Exam 2 Flashcards
How many known vitamins are there?
14
What are the fat-soluble vitamins?
- Vitamin A
- Vitamin D
- Vitamin E
- Vitamin K
What are the water-soluble vitamins?
• B-complex vitamins □ Thiamine (vitamin B1) □ Riboflavin (vitamin B2) □ Niacin (Vitamin B3) □ Vitamin B6 (pyridoxine) □ Folate □ Vitamin B12 □ Biotin □ Pantothenic acid • Vitamin C • Choline (vitamin-like compound)
What are the B Vitamins?
- thiamine
- riboflavin
- niacin
- vitamin B6
- folate
- vitamin B12
- biotin
- pantothenic acid
What are vitamins?
- Organic compounds (Contain both carbon-carbon and carbon-hydrogen bonds)
- Micronutrients
- Essential nutrients (must be consumed in the diet)
- Individual units
- Are not a source of energy (calories)
Why are vitamins needed?
to extract energy from macronutrients
How are vitamins classified?
according to their solubility
What does solubility determine?
how vitamins are absorbed and transported in body
What does a vitamin’s solubility affect?
where vitamins are stored and risk for toxicity
What are some common characteristics of fat-soluble vitamins?
- Insoluble in water
- Dissolve in lipids
- Small amounts needed
- Absorption in small intestine
- Leave small intestine in chylomicrons
- Stored in tissue
- Potential for toxicity
- Often present in fatty portion of foods
What is Vitamins A’s primary function?
vision and cell differentiation, function as hormones
What is Vitamin D’s primary function?
bone growth and maintenance, cell development, immunity
What is Vitamin E’s primary function?
antioxidant
What is Vitamin K’s primary function?
blood clotting and bone formation
How is vitamin D produced?
in the skin from cholesterol adn exposure to UV light
What is Vitamin D’s nickname?
sunshine vitamin
Why is it essential to consume vitamin D?
insufficient sun exposure
Can Vitmain D be consumed through the diet?
yes
How can vitamin D be activated in the body?
Must be activated in the kidneys and liver to function in the body
What are the richest sources of vitamin D?
fatty fish and fish liver oil
Does Vitamin D occur naturally in many foods?
no, besides fish
What is the most common source of Vitamin D in the US Diet?
fortified foods
What does Vitamin D primarily function as?
a hormone
What are the functions of Vitamin D in the body?
- Acts as a hormone
- Helps bone growth and maintenance
- Regulates calcium metabolism
* Blood levels- Absorption
- Excretion
- Regulates the synthesis of certain proteins
- Possibly regulates cardiovascular function
- Ongoing research of other roles in the body
What groups are at risk of Vitamin D deficiency?
- avoid vitamin-D fortified foods
- people with dark skin
- inadequate sun exposure
- exclusively breast-fed infants
- elderly
Is Vitamin D a nutrient of concern?
yes
Why are the elderly at risk of vitamin D deficiency?
○ Reduced ability to synthesize vitamin D
○ Reduced sun exposure
○ Potential diminished intake
What can extremely low levels of vitamin D cause overtime?
rickets, osteomalacia
What group of fat-soluble compounds does Vitamin A encompass?
retinoid compounds and carotenoids
What are the types of retinoid compounds?
Retinal, Retinol, Retinoin acid
What is the only retinoid present in significant amounts in our diet?
retinol
What is retinol called and why?
Called preformed Vitamin A as already in active form in foods
What are carotenoids?
Provitamin as only has vitamin activity after conversion to active form in the body
What is the primary carotenoid in our diet?
beta-carotene
What does the bioavailability of Vitamin A differ upon?
food source
What are sources of provitamin A carotenoids?
Yellow-, orange-, and red-pigmented fruits and vegetables
Where are preformed vitmain A founds?
animal foods and fortified foods
What is different about preformed vitamin A?
more readily absorbed
What unit is the RDA given in for retinol?
Retinol Activity Equivalents (RAE)
Why is the RDA for retinol in RAE?
- Conversion of beta-carotene to retinol is never complete
* Absorption of carotenoids from food is poor
How can you improve the bioavailability of retinoids?
slicing, chopping, cooking, juicing and cooking
Where is most Vitamin A consumed in the US diet?
preformed sources (animal foods)
What are the critical biochemical and physiological functions of vitamin A in the body?
vision
functions as hormone
How does beta-carotene play an important role?
potent antioxidant properties
What are plant forms of Vitamin A?
carotenoids and beta-carotene
What do carotenoids and beta-carotene function as?
antioxidants
What do antioxidants help with?
Help protect cells from oxidative damage caused by reactive molecules called free radicals
What do high levels of free radicals cause?
cellular damage
What is the leading cause of blindness in children worldwide?
vitamin A deficiency
What does hypovitaminosis A cause?
