Exam 2 Flashcards

1
Q

What is a AAA

A
  • permanent, localized, outpouching or dilation of wall of aorta
  • AAA more common: 3/4 of aortic aneurysms
  • occur in men more, increases with age
  • most occur below renal arteries
  • larger aneurysm = greater risk of rupture
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2
Q

Clinical manifestations of AAA

A

often asymptomatic
- can have mimicking abdominal or back disorder symptoms
- deep constant pain in abdomen
- low BP
- pulsation in belly button
- “blue toe syndrome”

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3
Q

Causes and risk factors of AAA

A

Causes:
- degenerative
- congenital
- mechanical: penetrating or blunt trauma
- inflammatory
- infectious

Risk factors:
- age, male gender
- HTN, CAD
- family history
- tobacco use
- high cholesterol
- lower extremity PAD
- carotid artery disease
- previous stroke
- excess weight or obesity

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4
Q

Treatment of AAA: small vs larger

A

Small aneurysm: size < 5.4 cm
- conservative therapy
- risk factor modification (lower BP, tobacco cessation, optimize lipid profile, gradual increase in activity)
- sizing 4-5.4cm: monitor every 6-12 months
- size < 4cm: ultrasound every 3 years

Larger than 5.5 cm:
- surgical repair
- can happen earlier in those with genetic disorder, rapidly expanding aneurysm, symptomatic patients, high rupture risk

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5
Q

Nursing care and education for AAA

A
  • watch for signs of cardiac, pulmonary, cerebral and lower extremity vascular problems
  • establish baseline data to compare postop
  • signs of aneurysm rupture
  • quality and character of peripheral pulses; mark pedal pulses and any lesions before surgery
  • monitor renal and neuro status

Goals:
- normal tissue perfusion
- intact motor and sensory function
- no complications related to surgical repair (thrombosis, infection, rupture)

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6
Q

PAD vs PVD

A
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7
Q

Clinical manifestations of PAD

A

symptoms occur when arteries are 60-75% blocked
- classic symptom: intermittent claudication
– ischemic muscle pain caused by constant level of exercise
– resolves with rest
– reproducible
- paresthesia
- cold legs
- thin shiny taut skin, no hair
- diminished pulses
- pallor w/ leg elevation, pain w/ elevation, hang legs on bed

6 Ps: pain (unrelieved and at rest), pallor, pulselessness, paresthesia, paralysis, poikilothermia

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8
Q

Causes and Risk factors of PAD

A

Risk factors:
- tobacco use
- atherosclerosis
- diabetes
- HTN
- high cholesterol
- age > 60

PAD results from arteriosclerosis that usually occurs in the arteries of the LE and is characterized by inadequate blood flow

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9
Q

Nursing process for PAD

A
  • assessment (sub, obj)
  • nursing diagnoses: ineffective tissue perfusion, activity intolerance
  • planning; overall goals w/ PAD:
    – adequate tissue perfusion, relief of pain, increased exercise tolerance, intact healthy skin, increase knowledge
  • implementation (health promotion, acute, ambulatory)
  • evaluation of the goals
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10
Q

complications, drugs/tx for PAD

A

Complications:
- nonhealing arterial ulcers and gangrene
- amputation
- wound infection, delayed healing
- tissue necrosis
- arterial ulcers over bony prominences
Drugs:
- ACE inhibitors reduce symptoms
- drugs for intermittent claudication
Treatments - want to reduce CVD risk factors
- PTA, revascularization, decrease CVD risks (diet, statins, antiplatelets, ACE inhibitors, beta-blockers), angiogenesis
- IR and catheterization, atherectomy, etc
- surgical procedures
- control BP, tobacco cessation, high A1C control, change diets

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11
Q

Clinical manifestations of PVD

A
  • pain with dangling feet and needing to elevate legs
  • exudate drainage
  • irregular sores around ankles
  • lower leg swelling
  • dependent edema

V: voluptuous pulses - warm legs
E: edema
I: irregularly shaped
N: no sharp pain
Y: yellow and brown ankles

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12
Q

Causes and Risk factors of PVD

A

Can be caused by varicose veins, chronic venous insufficiency, or venous embolism
- narrowing of veins interfering with return of blood to heart

Risk factors:
- smoking
- atherosclerosis
- DM, HTN
- high cholesterol

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13
Q

Nursing care, drug/tx for PVD

A

Nursing care: help with blood flow back to heart
- keep hydrated
- movement every 1-2 hours, prevent sitting
- elevate legs for 20 mins ev 4-5hrs
- compression stockings
- assess HR, BP, pulses

Drugs/tx:
- exercise
- dietary changes
- do not cross legs
- compression stockings
- anticoags if needed

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14
Q

VTE - what is it, what does it include?

