Exam 2 - Ch. 20 Flashcards
**Parameters of a Non-stress test
Monitor FHR for 20 minutes
Results:
Reactive = normal FHR, 2 accelerations of 15 bpm lasting 15 seconds
Non-reactive = absence of 2 accelerations of 15 bpm lasting 15 seconds in 20 minutes (more testing indicated)
***
Parameters of contraction stress test
Monitor FHR reaction to contractions (at least 3 in 10 min)
Positive (ABNORMAL) = FHR shows late decelerations w/ 50% or more of contractions
Negative = no late or significant variable decelerations
Equivocal-suspicious: intermittent late decels or significant variable decels
T/F: a contraction stress test is interpreted by presence/absence of late decelerations
True
**What are the components of a biophysical profile?
Non-stress Test (NST)
By ultrasound:
Fetal breathing
Fetal activity
Fetal muscle tone
Amniotic fluid volume (AFI)
**When is a BPP (biophysical profile) performed?
With a non-reactive non-stress test or with a high risk pregnancy.
What is the thin, tough sac of membrane that covers the embryo?
Amnion
What is the protective, filled with amniotic fluid, inner membrane that encircles the embryo?
Amnion
What is the outer membrane that surrounds the amnion?
The chorion
What serves as the support platform for fetus and amnion?
The chorion
What provides nutrient exchange from mother to fetus and is the foundation for embryonic development?
The chorion
What has the chorionic villi – barrier between maternal & fetal blood?
Chorion
The chorion is the barrier between the maternal and fetal what?
Blood
In multiple pregnancies, what type of presentation has less risk of cord entanglement?
If each fetus has own amniotic sac.
If each fetus in a multiple pregnancy does not have its own amniotic sac, what can happen that puts the fetuses at risk?
Cord entanglement
What is it called in a multiple birth when one fetus steals nutrition from the other when there is one placenta?
Twin-to-twin transfusion
There is one placenta in twin-to-twin transfusion and each fetus has it’s own what?
Amniotic sac
What chorion/amnion condition puts multiple fetuses at risk for twin-to-twin entanglement?
Monochorionic/monoamnionic
**What is a Multizygotic pregnancy?
2 or more eggs are fertilized at the same time
**What is a dizygotic pregnancy?
2 separate eggs fertilized = fraternal twins (2 genetically unique children)
70% of multiple pregnancies
**What is a zygote?
Fertilized ovum
**Risk factors for having a multizygotic pregnancy…
- Artificial reproductive technology (ART)
- Ethnicity (particularly African descent)
- Family history
- Advanced maternal age (↑FSH can cause release of >1 egg as menopause approaches)
Why does the chance of twins increase with maternal age?
↑FSH can cause release of >1 egg as menopause approaches
**All fetuses came from the same ovum in what type of multiple births?
Monozygotic
**Identical twins are from what type of multiple pregnancy?
Monozygotic
What determines # of amnions, chorions, placentas in a multiple pregnancy?
Time of ovum split
**T/F: A monozygotic split is a random / spontaneous event.
True
**What type of multiple pregnancy is not associated with a genetically inherited trait or ethnic group?
Monozygotic split
Typical discomforts of pregnancy are reduced or amplified in multiple pregnancies?
Amplified
Risks in multiple pregnancies:
gestational diabetes
hypertensive d/o, including preeclampsia
pulmonary embolism
preterm birth (50%)
perinatal mortality (3x more for twins, 4x more for triplets)
placenta previa
fetal anomalies
cord entanglement
twin-to-twin transfusion syndrome (50% higher mortality rate)
Hyperemesis gravidarum (HG) is characterized by what?
Unusually acute nausea and vomiting.
Unusually acute nausea and vomiting is called what?
Hyperemesis gravidarum (HG)
In what weeks of pregnancy is hyperemesis gravidarum usually present?
From weeks 11-20
In what condition are the following risks associated?
Weight loss
Malnutrition
Dehydration
Ketonuria
Electrolyte imbalances
Hyperemesis gravidarum
Treatments for hyperemesis gravidarum…
Rest
Possible anti-emetics (*see O’Meara Pharmacy table 20.1)
IV fluids
Parenteral nutrition
What is promethazine (Zofran) used for in pregnancy?
Relieving nausea/vomiting in hyperemesis gravidarum
What is Metroproclamide (Reglan) used for?
Relieving nausea/vomiting in hyperemesis gravidarum
What is ondansetron (Zofran) used for?
