Exam 2 Flashcards

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1
Q

The region labeled “A” in the cartoon above

represents:

a. the protein component of a phospholipid
b. the cholesterol component of a phospholipid
c. the hydrophilic (polar) head group of a

phospholipid

d.the hydrophobic (nonpolar) head group of a

phospholipid

e.the hydrophobic (nonpolar) fatty acid tail of a

phospholipid

A

c.the hydrophilic (polar) head group of a

phospholipid

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2
Q

he region labeled “B” in the cartoon above

represents:

a. the protein component of a phospholipid
b. the cholesterol component of a phospholipid
c. the hydrophilic (polar) head group of a

phospholipid

d.the hydrophobic (nonpolar) head group of a

phospholipid

e.the hydrophobic (nonpolar) fatty acid tail of a

phospholipid

A

e.the hydrophobic (nonpolar) fatty acid tail of a

phospholipid

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3
Q

When phospholipids are placed in an aqueous

environment, they assemble into membranes. Which

of the following is true about a membrane?

a. It contains two layers of phospholipids with the

“B” regions facing the inside and the “A”

regions facing out.

b.It contains two layers of phospholipids with the

“A” regions facing the inside and the “B” regions facing out.

c. It contains a single layer of phospholipids with

the “B” region facing the inside and the A”

region facing out.

d. It contains a single layer of phosopholipids with

the “A” region facing the inside and the “B”

region facing out.

A

a. It contains two layers of phospholipids with the

“B” regions facing the inside and the “A”

regions facing out.

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4
Q

Why don’t Na+ ions move across the plasma membrane and down their concentration gradient all the time?

a. The plasma membrane is not permeable to Na+ ions.
b. The Na+/K+ pump is required and it only operates when ATP is plentiful.
c. A Na+ channel is required and it is usually closed.
d. A & C.
e. A, B, & C.

A

d. A & C.

The plasma membrane is not permeable to Na+ ions.

A Na+ channel is required and it is usually closed.

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5
Q

Which of the following is NOT TRUE about Na+ ion

channels?

a. They are proteins.
b. They are embedded in the plasma membrane.
c. They allow Na+ ions to move down their

concentration gradient.

d. They require energy in order to move Na+ ions.
e. They undergo a conformational change to open

or close.

A

d. They require energy in order to move Na+ ions.

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6
Q

Which of the following is NOT TRUE about the

Na+/K+ pump?

a. It is a protein.
b. It moves Na+ ions against their concentration

gradient.

c.The hydrolysis of ATP results in the Na+/K+

pump changing what side of the plasma

membrane it is open to.

d. The hydrolysis of ATP results in the Na/K+

pump changing its affinity for Na+ ions.

e.The pump has a high affinity for Na+ ions when

it is open to the outside of the cell.

A

e.The pump has a high affinity for Na+ ions when

it is open to the outside of the cell.

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7
Q

Which of the following is NOT an organelle with a membrane?

a. nucleus
b. rough endoplasmic reticulum
c. smooth endoplasmic reticulum
d. ribosome
e. Golgi

A

d. ribosome

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8
Q

Which of the following is present in plant cells, but

not animal cells?

a. plasma membrane
b. cell wall
c. Golgi
d. A&B
e. B&C

A

b.cell wall

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9
Q

Glucose is in lower concentration inside the fat cell

than outside. This is…

a. A concentration gradient
b. Facilitated diffusion
c. Activation energy
d. Impossible

A

a. A concentration gradient

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10
Q

Under these conditions, glucose would enter the fat

cell through the transporter by…

a. Diffusion
b. Facilitated diffusion
c. Active transport
d. Endocytosis
e. Exocytosis

A

b.Facilitated diffusion

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11
Q

Which of the following is TRUE about the synthesis

of the insulin protein?

a.Insulin is synthesized by ribosomes floating free

in the cytoplasm.

b.Insulin is synthesized by ribosomes attached to

the rough ER.

c.Insulinis synthesized by ribosomes attached to

the smooth ER.

d.Insulin is synthesized by ribosomes attached to

the Golgi.

A

b.Insulin is synthesized by ribosomes attached to

the rough ER.

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12
Q

The insulin protein goes through the secretory pathway in the B-islet cells, but is not immediately secreted out of the cell. Instead, the protein is packaged in a vesicle that waits in the cytoplasm for a signal that insulin is needed in the blood. When that signal arrives, the vesicle fuses with the plasma membrane, thereby releasing insulin out of the cell.

