Exam 2 COPY Flashcards

1
Q

A

A

Dorsal Root Ganglion

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2
Q

B

A

Quadriceps

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3
Q

C

A

Hamstring

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4
Q

D

A

Sensory

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5
Q

Identify the types of neurons involved in the leg withdraw reflex

A

Motor Neuron
Excitatory Interneuron
Inhibitory Interneuron

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6
Q

A (Sudden Spike in Blood Pressure)

A

Nucleus Tractus Solitarius (NTS)

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7
Q

B (Sudden Spike in Blood Pressure)

A

Carotid Sinus

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8
Q

C (Sudden Spike in Blood Pressure)

A

Aortic Arch

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9
Q

D (Sudden Spike in Blood Pressure)

A

Parasympathetic Ganglion

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10
Q

E (Sudden Spike in Blood Pressure)

A

X (Roman Numeral 10)

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11
Q

F (Sudden Spike in Blood Pressure)

A

IX (Roman Numeral 9)

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12
Q

A (Sudden Drop in Blood Pressure)

A

Nucleus Tractus Solitarius (NTS)

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13
Q

B (Sudden Drop in Blood Pressure)

A

IML

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14
Q

C (Sudden Drop on Blood Pressure)

A

Sympathetic Ganglion

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15
Q

D (Sudden Drop in Blood Pressure)

A

Carotid Sinus

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16
Q

E (Sudden Drop in Blood Pressure)

A

Aortic Arch

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17
Q

F (Sudden Drop in Blood Pressure)

A

X (Roman Numeral 10)

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18
Q

G (Sudden Drop in Blood Pressure)

A

IX (Roman Numeral 9)

