoconstriction
  • SE: tachycardia
  • Teach to always carry as it is “rescue medication”
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

ipratropium (Atrovent)

A
  • Bronchodilators Anticholinergics r/t COPD (chronic bronchitis, emphysema), rhinitis, asthma, combine w/ albuterol (Duoneb) + combiven meter-dose inhaler on schedule
  • Maintenance inhaler - blocks ACh receptors (parasympathetic stimulation) of respiratory tract - bronchodilation.
  • SE: Anticholinergic (decreased tachycardia affects)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

montelukast* (Singulair)

A
  • Leukotriene Antagonist r/t asthma + prevention bronchoconstriction
  • Decrease Leukotrienes, reducing airway inflammation w/ prostoglandins to cause bronchodilation and decrease mucus production.
  • SE: HA, very fiew so can be taken by kids
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

fluticasone (Flonase OTC, Flovent)

A
  • Inhaled Corticosteroids r/t asthma, rhinitis (nasal congestion)
  • Maintenance therapy only, decreases inflammation w/ limited systemic effects
  • SE: HA, oral candidiasis (Fungal infection), pharyngitis (sore throat), cough, dry mouth/nostrils
  • Rinse mouth after administration + spit , use bronchodilator first > wait 5 min, then use.
  • Adavai (fluticasone, salmeterol (broncho)), long acting taken on a schedule once in morning and night to keep symptoms under control.
  • Symbicort (budesonide (cortico), formoterol (adrenergic agonist, broncho))
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

captopril (Capoten), lisinopril* (Zestril)

A
  • Ace Inhibitor Antihypertensive r/t hypertension, CHF (in smaller doses), kidney protective for diabetic pts
  • Blocks ACE enzymes from conversion of angiotensin I to angiotensin II, allow vasodilation + Na and H2O release.
  • SE: Hypotension, hyperkalemia, dry cough
  • Monitor: BP before administration (Hold <100/60), check K+ serum levels.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

losartan (Cozaar)

A
  • can use w/ diuretic Antihypertensive
  • Angiotensin II Receptor Blockers (ARBs) r/t Hypertension, diabetic nephropathy, CHF
  • Blocks action of angiotensin II binding on smooth muscle, resulting in vasodilation as Na+ and H2O release (diuresis) w/ K+ sparing
  • SE: Hypotension, dizziness, GI upset, hyperkalmia
  • Monitor BP + k+ serum levels
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

atenolol (Tenormin)

A
  • metroprolol (lopressor, toprol): Selective - Blocks beta 1 (heart) adrenergic receptors
  • carvedilo (Coreg): non-selective - blocks beta 1 + 2 (Lungs)
  • Antihypertensive (respiratory), Beta Blockers (Beta Adrenergic Antagonists): r/t Hypertension, Angina, tachy arrhythmias, cardio protective
  • Decreases BP + HR w/ vasodilation, bronchoconstriction
  • SE: Bronchospasm (asthma/COPD should avoid), hypotension, bradycardia, fatigue, constipation, orthostatic hypotension
  • Monitor BP (hold on SBP <100) and apical pulse (Hold on <60 bpm) + for respiratory effects w/ non-selective betal blockers 2
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

nifedipine (Procardia), amlopidine (Norvasc)

A
  • Antihypertensive, Calcium Channel Blockers r/t angina, hypertension, tachy arrhythmias
  • blocks calcium channels in blood vessels + heart (making less excitable), cause vasodilation (decreased contractability), decreased HR and BP
  • SE: peripheral edema, hypotension, bradycardia, HA, constipation
  • Monitor: hold if BP (SBP <100) + AP (<60 bpm), avoid caffeine + changing positions slowly, notify if weight gain.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Acetazolamide (Diamox)*

A
  • Carbonic Anhydrase Inhibitors [diuretics] r/t glaucoma, edema, high-altitude sickness, CHF
  • Inhibit hydrogen ion formation to stop resportion of Na+, H20, chloride ions @ proximal tubule (70% resorption) as there is no hydrogen to exchange.
  • SE: drowsiness, hyperchloremic acidosis (^ respiration), electrolyte imbalance (Na + K), photosensitivity, hypokalemia
  • Contraindicated: allergies to sulfa, liver/renal failure
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

furosemide (Lasix)*

A
  • Loop Diuretic r/t edema, liver disease, hypertension
  • Blocks reabsorption of Na, Cl, and H20 in the ascending loop of Henle (20-25%), causing rapid potent diuresis (effective in renal impairment)
  • SE: electrolyte imbalances (hyopkalemia- k wasting often need supplements)
  • Contra: sulfa allergy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

hydrochlorothiazide* (HCTZ - Microzide)

A

-Thiazide Diuretics
- r/t first line med for HTN, edema, heart failure, diabetes, siffidus (concentrate to dilute urine), not as good for decreased renal function.
- blocks reabsoprtion of Na, Cl, + H20 at distal convoluted tubule (~5%) leading to osmotic water loss.
> decrease Ca to increase Ma
- SE: hypokalemia (K wasting) but not much need for supplements

