Exam 2 Flashcards
Hemizygous
In a diploid organism, the presence of only one copy of a gene.
Heterogametic chromosomes
XY chromosomes
What drives Maleness and Femaleness ?
there are genes on the X chromosome that drive “femaleness”, and ALSO genes that can drive “maleness” – but the male genes are only activated if genes on the Y chromosome are expressed.
cortex tissue
outer tissue, may develop into an ovary
medulla tissue
inner tissue, may develop into testis
bipontetial gonads
gonadal ridges that can either form testis or ovaries
pseudoautosomal regions (PAR’s)
-present on both ends of the y chromosomes
-share homology with regions on the X chromosome
(synapse and recombine with it during meiosis)
TDF
- Testis determining factor
- transcription factor that activates expression of many other genes even on X chromosomes
“located on the Y chromosome but influences expression of genes on the X chromosome”
What leads to male differentiation?
Expression of genes on Y chromosome leads to male differentiation
SRY expression leads to testes development
SRY genes code for ?
TDF