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19
Q

A

A

Myosin Head

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20
Q

B

A

Myosin

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21
Q

C

A

Tropomyosin

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22
Q

D

A

Actin

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23
Q

E

A

Troponin

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24
Q

F

A

Sarcoplasmic Reticulum

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25
A
Ca Ion
26
B
Myosin Head
27
C
Myosin
28
D
Actin
29
E
Calmodulin
30
F
MLCK
31
G
Sarcoplasmic Reticulum
32
A
DCC Receptor
33
B
Commissural Axion
34
C
Netrin
35
D
Floor Plate
36
E
Slit
37
F
Robo Receptor
38
When the membrane receptor (a) _____________ on the (b) __________________ axon is stimulated by the guidance molecule (c) _____________, it promotes axon progression towards the midline.
a) DCC b) Commissural c) Netrin
39
Therefore, the axon is attracted to the (c) molecule that is secreted by (d) __________________ cells, setting up a concentration gradient.
Floor Plate
40
The cells from (d) also secrete a secondary molecule called (e) ____________, which can repulse axons
Slit
41
When the (b) axons get to (d), they start expressing the membrane receptor (f) ______________, that is activated by molecule (e).
Robo
42
When actively expressed (f) receptors have two effects: 5a. (f) receptors represses the (a) _____________ receptors, making the growth cone less sensitive to (c) _____________. 5b. (f) receptors make the growth cone repulsed by (e) _____________, Collectively causing the axon to cross the midline and ascend on the other side of the spinal cord.
a) DCC c) Netrin e) slit
43
RESULT: As a result of all these molecular interactions, the axons are first ______________ to the floor plate (______________ chemotaxis), and then ______________ by it (______________ chemotaxis).
1) attracted 2) positive 3) repelled 4) negative
44
An action potential propagates across the _____________ and down the ____________, which triggers the release of the ion _______ into the sarcoplasm through special calcium channels on the _____________.
1) Sarcolemma 2) T-tubules 3) Sarcoplasmic Reticulum
45
At high ________ levels, Ca2+ binds to ___________.
1) Ca ion 2) Troponin
46
____________ is physically moved aside and the binding site becomes exposed
Tropomyosin
47
The ____________ attach to the binding site, forming a ____________.
1) Myosin Head 2) Cross Bridge
48
In the presence of __________, the myosin head pulls the actin filament.
ATP
49
END RESULT: The _____________ is shortened and the skeletal muscle contracts.
Sarcomere
50
Following an action potential, ______ enters through voltage-gated ______ channels, which (1b) eventually leads to release of internal Ca2+ stores from the _______________ reticulum
1) Ca Ion 2) Ca Ion 3) Sarcoplasmic
51
When Ca2+ levels rise, Ca2+ binds to __________, creating a ________/__________ complex
1) calmodulin 2) Ca Ion 3) calmodulin
52
This complex activates an enzyme __________
MLCK
53
that phosphorylates the __________. This process of _________________ makes the myosin heads more likely to bind to adjacent ________ filaments
1) myosin head 2) phosphorylation 3) actin
54
_____________ sense increased blood pressure, causing them to trigger action potentials at a _________ than normal rate
1) Baroreceptors 2) Higher
55
Information is transmitted from the baroreceptors in the ___________ (via cranial nerve: ___________) and the aortic arch (via cranial nerve: ___________ ) to a region of the dorsal medulla called the ____________________
1) Carotid Sinus 2) Glossopharyngeal n IX 3) NTS
56
When blood pressure is too high, NTS activates the ________________ system (and inhibits the ______________).
1) Parasympathetic 2) Sympathetic
57
Parasympathetic _______________ neurons synapse with postganglionic neurons (in the parasympathetic __________). Postganglionic neurons project to the _____________, and release the neurotransmitter _______________.
1) preganglionic 2) ganglion 3) SA node 4) Acetylcholine
58
END RESULT : a(n) ____________ in heart rate.
decrease
59
_____________ sense decreased blood pressure, causing them to trigger action potentials at a _________ than normal rate.
1) Baroreceptors 2) lower
60
Information is transmitted from the baroreceptors in the ___________ (via cranial nerve: ___________) and the aortic arch (via cranial nerve: ___________ ) to a region of the dorsal medulla called the ___________________.
1) carotid sinus 2) n IX 3) n X 4) NTS
61
When blood pressure is too low, NTS activates the ________________ system (and inhibits the ______________).
1) Sympathetic 2) parasympathetic
62
A signal is sent from the NTS to the _____________ in the spinal cord.
IML
63
Sympathetic _______________ neurons synapse with postganglionic neurons (in the sympathetic __________). Postganglionic neurons project to the _________________, and release the neurotransmitter _______________.
1) pre-ganglionic 2) ganglion 3) SA node 4) nor-epinephrine
64
After a drop in blood pressure, NTS will also activate the ______________ pathway to the blood vessels.
Sympathetic
65
Postganglionic neurons release the neurotransmitter _________________, which here promotes vasoconstriction of the blood vessels, which results in an ____________ in blood pressure.
1) nor-epinephrine 2) increase
66
END RESULT : a(n) ____________ in heart rate.
increase
67
You just stepped on a tack - OUCH! A signal about this activates mechanoreceptive axons (of ___________) that innervate the foot, which project to the deep layers of the spinal cord’s dorsal horn via the ___________________ (a).
1) Nociceptors 2) Dorsal root ganglion
68
There, the sensory axons synapse on excitatory _______________ (e) that then project to _______________ (f) neurons in the ventral horn.
1) Interneuron 2) Motor
69
These neurons in the ventral horn that received an excitatory signal innervate the _______________ (c) muscles, which flex your leg and pull your foot away from the pain source
hamstring
70
The incoming sensory axon branches and also synapses on inhibitory _______________ (d) that project to additional _______________ (f) neurons in the ventral horn.
1) Interneurons 2) Motor
71
These neurons that received an inhibitory signal innervate the _____________(b) muscles, inhibiting contraction of the leg extensors
quadracep
72
END RESULT : Strong stimulation of the foot triggers ____________ of the leg flexors and ____________ of the leg extensors.
1) Excitatory Interneurons 2) Inhibitory Interneurons
73
Name the two regions of the brain where adult neurogenesis has been documented in mammals
Olfactory bulb and Hippocampus
74
Using the diagram below, label the major layers beneath the scalp in place to protect the brain from injury, including the specific meningeal layers.
1. Periosteum 2. Skull 3. Dura Mater 4. Arachnoid barrier (which also includes the subarachnoid space) 5. Pia Mater
75
A protein that regulates the migration of young cortical neurons along the radial processes of radial cells and signals them to disembark
Reelin
76
Experimentally interfering with signaling (ie, very low levels of this molecule) prevents medulla + spinal cord from forming
Retinoic acid
77
At high levels of expression of this protein, cells leave the cell cycle and begin neurogenesis
Delta-1
78
In a developing spinal cord, this protein causes cells to adopt a more ventral cell fate
Sonic Hedgehog (SHH)
79
If you artificially increase levels of this protein, you would end up with an abnormally large brain
B-catenin
80
The myofibrils of skeletal muscles are striped because they contain a highly regular arrangement of molecules: thin (a) ________ filaments and thick (b) ________ filaments, that repeat every 2-3μm. Each repeating unit is called a (c) ____________
a) actin b) myosin c) sarcomere
81
Pupillary constriction is modulated by which division of the autonomic nervous system?
Parasympathetic division
82
I’m a small star-shaped glial cell that multiplies in response to brain injury, migrates to the site of injury, secretes inflammatory molecules, and engulfs cellular debris
Microglia
83
I am primarily responsible for setting our circadian and seasonal rhythms. I receive projections from retinal ganglion cells that express melanopsin and have an inhibitory connection with the paraventricular nucleus of the hypothalamus