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

mannitol (Osmitrol)

A
  • (IV) Osmotic Diuretics r/t cerebral edema, ^ intraocular pressure (ICP), early acute renal failure, ^ intracrandial pressure (IOP)
  • Reducing ICP + IOP by ^ osmolity, drawing fluid back in the surrounding tissues > inhibiting resoprtion of H20 + solutes for rapid diuresis in entire nephron, decending loop of henle (proximal end).
  • SE: convulsions, pulmonary congestion
17
Q

spironolactone* (Aldactone)

A
  • Potassium-sparing Diuretics r/t hypertenion, hyperaldosteronism, reversing K+ loss from K+ wasting diuretics, prevents cardiac remodling
  • Promotes excretion of Na and H20, retention of K, blocks aldosterone in distal convoluted tubules.
  • Interactions to avoid comb: lithium, ACE inhibitors, K+ supplements, NSAIDs (decrease response)
  • Contra: severe renal failure, no urine output + known allergy
  • SE: hyperkalemia
18
Q

Nitrates/Nitrites: nitroglycerin (Nitro-Bid, Nitro-Dur) *

A
  • TD (patch works through day to prevent IM attack), SL (systemic for spray under tongue), IV
  • r/t prophylaxis + Tx angina attack
  • vasodilation, decreases preload + myocardial oxygen demand working well on coronary arteries.
  • Monitor BP prior to administration, wear gloves when handling (absorbs easily)
  • SE: HA, hypotension
  • Teach: tx of angina after onset, protect + keep in cool area in dark color bottle, SL take 1 tab at onset of pain (repeat x3 q 5 min, still have CP: go to ER calling 911), check expiration to replace frequently.
19
Q

digoxin (Lanoxin)

A
  • Anti-Dysrythmics r/t abnormal HR/rhythm
  • Increases myocardial contractility (postive inotropic effect) + decreased HR (negative chronotropic effect) prolonging refractory period (longer time for cells to excite)
  • Take AP before dose (teach pt), hold if <60 bpm + call provider if >120, pt wear medic-alert bracelet/necklace
  • SE: toxicity - yellowish visual changes, changes in LOC, n/v, confusion arrythmias (tachy/brady),hypokalemic
  • Tx: hold meds, treat hypokalemia, monitor, ECG
  • Antidote - digoxin immune fab (Digibind)
20
Q

atorvastatin (lipitor)

A
  • Antilipemics r/t hyperlipidemia, hypercholesterolemia
  • Inhibits mobilization in fat enzymes, decreasing prodiciotn of LDL, increasing produciton of HDL
  • SE: hepatotoxicity, GI upset, muscle pain, rhabdomyolysis
21
Q

enoxaparin* (Lovenox)

A
  • 1-2 x D w/ longer half-life
  • Heparin, Anticoagulant r/t atrial fibrillation, MI prevention, prevent DVT
  • inhibit clotting factors, preventing new + growing clots, while doesn’t break down current ones.
  • Monitor many drug interactions, bleeding (bruising, hematuria, in stool, teeth bleeds), BP changes (internal bleeds), LOC, therapeutic range of low platelet count ^ risk of bleeding.
  • May use reverse agent/blood transfusion, given only SQ/IV always in abdomen + check dose w/ another nurse as high risk med (commonly 5k/unit)
  • Short half-life, leaving system very quickly so leave constant IV, usually given q8h SQ
  • Reversing agen is promatine sulfate, bridge clients to warfarin therapty)
  • PT wear medic bracelet, avoid (sharp/hard objects)
22
Q

warfarin (Coumadin)

A
  • Anticoagulent r/t prevent MI + Tx thromboembolic disorders
  • inhibits vitamin K (produced in colon) dependent clotting factor.
  • SE: bleeding
  • Monitor PT/INR (prothrombin time (seconds for blood to clot), international normalized ratio (normal clotting time 2.0-3.5)), purposeful ^ INR for delayed clotting time 1-1. PO
23
Q

clopidogrel (Plavix)

A
  • Antiplatelet r/t prevent MI (Heart attack) + CVA (stroke) more than aspirin (ASA) though much cheaper
  • inhibits platelet aggregation, doesn’t affect number of platelets as it just makes them not stick together as it deactivates the protein for the life of the platelet (7-10 days for platelet death and affect to leave the body).
24
Q

alteplase (activase)

A
  • Thrombolytic drugs r/t MI, Stroke provided in 6 hrs
  • helps dissolve already formed clots, activate the fibrinolytic system (clot lysed quickly)
  • Contra: bleeding states (already on anti-coagulents, recent trauma w/ internal bleed, recent CPR (puncturs/trauma unknown))
  • Short half-life, given w/ heparin to prevent re-occulusion, only IV - central lines and usually high risk drug only given in emergencies.