This vesicle fusion is an example of:

a. sorting
b. endocytosis
c. exocytosis
d. diffusione.
e. facilitated diffusion

A

c.exocytosis

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13
Q

If insulin has not folded into its proper conformation,

it cannot bind to the insulin receptors. A protein’s

conformation (or functional shape) refers to its:

a. primary structure
b. secondary structure
c. tertiary structure
d. quaternary structure

A

c.tertiary structure

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14
Q

Insulin is made up of two alpha helixes, which are

examples of _____.

a. primary structure
b. secondary structure
c. tertiary structure
d. quaternary structure

A

b.secondary structure

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15
Q
A

A

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16
Q

What type of interactions would serine most

likely participate in?

a. van der Waal’s interactions
b. ionic bonds
c. covalent bonds
d. hydrogen bonds

A

d.hydrogen bonds

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17
Q

When glucose enters the cells it enters glycolysis.

Which of the following is NOT true about glycolysis?

a. it occurs in the cytoplasm.
b. It occurs under both anaerobic and aerobic

conditions.

c.It makes a few ATP molecules by oxidative

phosphorylation.

d.It completely oxidizes the carbons in glucose to

carbon dioxide.

e.C & D

A

c.It makes a few ATP molecules by oxidative

phosphorylation.

d.It completely oxidizes the carbons in glucose to

carbon dioxide.

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18
Q

The first reaction in glycolysis is catalyzed by the enzyme hexokinase and it converts the substrates glucose and ATP to glucose-6-phosphate and ADP. The reaction is shownbelow.

glucose + ATP ↔ glucose-6-phosphate + ADP

This reaction is part of the _________ phase of

glycolysis.

a. energy investment
b. cleavage
c. energy release
d. reduction
e. oxidation

A

a.energy investment

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19
Q

The first reaction in glycolysis is catalyzed by the enzyme hexokinase and it converts the substrates glucose and ATP to glucose-6-phosphate and ADP. The reaction is shownbelow.

glucose + ATP ↔ glucose-6-phosphate + ADP

Which of the following is NOT TRUE about

hexokinase?

a. it speeds up the reaction.
b. It is not consumed in the reaction.
c. It lowers the activation energy of the reaction.
d. It lowers the G of the reaction.

A

d.It lowers the G of the reaction.

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20
Q

Which of the following is TRUE about the active site?

a.It is the region on the enzyme where substrates

bind.

b. It is the region on the substrate that binds to enzyme.
c. It has special properties that stimulate reactions

in the substrate

d. A & C
e. B & C

A

d.A & C

.It is the region on the enzyme where substrates

bind.

It has special properties that stimulate reactions

in the substrate

21
Q

Glucose is soluble in water because it can form ___

with water molecules.

a. Covalent bonds
b. Hydrogen bonds
c. Ionic bonds
d. Hydrophobic bonds

A

b.Hydrogen bonds

22
Q

How would a fat cell

store any excess glucose it took

up?

a. As glycogen
b. As cellulose
c. The glucose would be broken down to pyruvate,

which would then be combined to form fat.

d. The glucose would be broken down to acetyl

CoA, which would then be combined to form fat.

e.The glucose would be broken down to carbon dioxide, which would then be combined to form

fat.

A

d. The glucose would be broken down to acetyl

CoA, which would then be combined to form fat.

23
Q

Which is/are the least oxidized (burned)?

a. Carbohydrate
b. Protein
c. Fat
d. A and B
e. All are the same.

A

c.Fat

24
Q

Which binds the least water?

a. Carbohydrate
b. Protein
c. Fat

A

c.Fat

25
Q

Is the conversion of malate to oxaloacetate an

oxidation or reduction?

a. oxidation
b. reduction

A

a.oxidation

26
Q

beer contains alcohol that was

made by yeast under which conditions?

a. A lack of glucose
b. A lack of oxygen
c. A lack of pyruvate
d. A lack of carbon dioxide
e. A lack of sunlight

A

b.A lack of oxygen

27
Q

Alcohol that you drink can be converted into which of

the following?

a. Lactic acid
b. Pyruvate
c. Glucose
d. Protein
e. Fat

A

e.Fat

28
Q

Which list of pathways is in the correct order for

metabolism of glucose?