Suprachiasmatic nucleus
84
I graduated from medical school in Italy when Mussolini published his "Manifesto per la Difesa della Razza", which banned of all non-Aryans from having academic careers. So, I set up a secret lab in my bedroom. I found that if I removed the leg from an embryonic chicken and replaced it with a sarcoma, the sarcoma actually rescued many limb motor neurons from death. This was the first evidence of a trophic factor.
Rita Levi-Montalcini
85
I form from aggregates of misfolded Aβ proteins that form in the spaces between nerve cells and am prevalent in the brain of Alzheimer’s disease patients.
Amyloid plaques
86
I’m a type of non-striated muscle that is spindle-shaped. I’m found in the walls of internal organs and blood vessels and am associated with involuntary movement.
Smooth muscle
87
I am found in the medulla and my axon is known as a climbing fiber, which wraps around the Purkinje cell dendrites. I convey error signals to the cerebellum to facilitate motor learning
Inferior Olive
88
Place the following events of neural development in order following fertilization, with 1 being the first event in the process. chordin and BMP direct formation of neural tissue and skin tissue formation of neural plate formation of neural tube blastocyst formation of neural groove
2 chordin and BMP direct formation of neural tissue and skin tissue 3 formation of neural plate 5 formation of neural tube 1 blastocyst 4 formation of neural groove
89
Sympathetic preganglionic neurons are in a column between the dorsal and ventral horns, called the ____________
Intermediolateral column (IML)
90
They exit the spinal cord through the ventral roots of the spinal nerve and terminate in the (a) ____________. There, they release the neurotransmitter (b) ____________
2a. sympathetic ganglion 2b. acetylcholine
91
This neurotransmitter is released onto the dendrites of the ________________
postganglionic neurons
92
These neurons then innervate the smooth muscle surrounding blood vessels and release the neurotransmitter ________________.
norepinephrine
93
Describe the major steps in the process of chemical transmission at the neuromuscular junction. Be sure to include the different voltage & ligand gated channels, correct neurotransmitter, & the ions involved!
Step 1: Action potential arrives at axon terminal Step 2: Voltage gated Ca2+ channels open and Ca2+ enters the axon terminal Step 3: Ca2+ entry causes synaptic vesicles to move to the presynaptic membrane and release acetylcholine via exocytosis Step 4: Acetylcholine diffuses across the synaptic cleft and binds to the ligand-gated ion channels on the post-synaptic membrane Step 5: Binding of ACh opens channels, resulting in Na+ entry and depolarization (EPP) Step 6: Action potential then propagates along Sarcolemma Step 7: Reduction of neurotransmitter levels, terminating the signal (via reuptake by the presynaptic neuron, enzymatic degradation (acetylcholinesterase) and diffusion)
94
Name TWO WAYS in which chemical transmission at the neuromuscular junction differs from a normal chemical synapse.
DIFFERENCE 1`: At the normal adult neuromuscular junction, the ion influx almost always triggers a postynaptic action potential. It is very reliable, unlike other synapses. DIFFERENCE 2: is that we call this depolarization the End Plate Potential (EPP). EPP NOT an action potential, but can depolarize the membrane of the postsynaptic cell and initiate an action potential. The end-plate potential looks and behaves much like EPSPs in nerve cells and is sufficient to trigger an action potential and subsequent contraction of the muscle
95
Put the following events in order following an action potential, resulting in contraction of smooth muscle by writing numbers 1-7 on the line:
4 The myosin heads are phosphorylated 1 Ca2+ enters through voltage-gated Ca2+ channels and is released from internal stores from sarcoplasmic reticulum 5 Myosin heads are now more likely to bind to adjacent actin filaments 2 Ca2+ binds to calmodulin, creating a Ca2+/calmodulin complex 3 The enzyme MLCK is activated 6 The muscle contracts
96
Consider the leg withdrawal reflex after stepping on a sharp object with your left foot. In this reflex circuit, name the muscle that is excited (contracted) and the one that is inhibited (relaxed) in the same leg?
The leg withdrawal reflex contracts the leg flexors (hamstring) and inhibits the leg extensors (quads)
97
Imagine you have a sudden spike in blood pressure. Answer the following question by circling or highlighting the correct options related to regulation of heart rate when your blood pressure gets too high
Baroreceptors sense increased blood pressure 2. Causing them to trigger action potentials at a higher than normal rate 3. This Information is transmitted from the carotid sinus via the glossopharyngeal (nIX) nerve and the aortic arch via the vagus (nX) 4. To the nucleus tractus solitarius (NTS) 5. This structure then activates the parasympathetic system and inhibits the (circle one) sympathetic 6. Postganglionic neurons project to the SA Node 7. And release acetylcholine 8. This results in a decrease in heart rate
98
Define what is meant by “Excitotoxicity” and explain how astrocytes help to minimize this.
Excitotoxicity: Excessive stimulation of neurons (e.g. by glutamate) that leads to excessive neural firing and, in some cases, cell death. Some types of astrocytes possess potassium channels that allows K+ to flow INTO the cell rather than out of it, which allows astrocytes to take up excess potassium (e.g. potassium buffering). This keeps K+ concentrations lower in extracellular space, which allows K+ will flow out of a recently depolarized neuron (e.g. repolarization). This process helps to get the cell get back to its resting membrane potential. Thus, by taking up excess K, astrocytes help prevent a neuron dying of excitotoxicity
99
How would you explain the difference between “red meat” and “white meat” to someone who has never taken a biology class before? Name two key characteristics that we can associate with dark vs. light meat. Answers can include characteristics related to twitch speed, speed/strength of contraction, and where they derive their energy
Muscle fibers vary in their myoglobin content. Because myoglobin is red, you can visibly see muscle that has a lot of myoglobin. Can have stated any two of the following: “Dark Meat” - muscles that contain a high density of myoglobin * Primarily slow twitch fibers * More myoglobin means wean ferry more oxygen to the muscle, so this muscle type can stay contracted for longer (ie, fatigue resistance) * Slow contractions, more force * Large, strong muscles (e.g. leg muscles) * derives most of its ATP from oxidative phosphorylation “White Meat” – muscle that contains little myoglobin * Primarily fast twitch fibers * Fast contractions, less force * Less oxygen means they can't stay contracted as long * Small muscles (e.g. eye muscles, vocal cords) * Derives most of its ATP from glycolysis
100
Name the three germ layers of a developing gastrula. Of these three, which is fated to become nervous system?
Ectoderm, Mesoderm, Endoderm - The ectoderm develops mainly into the epidermis (skin) and nervous system.
101
If I were to add semaphorin to the upper right corner of a petri dish (at the star in the figure below), creating a concentration gradient, describe the way that a developing axon might grow after 60 minutes
Semaphorin is a protein that tends to repel growing axons by causing the filopodia of their growth cones to collapse. Therefore, after 60 minutes, the axon would grow down the concentration gradient (negative chemotaxis) towards the bottom left corner.
102
Describe the pathway from nuclei in the hypothalamus, resulting in the release of vasopressin into the bloodstream (be specific about neuron types, hypothalamic nuclei, hormone storage, and location of capillary bed). Name two ways in which this differs from the pathway from the hypothalamus to the anterior pituitary