- Night blindness
- Permanent blindness
- Impaired immunity
What can consuming too much vitamin A cause?
hypervitaminosis A
Who especially needs to be cautious of excess vitamin A and why?
pregnant women - can cause birth defects
Does excess beta-carotene from plant sources cause toxicity?
no
What are the best sources of vitamin E?
nuts and some oils
What is one good source of vitamin E?
almonds
What does vitamin E function as?
an antioxidant within cellular membranes
What is vitamin E less toxic than?
vitamin A and D
Where is a significant amount of our Vitamin K produced by?
intestinal bacteria
What are dietary sources of Vitamin K?
leafy greens, some fruits, some cheese, some oils
What does vitamin K play a key role in?
blood clotting
What does vitamin K reduce the risk of?
hemorrhage in newborns
What is a standard procedure at birth?
to provide vitamin K injection or oral medication
What are characteristics of water-soluble vitamins?
- Dissolve in water
- Small amounts needed
- All except choline function as coenzymes
- Most circulate freely in blood
- Can be destroyed or removed during food storage or preparation
- Not stored in large amounts, low risk toxicity
Why do water-soluble vitamins have a low risk of toxicity
- excess generally excreted in urine
- excess generally from supplements not food sources
How do B vitamins differ?
each has a distinct structure and function
What do B vitamins function as?
coenzymes in chemical relactions
What do B vitamins help to accomplish?
chemical reactions that release energy from carbohydrates, proteins and fats
What is a coenzyme?
a compound that binds to a protein (enzyme) and is required for its function
What is Thiamin’s function?
coenzyme form in energy metabolism
What does a deficiency in thiamin cause?
beriberi
What does beriberi cause?
Causes muscle wasting, fatigue, and mental disturbances
What does niacin deficiency cause?
pellagra
what are symptoms of pellagra?
- Fatigue
- Dermatitis
- Diarrhea
- Mental deterioration
- Death
What is niacin’s function?
energy metabolism
How do people get excess intake of B vitamins?
through supplements
What products are fortified or enriched with B vitamins?
grain products
What is fortification?
addition of nutrients
What is enrichment?
replace nutrients extracted from grains when they are refined
What can B vitamins lower?
lower cholesterol
How does riboflavin function as?
energy metabolism
What are good sources of riboflavin?
milk and dairy foods
What destroys riboflavin?
UV Light
Where is riboflavin deficiency typically seen?
chronic alcohol abuse
Does riboflavin deficinecy typically occur on its own or with other deficiencies?
with other b vitamin deficiencies
What is B6’s function in the body?
coenzyme
What is Pantothenic acid’s role?
energy metabolsim
What is the RDA for folate?
400 mcg
What is the other form of folate?
folic acid
What are the functions of folate?
- Acts as a coenzyme in metabolism of certain amino acids
- Helps in DNA and RNA synthesis
- Helps with normal cell division and development
Where is folic acid found?
supplements and fortified foods
What does folate deficiency cause?
megaloblasic anemia
What does adequate intake of folate or folic acid prior to conception prevent?
2/3 of neural tube defects
What helps women reach the RDA for folate?
enriched grain products
What is B12 bound to?
proteins
What does B12 require for absorption?
acid and intrinsic factor in stomach
What does B12 act as?
a coenzyme
Where is B12 found naturally?
foods of animal origin
What does B12 deficiency cause?
megaloblasic anemia
What is B12 metabolism closely linked with?
folate
What are symptoms of megaloblasic anemia?
○ Increased fatigue during physical activity
○ Tingling or lack of sensation in legs and arms
○ Cognitive impairment and problems with motor control
What groups are at risk of B12 deficiency?
- Vegans (consume no animal foods)
- Gastric bypass patients
- Individuals with pernicious anemia (lack intrinsic factor)
- Elderly
What does risk of B12 deficiency increase with?
age
What are age related risk factors for B12 deficiency?
- Diminished intake
- Impaired absorption
- Reduced gastric acid and intrinsic factor
What is choline?
a vitamin-like compound classified as an essential nutrient
Can the body synthesize choline?
yes
What are the functions of choline?
Intertwined with function of folate and vitamin B12
What is Vitamin C also known as?
ascorbic acid
What are the functions of Vitamin C?
- Acts as coenzyme in biological reactions
- Aids in hormone production
- Involved in collagen synthesis
- Enhances iron absorption
- Antioxidant
Where is vitamin c found?
many fruits and some vegetables
Why do you need to be careful with vitamin C?
readily destroyed by storage and cooking
What does Vitamin C deficiency result in?
scurvy
What does Vitamin C intake above the UL cause?
GI issues
What is the RDA for Vitamin C for Men?
90 mg
What is the RDA for Vitamin C for women?
75 mg
What is the UL for Vitamin C?
2000 mg
What does overconsumption of vitamin C cause?
diarrhea, bloating
What defined “Dietary Supplement”?
Dietary Supplement Health and Education Act (DSHEA) of 1994