a. Glycolysis, Krebs cycle, electron transport
b. Glycolysis, electron transport, Krebs cycle
c. Krebs cycle, electron transport, Glycolysis
d. Krebs cycle, Glycolysis, electron transport
e. Electron transport, Glycolysis, Krebs cycle

A

a.Glycolysis, Krebs cycle, electron transport

29
Q

Fats are first broken down into acetyl CoA.

a. True
b. False

A

A true

30
Q

When you exercise, ATP is used to make your

muscles contract. Conversion of ATP to ADP and

phosphate is which type of reaction?

a. Aerobic
b. Anaerobic
c. Exergonic
d. Endergonic
e. Exocytotic

A

c.Exergonic

31
Q

How does oxygen enter cells?

a. Osmosis
b. Diffusion
c. Active Transport
d. Facilitated diffusion
e. Endocytosis

A

b.Diffusion

32
Q

Lactic acid is made from which of the following?

a. Glucose
b. Acetyl CoA
c. Fat
d. Protein
e. Pyruvate

A

e.Pyruvate

33
Q

Why did your body make lactic acid that caused your

cramps?

a. To regenerate NAD+ to keep glycolysis going.
b. To increase oxygen uptake
c. To produce NADH to keep the Krebs cycle

going.

d. To increase glucose uptake into muscle cells.
e. To increase insulin secretion.

A

a.To regenerate NAD+ to keep glycolysis going.

34
Q

The electron transport chain used to break down food

is found in which organelle?

a. Nucleus
b. Mitochondria
c. Lysosome
d. Chloroplast
e. Cytoplasm

A

b.Mitochondria

35
Q

Carbon monoxide, CO (C O), is formed by the incomplete combustion (burning) of fuels including natural gas and gasoline. Carbon monoxide can be lethal, inhibiting the last step in the electron transport chain (ETC).

What is probably meant by incomplete combustion?

a. Carbon was reduced in forming CO
b. Carbon was not oxidized in forming CO
c. Carbon monoxide is more oxidized than CO2
d. Carbon monoxide is less oxidized than CO2
e. Too much oxygen was present during

combustion

A

d.Carbon monoxide is less oxidized than CO2

36
Q

Carbon monoxide, CO (C O), is formed by the incomplete combustion (burning) of fuels including natural gas and gasoline. Carbon monoxide can be lethal, inhibiting the last step in the electron transport chain (ETC).

Carbon monoxide would inhibit which process?

a. NAD+ donating electrons to the ETC
b. NADH donating electrons to the ETC
c. H2O accepting electrons from the ETC
d. O2accepting electrons from the ETC
e. CO2 accepting electrons from the ETC

A

d.O2accepting electrons from the ETC

37
Q

Carbon monoxide, CO (C O), is formed by the incomplete combustion (burning) of fuels including natural gas and gasoline. Carbon monoxide can be lethal, inhibiting the last step in the electron transport chain (ETC).

Blocking a step in the ETC would directly

a. Prevent H+ ions from moving through ATP synthase
b. Prevent the formation of a H+ion gradient
c. Allow H+ions to spontaneously diffuse across

the membrane

d. Block the oxidation of glucose
e. Block fermentation

A

b.Prevent the formation of a H+ion gradient

38
Q

Carbon monoxide, CO (C O), is formed by the incomplete combustion (burning) of fuels including natural gas and gasoline. Carbon monoxide can be lethal, inhibiting the last step in the electron transport chain (ETC).

The ETC is found in which location?

a. Inner mitochondrial membrane
b. Outer mitochondrial membrane
c. Matrix of the mitochondria
d. Cytoplasm
e. Plasma membrane

A

a.Inner mitochondrial membrane

39
Q

Carbon monoxide probably crosses membranes by

a.Diffusion that doesn’t require a protein

channel

b. Diffusion requiring a protein channel
c. Active transport
d. A and C
e. B and C

A

a.Diffusion that doesn’t require a protein

channel

40
Q

Which is the first step in the ETC?

a. NAD+ donating electrons to the ETC
b. NADH donating electrons to the ETC
c. H2O donating electrons from the ETC
d. O2 donating electrons from the ETC
e. CO2 donating electrons from the ETC

A

b.NADH donating electrons to the ETC

41
Q

Energy released from electrons passing through the

ETC is used to directly do which of the following?

a. Make ATP
b. Pump H+ions across a membrane
c. Oxidize CO2
d. Oxidize pyruvate
e. Reduce NADH

A

b.Pump H+ions across a membrane

42
Q

The neurotransmitter Norepinephrine (NE) is released from neurons, and has been reported to reduce neuronal excitability and act as an anticonvulsant. The NE transporter (NET) is a protein embedded in the membrane of neurons that release NE. NET deficient knock-out mice (NET-KO) are characterized by high levels of NE in the synapse. NET-KO mice were used to investigate the role of NE in cocaine-induced convulsions.