A

venous thromboembolism; includes DVT and pulmonary embolism
- clot formation occurs when localized platelet aggregation and fibrin entrap RBCs, WBCs, and more platelets
- deep veins of arms or legs, pelvis, vena cava, and pulmonary system

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15
Q

Clinical manifestations of VTE

A

superficial vein thrombosis:
- most common
- palpable, firm, cordlike vein
- itchy, painful, red and warm
- mild fever, leukocytosis

VTE including DVT and PE:
- unilateral leg edema
- pain
- erythema
- chronic venous insufficiency
- embolism of thrombotic fragments
- warmth, redness
- coughing up blood, chest pain

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16
Q

Causes and risk factors of VTE

A
  • venous stasis: dysfunctional valves, inactive extremity muscles, at risk population
  • endothelial damage
  • hypercoagulability of blood

risk factors:
- sedentary lifestyle
- obesity
- DM
- atherosclerosis

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17
Q

Nursing care, drugs/tx for VTE

A

Nursing care:
- pain relief
- decrease edema
- no skin ulcerations, bleeding complication
- no PE
Three VTE measures:
- early and progressive mobilization
- graduated compression stockings
- intermittent pneumatic compression devices to increase venous return
Drug therapy: anticoagulants
- vitamin K antagonists
- thrombin inhibitors
- factor Xa inhibitors

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18
Q

Raynaud’s Phenomenon

A

episodic, vasospastic disorder of small cutaneous arteries
- fingers and toes most commonly affected
- more common in women (15-40 y/o)

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19
Q

Clinical manifestations of Raynaud’s Phenomenon

A

in stress or cold: fingers and toes turn white-blue-red episodes
- primary: disease occur in any stress or cold
- secondary: phenomenon underlying connective tissue diagnosis (lupus, scleroderma) that damages the arteries

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20
Q

Causes, diagnosis, and treatment for Raynaud’s Phenomenon

A

Pathogenesis: abnormalities in vascular, intravascular, and neuronal mechanisms that cause vasodilation
Dx: ANA titer, clinical symptoms
Tx: vasodilators or sympathectomy in extreme cases

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21
Q

Teaching for Raynaud’s Phenomenon

A

avoid the cold, dress warmly, decrease caffeine intake, manage stress levels, stop smoking

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22
Q

Nervous System Assessment

A
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23
Q

Acute head injury: concussion - clinical manifestations

A
  • headache
  • confusion
  • dizziness
  • sometimes loss of consciousness
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24
Q