1. Magnocellular hypothalamic neurons in the supraoptic and paraventricular nuclei synthesize vasopressin 2. Hormones are packaged into vesicles & transported down the magnocellular axons to the posterior pituitary 3. Vasopressin is stored in the axon terminals in the posterior pituitary 4. When associated hypothalamic neurons fire, action potentials arriving at the axon terminals cause vasopressin to be released into the blood into the capillary bed in the posterior pituitary Differences (could be any two of the following) * Parvocellular neurons in the paraventricular and supraoptic nuclei * Anterior pituitary uses releasing hormones o Releasing hormones: synthesized in parvocellular neurons, released into upper capillary bed o Pituitary hormones: synthesized in pituitary cells in anterior pituitary; released into lower capillary bed * 2 capillary beds: one in upper and lower anterior pituitary * Pituitary Hormones released: GH, ACTH, LH, FSH, or TSH
103
The axons of a commissural neuron in the spinal cord grow ventrally at first because they are attracted to (a) _____________, but then cross over to the other side of the floor plate and start to ascend the other side because they are repulsed by (b) ___________.
(a) netrin (b) slit
104
Name the structure to the left of this neuron’s cell body
It is a neuron’s growth cone (ie the tip of a growing axon), regularly extending and retracting slender protrusions called filopodia. Either growth cone or filopodia would have been an acceptable answer here.
105
What do you call an afferent neuron (free nerve ending) preferentially sensitive to noxious stimuli?
Nociceptor
106
Purkinje Cells Receives Input From
1. Granule cells 2. Inferior olive/climbing fibers
107
Granule Cells Receives Input From
Precerebellar nuclei
108
Purkinje Cells Sends info to / Target(s)
1. Vestibular complex 2. Deep cerebellar nuclei
109
Granule Cells Sends info to / Target(s)
Purkinje cells
110
The brain is protected from blood-borne threats by three major barriers, each formed by tight junctions between specific types of cells. Name the barriers and the cell types for each.
(1) Blood brain Barrier: barrier to the flow of large hydrophilic molecules from the blood into the brain. Formed by tight junctions between endothelial cells. (2) Blood-CSF Barrier: barrier to the flow of large hydrophilic molecules from the blood into the cerebrospinal fluid. Formed by tight junctions between epithelial cells. (3) Arachnoid Barrier: A very thin layer of cells between the subarachnoid space and the veins or sinuses, formed by tight junctions between its arachnoid cells
111
Of the three muscle types we discussed, which one contracts the slowest?
Smooth muscle (contracts 300-500 times slower than skeletal muscle)
112
Name two parts of the body that are dramatically over-represented in the motor cortex, as reflected in Penfield’s motor homunculus.
There are a few different acceptable options here. You could have said any of the following: * Hands * Fingers * Face * Tongue
113
Which of the following contains baroreceptors that are responsible for detecting blood pressure changes in the blood vessels? a. Nucleus Tractus Solitarius (NTS) b. Carotid Sinus c. SA node d. IML
Answer: B carotid sinus
114
The Vestibulo-ocular reflex helps minimize _________________ .
Retinal Image Slipping
115
If retinoic acid (RA) is artificially increased, what would most likely be the outcome for the embryo? A: The embryo would most likely develop with no forebrain. B: The embryonic brain region's fate will become more caudal. C: Both A and B D: None of the above
C. Both A and B
116
There are three major axes that pass through the anterior pituitary gland. Which major axis matches correctly with its purpose? a. Hypothalamic pituitary adrenal, reproduction b. Hypothalamic pituitary gonadal, metabolism c. Hypothalamic pituitary thyroid, stress d. Hypothalamic pituitary adrenal, stress
d
117
In your neurobiology class, you learned about different muscle fibers and their roles in the human body. What would happen if you, for some reason, decided to switch the type of muscles in your eyes with their "opposite"?
A and D
118
Which of the following is true about smoth muscle A) they are organized in sarcomeres B) they have intercalated discs C) they control actin-myosin binding by calcium-calmodulin-activated phosphorylation of the myosin heads D) they can't fire action potentials
c
119
What is the main function of having a leaky section on the blood brain barrier ?
Allows lymphocytes in, incase of an attack
120
What is the section of the brain found within the hypothalamus that is responsible for setting pituitary hormone levels and for setting the circadian rhythm?
Suprachiasmatic nucleus
121
Which binds netrin? a)BMP b) ROBO receptor c)SLIT d) DCC receptor
The answer is DCC
122
What is the “default” cell fate of ectodermal tissue in early embryonic development?
Rostral Nervous System Tissue
123
Which of the following is NOT true of the parasympathetic nervous system? A. Connects all up and down the spinal cord B. Increases intestinal and gland activity C. Has very little branching D. Conserves energy
A. Connects all up and down the spinal cord
124
In the process of neurulation which forms first?
neural plate
125
Cerebrospinal fluid (CSF) is primarily secreted by
choroid plexus cells
126
When ___ is released the heart rate is going to increase, and when ____ is released heart rate is going to slow down.
norepinephrine, acetylcholine
127
Which type of muscle below BEST fits this description? This muscle is striated, cylindrical in shape, bundled into fascicles, there are multiple nuclei per muscle fiber, and they are striated. A. Smooth Muscle B. Cardiac Muscle C. Skeletal Muscle D. None of the above
C
128
Which of the following accurately describes the adrenergic receptors? A) Adrenergic receptors are G-proteins that bind to epinephrine. Alpha-adrenergic constricts the smooth muscle cells surrounding blood vessels causing the Blood pressure to Increase. B) Adrenergic receptors are metabotropic receptors that bind to norepinephrine. Beta-adrenergic causes the relaxation of the smooth muscle cells surrounding blood vessels causing a decrease in blood pressure C)Adrenegeric receptors are G-proteins that bind to epinephrine. Alpha-adrenergic relaxes the smooth muscle cells surrounding the blood vessels causing a decrease in blood pressure D) Adrenegeric receptors are metabotropic receptors that bind to norepinephrine. Beta-adrenergic causes the smooth muscle cells surrounding the blood vessels to constrict which causes an increase in blood pressure.
Adrenergic receptors are metabotropic receptors that bind to norepinephrine. Beta-adrenergic causes the relaxation of the smooth muscle cells surrounding blood vessels, causing a decrease in blood pressure.
129
What would be the effect of no sonic hedgehog being released during embryonic development?
Development of sensory neurons
130
What is the fate of the neural crest?
Some parts of the peripheral Nervous system
131
Which of these repels growing axons by causing filopodia of the growth cones to collapse? A) Netrin B) Semaphorin C) DCC D) Slit
Semaphorin
132
What type of synapse occurs between a motor neuron and a skeletal muscle fiber and what type of synapse is it?
neuromuscular junction and chemical synapse
133
Which of the following is TRUE of the types of specialized glial cells? a. Microglia are the smallest glial cells in the Central Nervous System. Microglia help protect the brain by removing debris and helping control damage to the brain. b. Astroglia are medium-sized glial cells in the Peripheral Nervous System. Astroglia’s function is to form myelin around the axons of neurons in the brain. c. Oligodendrocytes are glial cells present in the Peripheral Nervous system. They are asymmetrical and their function is to help provide nutrition and support to the neuronal cells. d. Schwann cells are star-shaped cells in charge of the removal of waste and toxins from the Central Nervous System.
Microglia are the smallest glial cells in the Central Nervous System. Microglia help protect the brain by removing debris and helping control damage to the brain.
134
_____ is the tissue of the brain (excluding ependymal cells and blood vessels).
parenchyma
135
An increase in retinoic acid concentrations in an a human embryo primarily stunts growth in what CNS region?
Forebrain
136
After receiving a noxious stimulus, during a leg withdrawal reflex, what neuron(s) in the spinal cord is the signal NOT passed through?
Sensory Neuron
137
Which neurotransmitter is responsible for the increase in heart rate in response to low blood pressure?
Norepinephrine
138
What is the thin membrane of glial cells lining the ventricles of the brain and the central canal?
Ependyma
139
The parasympathetic nervous system controls what?