How do neurotransmitters normally function?

a.They are released into the synapse from one

neuron by exocytosis and bind to a receptor on

another neuron.

b.they are released into the synapse from one

neuron through an ion channel and bind to a

receptor on another neuron.

c.They are released into the synapse from one

neuron by exocytosis and enter another neuron

through an ion channel.

d.They are released into the synapse from one

neuron through an ion channel and enter another

neuron through an ion channel.

e.They are released into the synapse from one

neuron by exocytosis and enter another neuron

through endocytosis.

A

a.They are released into the synapse from one

neuron by exocytosis and bind to a receptor on

another neuron.

43
Q

The neurotransmitter Norepinephrine (NE) is released from neurons, and has been reported to reduce neuronal excitability and act as an anticonvulsant. The NE transporter (NET) is a protein embedded in the membrane of neurons that release NE. NET deficient knock-out mice (NET-KO) are characterized by high levels of NE in the synapse. NET-KO mice were used to investigate the role of NE in cocaine-induced convulsions.

Based on the text,

which of the following is most

likely true?

a.Norepinephrine is released into the synapse by

the NE transporter.

b.Norepinephrine is reabsorbed from the synapse

by the NE transporter.

c.Norepinephrine enters a neuron by facilitated

diffusion, causing it to become excited.

d.Norepinephrine is digested in the synapse by the

NE transporter.

e.Norepinephrine is synthesized in the synapse by

the NE transporter.

A

b.Norepinephrine is reabsorbed from the synapse

by the NE transporter.

44
Q

Convulsions triggered by cocaine were compared in knockouts (NET-KO = no copies of the NET gene), heterozygous (NET-HT = one copy of the NET gene) and wild type (NET-WT = two copies of the NET gene) female mice. Mice with different numbers of NET genes were injected with increasing concentrations of cocaine, and the percent suffering from convulsions was measured

What are the dependent (DEP) and independent (IND) variables in the experiment?

a. DEP=the amount of cocaine injected, IND=the percent of mice with convulsions when exposed to cocaine.
b. DEP=the number of NE transporter genes, IND=the percent of mice with convulsions when exposed to cocaine.
c. DEP=the percent of mice with convulsions when

exposed to cocaine, IND=the number of NE

transporter genes.

d. DEP=the number of NE transporter genes,

IND=the amount of cocaine injected.

e. DEP=the amount of cocaine injected, IND=

thenumber of NE transporter genes.

.

A

c. DEP=the percent of mice with convulsions when

exposed to cocaine, IND=the number of NE

transporter genes.

45
Q

What conclusions about the NE transporter can be drawn from the graph above?

a. The NE transporter normally increases sensitivity to cocaine.
b. The NE transporter normally decreases sensitivity to cocaine.
c. The NE transporter has no affect on sensitivity to cocaine.

A

a.The NE transporter normally increases sensitivity to cocaine.

46
Q

Cocaine has a similar structure to norepinepherine. How might cocaine cause convulsions?

a. It enters a neuron through an ion channel, causing the neuron to fire.
b. It binds to a receptor on a neuron, opening an ion channel and thus causing the neuron to fire.
c. It blocks an ion channel, preventing a neuron from firing.
d. It binds to a receptor on a neuron, closing an ion channel and thus causing the neuron to fire.
e. It enters a neuron by endocytosis, causing the neuron to fire.

A

b. It binds to a receptor on a neuron, opening an ion channel and thus causing the neuron to fire.

47
Q

Neurons require a lot of ATP for which process?

a. Pumping oxygen into the neuron.
b. Pumping CO2 out of the neuron.
c. Pumping Na+ into the neuron.
d. Pumping Na+ out of the neuron.
e. Pumping glucose into the neuron

A

d.Pumping Na+ out of the neuron.

48
Q
A