Relieving nausea/vomiting in hyperemesis gravidarum
What type of medication is the drug of last resort with hyperemesis gravidarum?
Corticosteroids
Risk factors for hyperemesis gravidarum.
History of HG
Gestational trophoblastic disease
Multiple pregnancies
Hyperthyroidism
GI disease prior to pregnancy
Depression/anxiety
Female fetus
What condition are the following symptoms indicative of?
History of the condition
Gestational trophoblastic disease
Multiple pregnancies
Hyperthyroidism
GI disease prior to pregnancy
Depression/anxiety
Female fetus
Hyperemesis gravidarum
A patient who is 13 weeks pregnant has experienced excessive vomiting for two weeks. Which of the following indicate dehydration?
Decreased heart rate
Decreased BP
Pedal edema
Poor skin turgor
Poor skin turgor
A miscarriage (AKA spontaneous abortion) occurs before what stage of gestation?
Before 20 weeks gestation
**A miscarriage, ectopic pregnancy, or gestational trophoblastic disease may present how?
Vaginal bleeding
When does implantation bleeding usually occur?
Usually around 6-11 days after fertilization, bright red or dark brown, lasting ~1 day
What type of gestational bleeding should be carefully evaluated?
All bleeding should be carefully evaluated.
At what point in gestation does miscarriage usually occur?
About 5-8 weeks
What is the likely cause of miscarriage?
Chromosomal abnormalities
What condition are the following risk factors for?
Advanced parental age
Drug/alcohol use
Poor maternal nutrition
Use of teratogenic meds
Certain maternal health conditions
Miscarriage
Nursing assessments for miscarriage
When was last period?
Vaginal bleeding assess color, clotting, contents, tissue?
Cramping?
HCG doesn’t double every 2-3 days (72 hours) for 8-11 weeks.
Nursing interventions for miscarriage
Emotional support
Risk of infection
Report all episodes of the following in miscarriage to indicate what?
Heavy bleeding
Fever
Foul-smelling discharge
Abdominal tenderness
Infection
**What is it called when a pregnancy develops outside the uterus, often in a fallopian tube?
Ectopic Pregnancy
**T/F: Ectopic pregnancies are considered non-life-threatening and a “watch and see” position is indicated.
False. Ectopic pregnancies are life-threatening and must be ended urgently
**What condition are the following indicative of?
Severe pelvic pain that may be unilateral (may refer to one shoulder)
Bleeding
Slow rise of Beta hCG levels
Ectopic pregnancy
**Can ectopic pregnancies be asymptomatic?
Yes.
At what point in pregnancy should the heart beat be seen on ultrasound?
6 weeks
**Do IUD’s contribute to ectopic pregnancies?
Yes.
**Ectopic pregnancy locations are:
Ovary
Fallopian tube
Intestine
Cervix
**An ectopic pregnancy in the cervix is likely caused by what?
Multiple pregnancies
**What are the risk factors for an ectopic pregnancy?
History of the condition
Pelvic infection
Pelvic surgery
Advanced maternal age (AMA)
Cigarette smoking
IUD (intrauterine device)
STI – gonorrhea and/or chlamydia
**What condition are the following indicative of?
History of the condition
Pelvic infection
Pelvic surgery
Advanced maternal age (AMA)
Cigarette smoking
IUD (intrauterine device)
STI – gonorrhea and/or chlamydia
Ectopic pregnancy
What drug ends pregnancy by inhibiting cell reproduction and DNA synthesis?
Methotrexate
**What is the drug of choice for an ectopic pregnancy?
Methotrexate
**Is surgery an option for removal of the ovum in an ectopic pregnancy?
Yes.
**How can the STI’s gonorrhea and chlamydia cause ectopic pregnancies?
Scarring
**What is the name of the procedure for removal of a fallopian tube?
Salpingectomy
**Is Rhogam administered to a woman with an ectopic pregnancy?
Yes, if she is RH-
**What to watch for in an ectopic pregnancy.
Heavy bleeding
Dizziness
Tachycardia
**What is the condition called when a nonviable mass is reproducing in the uterus?
Gestational trophoblastic disease (GTD)
**What’s another name for gestational trophoblastic disease?
Molar pregnancy
Failure of a fertilized egg to develop properly can be due to what 2 factors?
