Exam #2 Flashcards

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1
Q

Numbers alive in 2000 US population (000) who would have suffered various fates if 1900 mortality conditions prevailed (White and Preston 1996)?

A
Hypothetical Total Deaths
137,277	50% of actual pop.
Been born and died (direct deaths)
68,441		25% of actual pop.
Had mothers who died before their birth
38,096		14% of actual pop.
Had grandmothers who died before mother’s birth
22,573		8% of actual pop.
Had earlier ancestor die
8,167		3% of actual pop.
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2
Q

Selected life expectancy figures:

A
Pre-history (before 1300)	20-25 years
Greeks, Romans		20-30
British aristocrats 	
	1330 – 1650 			30
England 		
	1600-1750			35
	1800-1850			39
	1900				47
	1990				75
	2010				80.1
U.S.
	1900				48
	2010				78.7
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3
Q

Life expectancy at birth, 2011:

A

Range: Sierra Leone 47 to Japan 83
Global average: 70 years

Points of Reference:
U.S. (78.7), Canada (82), Mexico (75)

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4
Q

Classification of Causes of Death (WHO):

A
  • Infectious and parasitic diseases
  • Degenerative or chronic diseases
  • Products of the social and economic environment
  • Reductions in death rates from infectious and parasitic diseases led to dramatic mortality decline.
  • Historically, mortality improvements occurred among young. Today, improvements are concentrated among old.
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5
Q

Hunter-gatherer societies:

A

Life expectancy = low 20s

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6
Q

Golden Age of Bacteria (1300-1650):

A

Exchange of diseases among populations newly in contact
- Smallpox
- Syphilis
The Plague

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7
Q

1650 - 1850:

A

Population growth begins as mortality rates start to decline slowly

Factors responsible for mortality decline (Europe):

  • Disappearance of plague
  • Agricultural revolution

Medical technology

  • Smallpox vaccination developed purely by observation
  • No theory of disease was developed at this time
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8
Q

What accounts for mortality decline after 1850?

A

Economic growth leading to improved nutrition and increased standards of living
Medicine
Public and private preventive measures

These explanations are not mutually exclusive and their relative importance has been of much contention.

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9
Q

Mortality decline due to economic growthThomas McKeown: Modern Rise in Population (1976):

A

For multiple diseases, bulk of mortality decline occurred BEFORE effective drugs became available .

Concluded that economic growth (which led to improved nutrition) must be responsible but provided no direct proof.

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10
Q

Mortality decline due to economic growth (Robert Fogel):

A

Found a close connection between improved nutritional status (e.g. height) and lower mortality

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11
Q

Miasma Theory:

A

A representation of the cholera epidemic of the 19th century depicts the spread of the disease in the form of poisonous air.

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12
Q

Public and Private Preventive Measures:

A

Germ theory of disease replaces miasma theory (1870s) and led to a series of public and private health initiatives

Public Health Initiatives

  • Water sewer systems and sewage disposal improvements
  • Pasteurization of milk
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13
Q

Private Health Initiatives:

A

Better Mothering Campaigns
- “We’ve discovered that the source of most diseases is not outside the home in public spaces, but inside the home. You’re making one another sick. Mothers, it’s your responsibility to maintain hygienic conditions and save your babies. Here’s what you can do.”

Formation of Children’s Bureau (1912)

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14
Q

Main Points:

A

Dramatic improvements in life expectancy over time since 1850s
Through transition, major causes of death change from infectious to noninfectious, chronic diseases
MDRs have completed the mortality transition
Much of MDR decrease in mortality occurred BEFORE modern medical advances, so medicine is NOT seen as a primary explanation for the decline.
Although debate continues, most demographic and medical historians conclude that mortality declined largely because of public and private health interventions. Rising standards of living as part of economic growth also played a role.

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15
Q

Epidemiological TransitionOmran, 1971:

A

Basic Components
High and fluctuating mortality and low life expectancy caused by infectious disease replaced by low, stable mortality and high life expectancy
Degenerative and manmade diseases become major causes of death
A shift in mortality from young to old ages.