Pupillary constriction
140
In response to stress, your pituitary hormone releases adrenocorticotropic-stimulating hormone (ACTH). Activation of what axis causes this release of ACTH?
HPA
141
Which of the following is a task of the Hypothalamic-Pituitary-thyroid (HPT)?
Regulates metabolism
142
How many segments is our spinal cord and brain subdivided into?
31:3
143
Which muscle type lines the walls of the intestines, bladder, blood vessels, and bronchial passageways?
Smooth muscle
144
If the Bone Morphogenic Protein (BMP) approaches the _______, it will be _______ by chordin and turn the Ectoderm into the Future nervous system.
Dorsal Blastopore Lip, Inactivated
145
Which pituitary hormone(s) are released from the Hypothalamic-Pituitary Gonadal (HPG)?
Luteinizing hormone (LH) and Follicle-Stimulation hormone (FSH)
146
When information is sent from the baroreceptors by cranial nerve: _____ and cranial nerve: ______ to the region of NTS. What are the two cranial nerves?
nX, nIX
147
Which is FALSE regarding Alzheimer's disease? A. Neurofibrillary tangles form from misfolded Tau proteins B. Misfolded Aβ proteins aggregate C. Decreased expression of cytokines, chemokines and microglia around amyloid plaques D. Neurons with plaques commit apoptosis
C. Decreased expression of cytokines, chemokines and microglia around amyloid plaques
148
What type of cell can turn into neural tissue?
Ectoderm
149
Refer to the provided image about the Arachnoid Barrier and its functions. Based on the details of the arachnoid Barrier: This diagram shows the Arachnoid Barrier's relation to CSF flow, including arterial blood movement through endothelial cells and tight junctions. It also depicts the collection of CSF from the ventricles and its transport through arachnoid cells into venous blood. Which of the following statements is FALSE about the CSF and the arachnoid barrier? A) CSF is primarily collected from the ventricles and then gathers in the Subarachnoid space. B) The arachnoid barrier is composed of a dense layer of cells separating the ventricles from the subarachnoid space. C) Within the arachnoid barrier, the CSF is transported to veins using giant vacuoles which float through the arachnoid cells and then release their contents. D) Tight junctions primarily exist between the cells of the blood-brain barrier and not in the arachnoid barrier.
B) The arachnoid barrier is composed of a dense layer of cells separating the ventricles from the subarachnoid space.
150
What are the four pituitary gland hormones?
1.) Adrenocorticotropic (ACTH) stimulating hormone 2.) Luteinizing hormone (LH) 3.) Follicle stimulating hormone (FSH) 4.) Thyroid stimulating hormone (TSH)
151
What is the Blood CSF Barrier formed by?
A. Tight junctions between epithelial cells in the choroid plexus
152
What hormone is secreted by the anterior pituitary gland?
Growth hormone
153
What does the Circle of Willis in the brain do to help with cerebral blood flow?
links major arteries feeding the brain and minimizes potential brain damage
154
What lies in the paired cerebral hemispheres?
Lateral ventricles
155
In dorsoventral patterning, neurons that ____ their axons to muscles lie ______ and neurons that _____ input from sensory nerves are located______.
Send, Ventrally; receive, dorsally
156
What part of the motor cortex has relatively direct projections to motor neurons in the medulla and spinal cord?
Primary motor cortex
157
Which glia is present in the PNS?
Schwann cells
158
what molecule obstructs the myosin binding site on an actin filament when a muscle is relaxed.
Tropomyosin
159
What is not true about reflexes?
They are immutable
160
What type of gland secretes its contents (hormones) into the blood?
Endocrine
161
A (alpha) Fibers
Carry information from proprioceptive receptors in muscles and tendons
162
A (bravo) Fiber
Carry information from the mechanoreceptors in the skin on pressure and vibration
163
A (delta) Fibers
Carry information about pain and temperature
164
C Fibers
Carry information about pain, temperature, and itch
165
A (alpha) Fibers
* Thickest axons (13-20 μm) * Myelinated
166
A (bravo) Fibers
* Thick axons (6-12 μm) * Myelinated
167
A (delta) Fibers
* Thin axons (1-5 μm) * Myelinated
168
C Fibers
* Thinnest axons (0.2-1.5 μm) * Unmyelinated axons
169
Both diameter and myelination critically increase __________ of action potential propagation
speed
170
_________ (thickest, myelinated) Conduction speed: 80-120 m/s
A (alpha) Fibers
171
_________(thick, myelinated) Conduction speed: 35-75 m/s
A (bravo) Fibers
172
_________ (thin, myelinated) Conduction speed: 5-30 m/s
A (delta) Fibers
173
_________ (thinnest, unmyelinated) Conduction speed: 0.5-2 m/s
C Fibers
174
Spinal Cord
a long, thin tubular structure that comprises part of the central nervous system
175
Spinal Nerve
a mixed nerve, which carries motor, sensory, and autonomic signals between the spinal cord and the body
176
Doral Root
A bundle of axons that enters a segment of the spinal cord dorsally and consists mainly of sensory axons
177
Ventral Root
A bundle of axons that exits a segment of the spinal cord ventrally and consists mainly of motor axons
178
Dorsal root ganglion
A small swelling in each dorsal root that contains the cell bodies of sensory neurons (afferent)
179
Cell bodies in the dorsal root ganglia do not have dendrites and give rise to just ________
one axon
180
pseudounipolar
Neuron with a single process emerging from the cell body, which splits into two major branches
181
99.8% of the cell’s cytoplasm is in the _______
axon
182
Dorsal horn
a region at the back of the spinal column that receives input from mechanoreceptors in the skin
183
_______________ fiber tract ascends to the caudal medulla and terminates in the Dorsal column nuclei (DCN)
Dorsal column
184
One branch terminates in the ___________ of the grey matter, close to where the fibers enters the spinal cord
dorsal horn
185
Trigeminal nerve
The fifth cranial nerve (nV) that contains somatosensory axons coming from the face
186
Aβ fibers in the trigeminal nerve project to the _________________ of the trigeminal nerve, which is located in the caudal pons (hindbrain)
principle nucleus
187
Somatotopic Organization
Organized in such a way that adjacent parts of the body (usually the skin) are represented at adjacent locations in the brain
188
Ascending projections are ______________ organized
Topographically
189
Primary somatosensory cortex (S1)
A thin strip of cortex that receives input from the dorsal thalamus
190
Homunculus
a drawing of a “little man” that is a map-like representation of regions of the body in the brain
191
Somatosensory homunculus
A drawing of a “little man”, showing the degree to which a part of the body is over- or underrepresented in the somatosensory cortex
192
The overrepresented regions (e.g. _______& _________) are areas of high touch acuity
hands; face
193
Barrel Cortex
A part of the rodent’s primary somatosensory cortex (S1) that represents the whiskers
194
Exact ____________ of position of whiskers
replica
195
Lateral inhibition
The process by which neighboring neurons inhibit each other
196
Contact between an object and our skin activates S1 in a ___________ pattern that reflects the objects shape
spatial
197
Neuronal rewiring is very common after brain injury and tends to help restore __________________
behavioral function
198
The degree to which the occipital cortex responds to somatosensory stimuli depends on the ________________ at which the person became blind
age
199
Loss of input from the hand causes extensive “______________” in somatosensory cortex
Remapping
200
Phantom Limb
A pain felt in the region of the body that is no longer there (eg, due to amputation) or is no longer innervated by sensory axons (eg, due to spinal cord injury)
201
Somatosensory inputs from the face are ____________ to the cortical region used to process info from the arm or leg lost
rerouted
202
Thermoreceptor
a sensory receptor that signals information about changes in skin temperature
203
cold fibers
a sensory nerve fiber that fires when skin temp decreases
204
warmth fibers
a sensory nerve fiber that fires when skin temp increases
205
Actual temperature is encoded by comparing __________________ of warmth and cold receptors and that of nociceptors.
relative contribution
206
Thermally-sensitive transient receptor potential (ThermoTRP) channels
temperature-sensitive ion channels found in sensory neurons