Fertilization of egg with no genetic material
2 sperm simultaneously fertilize 1 egg with normal genetic material
**Can trophoblastic tissue grow beyond the uterus?
Yes
**If trophoblastic tissue growing beyond the uterus is cancerous, what condition must be met before getting pregnant again?
All the cancer must be gone.
**How should cancerous trophoblastic tissue that is growing outside the womb be monitored after removal?
By HCG levels. In pregnancy, should double every 2-3 days (72 hours) for 8-11 weeks. If tissue is removed, should return to normal.
**What condition are the following assessments indicative of?
Abnormally rapid growth
Abnormally ↑ beta hCG
Ultrasound – “snowstorm” (no expected fetal structures)
Often experience vaginal bleeding
Molar pregnancy (gestational trophoblastic disease.
**What is the treatment for GTD?
D&C (dilation and curettage) to remove products of conception if not passed spontaneously.
**For how many months after a D&C to remove a GTD, should a woman avoid getting pregnant?
6-12 months
**What condition are the following signs indicative of?
Brownish vaginal bleeding
Uterine size large for gestational age
Nausea
GTD/Molar pregnancy
**Treatments for GTD/Molar pregnancy
D&C
Rhogam for Rh- woman
Emotional support
**Why should a woman who has had a D&C to remove a GTD watch for the following signs?
Heavy bleeding
Foul-smelling vaginal discharge
Abdominal pain and tenderness
Fever
Infection
**Conditions during the 1st trimester
Gestational trophoblastic disease (molar pregnancy)
Ectopic pregnancy
Miscarriage
Hyperemesis Gravidarum
Conditions of 2nd trimester in pregnancy:
Gestational Hypertension
Preeclampsia
Eclampsia
Gestational Diabetes Mellitus
TORCH infections
UTI
Cervical insufficiency
IUGR
Polyhydramnios
Oligohydramnios
**How is gestational hypertension diagnosed?
Systolic blood pressure ≥140 mm Hg &/or diastolic blood pressure ≥90 mm Hg without protein in the urine or signs of end-organ dysfunction after 20 weeks of pregnancy
**Up to half of the women diagnosed with gestational hypertension go on to develop what condition?
Preeclampsia
**What are the complications of gestational hypertension?
preterm birth
small for gestational age (SGA) infants
placental abruption
**How is preeclampsia diagnosed?
Patient with hypertension (≥ 140/90 mm Hg) on two occasions at least 4 hours apart AND has proteinuria
A BP of ≥ 160 systolic &/or ≥ 110 diastolic does not require a 4-hr wait between readings
OR
Patient has hypertension with or without proteinuria AND:
a platelet count <100,000
serum creatine >1.1 mg/dL
elevated liver enzymes
pulmonary edema –or-
new-onset visual or cerebral symptoms
**What is the following an indication of?
Patient with hypertension (≥ 140/90 mm Hg) on two occasions at least 4 hours apart AND has proteinuria***
Preeclampsia
**What condition are the following indicative of?
Patient has hypertension with or without proteinuria AND:
a platelet count <100,000 (thrombocytopenia)
serum creatine level >1.1 mg/dL (progressive renal insufficiency)
elevated liver enzymes (doubled)
pulmonary edema –or-
new-onset visual or cerebral symptoms
Preeclampsia
**What is the proteinuria level on a preeclampsia woman?
Proteinuria of at least +1
**At what time in gestation does a pregnant woman develop preeclampsia?
After 20 weeks
**Preeclampsia with tonic-clonic seizures is called what?
Eclampsia
**What causes preeclampsia?
Not well understood but may be:
- abnormal attachment of placenta
- abnormal pregestational maternal inflammation or epithelial cell functioning
**Risks from poor circulation (vasoconstriction) caused by preeclampsia are:
Oligohydramnios
Placental abruption
IUGR
**What is the treatment for patients at high risk of preeclampsia?
Aspirin and calcium supplements
**What is the treatment for mild preeclampsia and gestational hypertension?
Maybe be monitored on an outpatient basis
**What is the treatment for severe preeclampsia?
May have to be induced
**What medication is often given to patients with severe preeclampsia?
Magnesium sulfate is often given by IV to prevent seizures (reduces CNS irritability; can lower seizure threshold by ~50%) *AND given for neuroprotection for the fetal brain (decreased cerebral palsy)
**What type of protection does Mg Sulfate offer to the fetus?
Neuroprotection for the fetal brain (decreased cerebral palsy)
**How is Mg Sulfate administered?
IV
**What does Mg Sulfate do?
Prevents seizures