Increase in life expectancy is implicit in these changes.

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16
Q

Three possible models:

A
  • The Classical or Western Model
    Gradual transition due to combination of economic growth, public health, medicine
  • The Accelerated Model
    More rapid transition due largely to public health and medical measures as well as social improvements
  • The Contemporary Delayed Model
    Recent, yet to be completed transitions in LDRs
    Public health and medical measures play key role
17
Q

Key factors in producing mortality decline in LDRs:

A

Public health initiatives

  • Most important is the eradiation of disease-carrying insects/rodents (e.g. DDT and malaria)
  • Water sewage improvements
18
Q

Routes to Low Mortality in LDRs Three countries were particularly successful in lowering mortality rates quickly: Kerala, India; Sri Lanka; Costa Rica

A
  • Important cultural factors
    Female autonomy, emphasis on education, egalitarian
  • Health services
    Relied on immunization campaigns, nutritional floors, household visits rather than expensive technology
  • Created important symbiosis between health services and culture - importance of women’s schooling
19
Q

Routes to Low Mortality in LDRs

A

Alternative routes to mortality:

  • China; Cuba; Vietnam
  • Devoted large resources to health sector. Achieved lower mortality through sheer political will.

Update (Kuhn, 2010)

  • Success in Latin America – role of cost-effective primary care programs, increasing democratic inclusion, conflict resolution
  • Recent reductions in Muslim world (e.g. Bangladesh) – targeted investments in health systems, narrowing of male/female schooling gap, reliance on human capital rather than resources
20
Q

The importance of women:

A
  • Women’s education is a strong predictor of child mortality.
  • Strong effect on infant mortality rates.
21
Q

Remaining problems in LDRs:

A
  • Increase in death rate from chronic diseases
  • Infant mortality
  • Sex differentials in mortality
22
Q

Remaining Challenges in High IMR countries:

A

Effectively implementing preventive measures
- Diarrhea; immunization; respiratory infections; malaria; perinatal causes

Need to focus resources on preventive care rather than curative medicine

23
Q

Why the excess female child mortality?

A

No biological cause

Rather, excess mortality results from a pattern of relative neglect of female children in some countries

  • Less nutrition and medical care for girls
  • Deep cultural underpinnings
24
Q

Cohort life table?

A

Follows a group of individuals (cohort) from birth to death to record their actual mortality experiences. Useful for many epidemiological/medical applications, but less useful for demographers

25
Q

Period life table?

A

Life table based on a hypothetical (“synthetic”) cohort, using age-specific mortality rates from a given year

26
Q

Short period advances in life expectancy?

A

World life expectancy has more than doubled in the past 200 years.

  • From about 25 years to 65 years for men
  • From about 25 years to 70 years for women
27
Q

Senescence? Its two modern biological theories?

A

physical condition of the body declines and person becomes more susceptible to disease.

  • Programmed theories – we age by design
  • Damage or error theories – we age because we experience wear and tear on our bodies
28
Q

Planned Obsolescence or Gene Expression Theory of Aging?

A
  • Aging follows a biological timetable
  • The number of repeats in a telomere determines maximum life span of a cell
  • May explain why we see variation in life expectancy across species
29
Q

Damage/Error Theories or Stochastic Theory of Aging?

A
  • Humans wear out due to stresses and strains of constant use
  • Emphasizes environmental factors that may accelerate the aging process
  • Helps us to understand why we may see variation in life expectancy within a species
30
Q

Two views on life expectancy?

A

Limited: A glass ceiling on life expectancy (Olshansky)

Unlimited: No inherent limits to life expectancy (Vaupel)

31
Q

How to extend the human lifespan?

A

Develop better treatments and medication for major killers. (We die because we get sick)

  • Cancer cures
  • Replace damaged body parts with stem cell therapies.

Slow down the aging process at the molecular and cellular levels. (We die because we get old)