207
TRP channels are activated over a specific _________ of temperatures
range
208
Thermoreceptors fire when we make contact with an object that is ____________________ than our skin
warmer or colder
209
Nociception
The neural process of encoding and processing noxious stimuli
210
Noxious stimuli
Damages or threatens to damage tissue (mechanical, thermal, or chemical)
211
Nociceptor
Afferent neuron preferentially sensitive to noxious stimuli
212
Nociceptors have ___________________ that respond to various types of tissue damage or to stimuli that has the potential to damage tissue
five nerve endings
213
Thermoreceptive and nociceptive axons enter at the __________ of the spinal cord
dorsal horn
214
Substantia gelatinosa
a dorsal region of the dorsal horn of the spinal cord, where nociceptive axons terminate
215
Spinothalamic tract
route from the spinal cord to the brain that carries information about skin temperature & nociceptive signals *Terminates in dorsal thalamus, midbrain and medulla
216
Conscious perception of painful stimuli occurs in the ______________ Cortex
somatosensory
217
Axons of the spinothalamic tract will synapse with relay nuclei in the hindbrain and midbrain and converge in the ______________ nucleus of the dorsal thalamus
ventral posterior
218
Congenital insensitivity to pain (CIP)
a condition that inhibits the ability to feel physical pain
219
Analgesia
decreasing pain sensation during conscious experience
220
Exogenous opioids
chemical compounds related to opium and are NOT produced by the organism’s own body (e.g. morphine, heroin)
221
Endogenous opioids
chemical compounds that are related to opium and are produced by the organism’s own body (eg. endorphin)
222
_________ bind to G-protein coupled opioid receptors
Opiods
223
Neurons that express the activated opioid receptors become much less excitable (______________)
hyperpolarized
224
Opioid receptors are located in many nociceptive axons that terminate in the __________________
substantia gelatinosa
225
If the signal fails to reach the higher levels of the brain, then pain is not _______________
perceived
226
placebo
decreasing pain sensitization when people think they’re taking an analgesic drug, but aren’t
227
Activating touch sensitive axons (AB fibers) excite inhibitory neurons in the spinal cord that _________ the ability of nociceptive axons to transmit signals to higher brain regions
reduce
228
Gate control theory
a description of the pain-transmitting system that incorporates modulating signals from the brain
229
Can deliver weak __________________ to a patch of skin close to the site of the chronic pain
electrical current
230
hypersensitivity
an increased or heightened response to a normally painful stimulus
231
What cranial nerve carries sensory information from the face, sinuses, and teeth?
Trigeminal
232
Responses to continuous stimulations can include both slaw and rapid adaptation. Mechanoreceptors that are slow adapting (SA) fibers include _____ and _____, while rapid adapting (RA) fibers include _____ and _____
Merkel Disks; Ruffini endings; Meissner corpuscles; Pacinian corpuscles
233
What is the term for an individual's inability to process visual information in their left visual world when an object is present in their right visual world?
neglect
234
Which semicircular canal senses the angular motion of nodding your head "yes"?
Anterior semicircular canal
235
The vibration of the _____ activates the haircells
Basilar membrane
236
If a patient experienced damage to their arcuate fasciculus, what problems would they likely experience?
Inability to repear sentences the patient has heard (Conduction aphasia)
237
Your two friends Becky and Sam are arguing over hair cells (as one does). Becky is convinced that hair cells are neurons, but Sam vehemently disagrees, They ask you to settle this once and for all. Who do you side with and why?
You side with Sam because hair cells do not generate action potentials and do not have axons.
238
Describe Ames Room
A room that creates a forced perspective by angling both the ceiling and floor to trick your eye into thinking both sides of the room are the same.
239
If a person is able to see everything except the current object of attention, they may have what condition?
Balint syndrome
240
What causes the release of glutamate in the auditory system.
Due to the pressure wave traveling up and down the scala vestibuli and scala tympani, moving the scala media up and down. This deflection pulls the tip links that open the mechanically gated K+ channels allowing for K+ to rush into the cell depolarizing it and this depolarization opens voltage-gated Ca2+ channels that cause the ribbon synapse to release glutamate.
241
Which receptor would best respond if you where to stretch at the gym?
Ruffini endings
242
Which carries information about pain and temperature
A (delta) Fibers
243
Patients with Broca;s aphasia have the inability or difficulty to _____, whereas in whenicke's aphasia patients have the inability to _____.
produce articulate speech; comprehend speech
244
You and your friend are stuck in standstill traffic on a long road trip. Since you're in the passenger seat you decide to close your eyes and try to get some sleep. However, as soon as you do, the traffic miraculously clears up and you get the sensation of the car accelerating forward. You notice this sensation due to which vestibular component?
Utricular Macula
245
Which of the following is FALSE in regard to the left and right cochlea and their pathways to the lateral superior olive? A. Lateral superior olive neurons are sensitive to interaural level differences. B. The lateral superior olive receives excitatory projections from the ipsilateral cochlear nucleus and inhibitory input from the contralateral cochlear nucleus. C. When the excitation is stronger than the inhibition, neurons in the lateral superior olive will increase in their firing rate. D. When the inhibition is stronger than the excitation, neurons in the lateral superior olive will increase in their firing rate.
D) When the inhibition is stronger than the excitation, neurons in the lateral superior olive will increase in their firing rate.
246
Which of the following descriptions of the type of nerve fibers that transmit somatosensory information to the brain is INCORRECT? A. A-alpha fibers have the thickest axon diameter, are myelinated, and have the fastest conduction speed. They carry information from proprioceptive receptors that innervate muscles and tendons. B. A-beta fibers have thick axon diameters and are myelinated, with a fast conduction speed. They carry information from mechanoreceptors in the skin that sense touch, pressure, and vibration. C. A-delta fibers have thin axon diameters, are unmyelinated, and have a slow conduction speed. They carry information from free nerve endings that can sense pain, temperature, and itch. D. C-fibers have the thinnest diameter, are unmyelinated, and have the slowest conduction speed. This type carries information that can sense pain, temperature, and itch.
C. A-delta fibers have thin axon diameters, are unmyelinated, and have a slow conduction speed. They carry information from free nerve endings that can sense pain, temperature, and itch.
247
The airway above the larynx used for the production of speech is referred to as what...
Vocal tract
248
What nerve fiber is characterized by its lack of myelination and slow condcution speed?
Node C
249
What is the relationship between sound frequency and the location of maximal basilar membrane vibration?
Low frequency is neer the cochlear apex and high frequecny is near the cochlear base
250
Which type of spatial attention involves the superior colliculus
Involuntary spatial attention
251
What is the name of the thin filament connecting the sterocilium together in the inner ear
Tip links
252
What order does sound wave travel via the cochlea
up the scala vestibula, down the scala tympani
253
What is it called when hearing loss occurs due to defects in the cochlea or auditory nerve
Sensorineural hearing loss
254
Which of these structures is part of the inner ear? A. Pinna B. Tympanic membrane C. Oval Window D. Cochlea
D the cochlea
255
Which receptor is located at the epidermis.dermis border, detect light, and are responsive to sustained pressure and touch
Merkel Disks
256