Acute head injury: concussion - causes

A
  • mild TBI caused by jolt to head
  • immediate medical eval is crucial
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25
Acute head injury: meningitis - clinical manifestations and causes Signs?
- fever - headache - stiff neck - altered mental status - brudzinski and kernig's signs Causes: - inflammation of the membranes surrounding the brain and spinal cord, usually caused by infection
26
acute head injury: brain tumor - clinical manifestations and causes
Manifestations: - headaches - seizures - cognitive or personality changes Causes: - benign or malignant tumor, affecting brain function by causing pressure or invading brain tissue
27
Headaches - causes
tension, migraines, underlying conditions
28
Seizure disorders - clinical manifestations and causes
Clinical manifestations: focal or generalized, vary based on seizure type Causes: uncontrolled electrical activity in the brain leading to seizures
29
Parkinson's disease - clinical manifestations and causes
Clinical manifestations: - tremors - stiffness - slowness of movement Causes: progressive neurological disorder that affects movement
30
Multiple sclerosis - clinical manifestations and causes
Manifestations: - fatigue - muscle weakness - coordination problems Chronic illness that affects the brain and spinal cord
31
Huntington's disease - clinical manifestations and causes
Manifestations: - cognitive decline - mood swings - involuntary movements; chorea - hallucinations - speech difficulties - behavioral and personality changes Hereditary disorder leading to the progressive breakdown of nerve cells in the brain
32
ALS: clinical manifestations and causes
Rapidly affecting the ability to move, speak, eat and breath Fatal motor neuron disease causing muscle weakness and atrophy
33
Delirium and dementia
Delirium is an acute fluctuating state of confusion - Dementia is a gradual decline in cognitive function due to disease or injury
34
Myasthenia Gravis: clinical manifestations
- muscle weakness and fatigue - drooping in eyelids - altered speaking - limited facial expressions - double vision which improves with one eye closed
35
Myasthenia Gravis: causes
autoimmune neuromuscular disease affecting various parts of the skeletal body; requires medication potential surgery
36
TIA: clinical manifestations
A transient episode of neurologic dysfunction caused by focal brain, spinal cord, or retinal ischemia but without acute infarction of brain - symptoms typically last less than 1 hours
37
TIA: causes and risk factors
Greater risk of having a stroke in future Caused by a partial blockage caused by focal brain, spinal cord, or retinal ischemia - without acute infarction of the brain
38
TIA: nursing care
There is no way to predict outcome; history of TIA is associated with increased risk of stroke: - 1/3 do not have another event - 1/3 have more TIAs - 1/3 progress to stroke
39
Nervous system diagnostic tests
40
Stoke: clinical manifestations r/t:
- related to location of stroke; neural tissue destruction is basis for neurologic dysfunction - affects many body functions (r/t artery involved, area of brain supplies, time of onset/length of ischemia)
41
Stroke - clinical manifestations: motor function
- most obvious effect of stroke - impairment of: -- mobility -- respiratory function -- swallowing and speech -- gag reflex (worry about aspiration) -- self-care abilities characteristic motor deficits: - loss of skilled voluntary movement (akinesia) - impairment of integration of movements - changes in muscle tone - altered reflexes (changes from hyporeflexia to hyperreflexia) - can have initial period of flaccidity - spasticity of muscles follows flaccid stage
42
Stroke: clinical manifestations - communication
Aphasia: occurs when stroke damages the dominant hemisphere of brain and affects language - receptive (wernicke's): loss of comprehension - expressive (Broca's): loss of production of language - global: total inability to communicate Dysphasia: refers to impaired ability to communicate - used interchangeably with aphasia - nonfluent: minimal speech activity with slow speech - fluent: speech is present but has little meaningful communication dysarthria: problem with muscular control of speech - troubles with pronunciation, articulation, phonation - does not affect meaning of communication or language comprehension
43
Stroke: clinical manifestations - affect
- may have a hard time controlling their emotions - emotional responses may be exaggerate or unpredictable - magnified by: -- depression -- changes in body image -- loss of function -- mobility and communication problems
44
Stroke: clinical manifestations - intellectual function
- both memory and judgment may be impaired because of stroke
45
Stroke: clinical manifestations - spatial perceptual alterations
- stroke on right side of brain is more likely to cause problems in spatial-perceptual orientation - incorrect perception of self and illness - unilateral neglect of affected side: homonymous hemianopsia - agnosia: don't recognize an object - apraxia: ability to carry out learned movement on commands
46
Stroke: right brain and left brain stroke
47
What is an ischemic stroke