Which of the following sensory functions is primarily associated with Pacinian corpuscles? a) Detecting changes in head position and linear acceleration b) Sensing light touch and texture on the skin's surface c) Monitoring muscle tension and joint position d) Perceiving vibrations and deep pressure in tissues
d) Perceiving vibrations and deep pressure in tissues
257
_______ is sensitive to the acceleration/deceleration of the head forwards, backward, and sideways, whereas _____ is sensitive to the acceleration,/deceleration of the head upwards, downwards, and effects of gravity.
Utricle; saccule
258
What is the correct order of steps of the triggering of a saccade? A: a light flashes in your visual field B: signal goes to the deep layers of the Superior Colliculus C: visual activity is generated in the superficial layers of the Superior Colliculus D. eye saccade towards the light is triggered
ACBD
259
What is the second tinniest but still myelinated sensory fiber
A (delta) Fiber
260
Touch receptors in the mouth and face project information to which area?
Priciple Trigeminal Nucleus
261
Yikes, there are flies buzzing all around! Which mechanoreceptors are going to respond to a fly landing on your arm and then crawling down to your hand?
Merkel Discs and Meissner Corpuscles
262
Meissner Corpuscles, which respond to frequencies between 3-40hz, specialize in what kind of perception?
Pressure
263
What is one part of the ear that could be damaged in sensorineural hearing loss?
Cochlea
264
Becky always knows her mother has arrived home when she feels the vibrations from her car in the driveway. Which type of mechanoreceptor and adaptive response is Becky experiencing?
Pacinian corpuscle with fast, beginning and ending firings
265
Which nerve fiber type is the fastest?
A (alpha) Fiber
266
Which pairing is incorrect? A. Markel disks - Pressure discrimination B. Ruffini endings- Continuous pressure C. Pacinian corpuscles- light pressure sensors D. Meissner corpuscle- deep pressure sensors
C. Pacinian corpuscles- light pressure sensors
267
Which of the following is false about binocular depth cues? A. The horopter is the location of objects whose images lie on corresponding points. B. An object on the horopter with corresponding retinal points has a binocular disparity of zero. C. The shorter the distance in depth of object from the horopter, the larger the binocular disparity. D. Images of objects fall on corresponding points is they are the same distance from the fovea in both eyes.
C. The shorter the distance in depth of object from the horopter, the larger the binocular disparity.
268
Your Brother decided to branch-out with his talents & recently took-up the Drums after hearing TNT by AC/DC as his Baseball Walk-up Song. Although you feel like your Ear Drums are going to burst, you support him hoping he'll be a professional in either one day - to give him a leg-up at his lessons, you explain to him which Cortices are responsible for how he perceives speech & music:
Primary Auditory Cortex (A1) identifies fundamental elements of music like pitch & loudness, Belt Area (A2) is involved in processing Rhythm as well as a difference/anomaly in Melody, & Parabelt Area (A3) is involved in processing Rhythm
269
What information is represented laterally in the DCN?
Arms and Upper trunk
270
our cat gently brushes against your arm, and it gives you a slight tickling sensation. What structure-- found only in not glabrous skin-- is the reason for this phenomenon?
Root hair plexus', which detect the motion of hair cells
271
Which vestibular structure is responsible for sensing vertical acceleration?
saccular macula
272
You sat outside without sunscreen for several hours in direct sunlight. Once you got inside, you notice that you feel a sharp pain and then a tingling/chilling sensation once in the shower when water goes over the skin. You get out of the shower and notice that your shoulders and chest are very bright red and starting to blister. A few days later you till get a throbbing/ tingling sensation if someone toucher the area or if you bump into anything. What is the correct order of events that lead your body to deliver the message that you had injured tissue in responce to the severe sunburn you suffered?
A-delta channels fire, presenting with a sharp pain, letting you know you have sustained an injury. C-fibers fire and deliver the sensation of tingling/throbbing to let you know that you have sustained an injury and will continue to fire until the injury heals. Because your sunburn is so severe, TRP-A1 and TRP-V2 channels fire, causing you to feel chills in the aftermath of the development of the severe sunburn and your shower.
273
How does changing the vocal tract's shape affect speech production?
Alters energy at different frequencies
274
Which perceptions is correlated with Meissner corpuscle receptors?
Pressure
275
Meissner corpuscles perceive...
pressure
276
A-alpha fibers are the ________and so the ________transmitting nerve fiber
thickest, fastest
277
Utricles are sensitive to the head moving __________ (direction), saccules are sensitive to the head moving ________ (direction)
forward/backward/sideways, up/down/gravity
278
Which of the following are true regarding the vestibular system? A: The semicircular canals are located in the inner ear and are used to detect linear motion and tilt. B: The ampulla is the part of the otoliths where transduction of linear motion occurs. C: The otoconia are small stones in the ear which provide inertial mass to sense acceleration. D: There are 3 semicircular canals and 3 otoliths that make up the vestibular labyrinth.
C: The otoconia are small stones in the ear which provide inertial mass to sense acceleration.
279
The 2nd order neuron in the posterior column pathway passes from the:
Medulla to thalamus
280
Which of the following is NOT a monocular depth cue? a. Occlusion b. RelaEve Height c. Convergence d. Texture Gradient e. Aerial PerspecEve
c
281
You are driving, looking ahead. In your peripheral vision, a cyclist suddenly appears. This is _____ aXenEon. a. Overt, voluntary b. Overt, involuntary c. Covert, voluntary d. Covert, involuntary
b
282
Which of the following statements is TRUE concerning the superior colliculus? a. Weak sEmulaEon generates overt shi[s in aXenEon b. Strong sEmulaEon generates covert shi[s in aXenEon c. It is closely linked to involuntary shi[s in visual spaEal aXenEon d. It is involved in compuEng "top down" saliency
c
283
The amplitude of a sound is the: a. amount of sound energy falling on a unit area b. frequency of the sound c. magnitude of displacement of a sound pressure wave d. psychological aspect of sound related to frequency e. pitch
c
284
Which structures are ALL classified as part of the middle ear? a. Pinna, Ear Canal, Tympanic Membrane b. Oval Window, Ossicles, Tympanic Membrane c. Ossicles, Cochlea, Tympanic Membrane d. Ossicles, Ear Canal, Pinna
b
285
If everything except the current object of aXenEon is blocked from conscious percepEon, this would suggest a. Balint Syndrome b. Neglect c. ExEncEon d. Le[ parietal lobe damage
c
286
Which of the following statements is TRUE concerning how sound is transduced? a. The scala media contains perilymph, creaEng an electrical gradient b. Movement of the basilar membrane ulEmately causes hair cells to bend c. Hair cells have voltage-gated K+ channels that open when hair cells deflect d. When the stereocilia are straight Ep links are pulled taught
b
287
Consider the auditory pathway; which structure in the path receives direct informaEon from the superior olives? a. inferior colliculus b. medial geniculate nucleus c. primary auditory cortex d. cochlear nucleus
a
288
Which of the following statements is TRUE when a sound is heard off to your le[? a. The right lateral superior olive is excited by the le[ cochlear nucleus b. The medial superior olive is sensiEve to ILDs, & sends the informaEon on c. ExcitaEon by le[ cochlear nucleus is stronger than inhibiEon from right d. The sound will be loudest to your right ear
a
289
How do we encode sound frequencies? a. The higher the pitch, the more neurotransmiXer that is released b. Sound frequencies are only encoded in the primary auditory cortex c. The lower the frequency, the fewer the # of hair cells are acEvated d. Sound frequencies vibrate at different areas of the basilar membrane
d
290
If someone can produce speech but can't comprehend words, what region of the brain do you predict is impaired? a. Broca's area b. Wernicke's area c. Primary auditory cortex (A1) d. Arcuate fasciculus
b
291
An octave is the a. amplitude of a piece of music b. interval between two sound frequencies having a raEo of 2:1 c. frequency range of a parEcular piece of music d. musical distance between two chords e. absolute frequency difference between two notes in the same interval
b
292
Which five organs make up the vesEbular system? a. One semicircular canal and four otolith organs b. Two semicircular canals and three otolith organs c. Three semicircular canals and two otolith organs d. Two semicircular canals, two otolith organs, and one cochlea
b
293
If you close your eyes and nod your head "yes”, you are experiencing _______, which is registered by your _____. a. angular moEon; otolith organs b. linear moEon; otolith organs c. linear moEon; semicircular canals d. angular moEon; semicircular canals e. Elt; otolith organs
d
294
If, for some unfortunate reason, your utricular maculae was destroyed, what do you predict the impact would be? a. You would struggle to sense gravity b. You would not sense when a car accelerates without visual cues c. Your vesEbulo-ocular reflex would be impaired d. You would not sense when an elevator starts to ascend without visual cues
b
295
The two mechanoreceptors with large recepEve fields (and therefore low touch acuity) are: a. Meissner corpuscles & Pacinian corpuscles b. Pacinian corpuscles & Ruffini endings c. Ruffini endings & Merkel disks d. Merkel disks & Meissner corpuscles
b
296
Which funcEonality would be most affected if you lost your Meissner touch receptors? a. Texture and high-resoluEon paXern percepEon, like for reading Braille b. SensiEvity to stretching the skin to hold an object c. The ability to feel the vibraEons from a car driving by d. The ability to sense cold and warmth of objects touching the skin
a
297
If you stand sEll in one place for awhile without moving, you eventually won't feel the boXom of your feet. This is mostly due to: a. The large recepEve fields of Merkel disks b. The rapid adapEng response of Pacinian corpuscles c. The small recepEve fields of Ruffini endings d. The slow adapEng response of Meissner corpuscles
b
298
Which statement is FALSE concerning touch receptors in the mouth and face? a. They are represented laterally in the dorsal column nucleus b. They project to the principal trigeminal nucleus via the trigeminal nerve c. Info converges with body touch informaEon in the dorsal thalamus d. Info is conveyed to the contralateral primary somatosensory cortex
a
299
You are looking at axon conducEon velocity and can't find any axons that conduct APs faster than 2 m/s. They are likely: a. A-alpha fibers b. A-beta fibers c. A-delta fibers d. C fibers
d
300
Which of the following statements is TRUE about the dorsal root ganglion (DRG)? a. It contains the cell bodies of motor neurons b. The cell bodies within the DRG are pseudounipolar in shape c. Cell bodies in the DRG do not have axons and give rise to just one dendrite d. Sensory axons from the DRG enter the spinal cord ventrally
b
301
Name the region of a rodent’s somatosensory cortex that represents the whiskers.
Barrel cortex
302
A small and rapid movement, most often of the eyes, is called a
Saccade
303
Consider the “bottom up” neural circuits for this: Name any three brain regions that are responsible for controlling this movement.
a. Superior Colliculus b. Saccade Generator region (either midbrain, pontine, or medullary reticular formation) c. Eye muscle motor neurons: (either oculomotor, trochlear, and abducens nuclei)
304
I am a region of the medulla where the first convergence of auditory information occurs. Specifically, I am responsible for measuring interaural time differences (ITDs)
Medial superior olive
305
I am a cortical area that lies anterior to the premotor cortex. I play a major role in controlling attention, specifically voluntary shifts in visual spatial attention. In particular, I am critical in helping to determine the location of your next saccade....
Frontal eye fields
306
I am an encapsulated nerve ending located deep in the dermis, among the sub- cutaneous fat. I have a large receptive field and, if you've been standing in one place for a while, you no longer feel sensation on the bottom of your feet because of me. But, when someone jumps nearby, causing vibrations in the floor, I will quickly respond.
Pacinian corpuscle
307
I’m a sensory nerve ending embedded in the tendon that can sense changes in muscle tension. I provide critical information about the force with which a muscle pulls on a tendon. If there’s too much tension, I will inhibit the muscle from creating any force to prevent injury.
Golgi tendon organ
308
I was a Canadian neurosurgeon who was performing brain surgery on patients to try to alleviate epilepsy. Because there are no pain receptors in the brain, I was able electrically stimulate regions of the cortex and ask awake patients where they felt sensations. I used this information to create a map-like representation of regions of the body in the brain.
Wilder Penfield
309
I am a region of the cortex, found directly adjacent (in a concentric ring) to A1. My neurons respond best to more complex characteristics of sounds, including processing rhythm and detecting a difference or anomaly in a melody.
Belt area (A2)
310
Following activation of a hair cell in the cochlea, information is going to travel along the (a) _____ branch of the (b) _____ cranial nerve to the brain.
(a) auditory nerve (or cochlear nerve) (b) vestibulocochlear (nVIII)
311
An opioid binds to a (a) _______ -coupled opioid receptor, which dissociates and activates the enzyme, (b) _______. This enzyme reduces production of the second messenger (c) _______ which causes Ca2+ channels to (d) (choose one) open / close and K+ channels to (e) (choose one) open / close. This change in ion flux causes a membrane (f) _______ when activated by an opioid
(a) g-protein (b) Adenylate cyclase (c) cAMP (d) close (e) open (f) hyperpolarization
312
What is the name for a long cilium that sits next to the tallest stereocilium of a vestibular hair cell?
Kinocilium
313
If you met a patient who could produce speech, but had lost the ability to comprehend it, what region of the brain in the language circuit do you predict has been damaged?
Wernicke’s area
314
1. Fluid inside the scala media is called (a) ___________ which has a (b) ______ concentration of K+ ions 2. Fluid inside surrounding the body of the hair cell is called (a) ___________ which has a (b) ______ concentration of K+ ions
1a. Endolymph 1b. High 2a. Perilymph 2b. Low
315
At high temperatures (43ºC) or when in contact with capsaicin, the _________ channel is activated.
TRP-V1
316
If nociceptors are activated following a sharp cut to your skin, information on the first pain will likely travel to the brain from via (a) ________ fibers along the (b) ____________ tract
a. Ad fibers b. Neospinothalamic tract
317
In a hair cell of the inner ear, what is the name for a type of chemical synapse in which numerous synaptic vesicles are arranged around a central electron dense structure that can tether 100 or more vesicles ready to be released?
Ribbon Synapse
318
Occlusion:
a cue relative to depth order in which one object obstructs the view of part of another object. If an object is closer to you, it will obstruct your view of the object behind it
319
Texture Gradient:
A depth cue based on the geometric fact that items of the same size form smaller images when they are further away. So, our visual system assumes objects of decreasing size are increasingly further away.
320
Relative Height
A depth cue where objects further away will be seen as higher on the image. So, the smaller image of a more distant object will be projected higher in your visual field
321
Aerial Perspective
a depth cue based on our implicit understanding that light is scattered by the atmosphere. More light is scattered when we look through more atmosphere, so objects farther away are subject to more scatter and appear fainter and less distinct
322
Linear Perspective
depth cue based on the fact that lines that are parallel in the 3D world will appear to converge in a 2D image as they extend into the distance towards a vanishing point
323
What is the term for an auditory distance cue based on the sound absorbing qualities of air, which dampen high frequencies more than low frequencies?
Spectral Composition