results from inadequate blood flow to brain from partial or complete occlusion of an artery classified as thrombotic or embolic
48
What is a thrombotic stroke?
ischemic stroke classification - occurs from injury to a blood vessel wall and formation of a blood clot - results in narrowing of blood vessel; most common cause of stroke - often associated with HTN or DM Extent of stroke depends on: - rapidity of onset - size of damaged area - presence of collateral circulation
49
What is an embolic stroke?
ischemic stroke - occurs when an embolus lodges in and occludes a cerebral artery - result in infarction and edema of area supplied by involved vessel - second most common cause of stroke Manifestations: - sudden onset with severe clinical manifestations - warning signs are less common - patient usually conscious - prognosis related to amount of brain tissue deprived of blood supply - recurrence is common
50
What is a hemorrhagic stroke?
Results from bleeding into: - brain tissue itself -- intracerebral or intraparenchymal hemorrhage - subarachnoid space or ventricles
51
Hemorrhagic stroke: Intracerebral hemorrhage (what is it, causes, manifestations)
Bleeding within brain caused by rupture of a vessel - sudden onset of symptoms - progression over minutes to hours; prognosis is poor - hemorrhage occurs usually during activity Hypertension is most common cause - other causes: vascular malformation, coagulation disorders, anticoagulant drugs, trauma, brain tumors, ruptured aneurysms - extent of symptoms varied and depends on amount, location, and duration of bleeding Manifestations: because of increased ICP - neurologic deficits - headache - nausea, vomiting - decreased levels of consciousness - HTN
52
Stroke: nursing assessment: BE FAST
Balance Eyes Face Arms Speech Time
53
Stroke: nonmodifiable and modifiable risk factors
Nonmodifiable risk factors: - age: risk doubles each decade after 55 - gender: more common in men but more women die - ethnicity/race - heredity/family history Modifiable risk factors: - HTN - heart disease - DM - serum cholesterol - smoking - obesity - sleep apnea - metabolic syndrome - lack of physical exercise - poor diet - drug and alcohol use
54
Stroke: diagnostic tests
MRI or noncontrast CT scan: show size and location of lesion - distinguish between ischemic and hemorrhagic stroke other studies: - CTA or MRA - CT/MRI - cerebral angiography - digital subtraction angiography - transcranial doppler ultrasonography - lumbar puncture - LICOX system
55
Stroke - nursing management (primary assessment and comprehensive neuro exam)
primary assessment focuses on: - cardiac status - respiratory status - neurologic assessment if patient stable, obtain history secondary assessment includes a comprehensive neurologic examination: - level of consciousness - NIH stroke scale - cognition - motor abilities Comprehensive neurologic examination: - cranial nerve function - sensation - proprioception - cerebellar function - DTRs
56
Stroke: nursing care - acute care
Goals: manage airway, breathing, circulation, intracranial pressure stroke can affect all systems - need to assess all, prevention of skin breakdown, nutrition communication, sensory-perceptual problems, sensory-perceptual alterations, coping
57
Acute care: ischemic stroke
- Control fluid and electrolyte balance - manage ICP - recombinant tissue plasminogen activator (tPA): dissolves clot, must be started within 3-4.5 hours of onset of clinical signs of ischemic stroke -- patients are carefully screened -- blood tests for coagulation disorders; hx of GI bleeding, stroke, head trauma, internal bleeding
58
Stroke: nursing care - rehab
after stroke patient has stabilized for 12-24 hours: care goals shift from preserving life to lessening disability and reaching optimal function - evaluated by physiatrist - some aspects begin as soon as patient is stable interprofessional care including SLP, PT, OT, dietary, neuro
59
Stroke: nursing care - planning and goals
Goals include that patient will: - maintain stable or improved level of consciousness - attain maximum physical functioning - attain maximum self-care abilities and skills - maintain stable body functions - maximize communication abilities - maintain adequate nutrition - avoid complications of stroke - maintain effective personal and family coping
60
Stroke: nursing care - implementation (health promotion)
health promotion: - reduce incidence of stroke - focus on stroke prevention - teach how to reduce modifiable risk factors BP screening and antihypertensive therapy Anticoagulation therapy for AFib Teach early symptoms of stroke and TIA
61
Stroke: drugs and treatment
Preventative drug therapy: - antiplatelets - ASA 81 mg/day - warfarin - direct factor Xa inhibitors Drug therapy for hemorrhagic stroke: - anticoags and platelet inhibitors contra - manage HTN: oral and IV agents - seizure prophylaxis is situation specific Surgical interventions for patient with TIAs due to carotid disease: CEA, transluminal angioplasty, stenting Endovascular: stent retrievers Surgical therapy for hemorrhagic stroke: - evacuation of hematomas - AVM resection and/or radiosurgery - catheter embolization - clipping or coiling of an aneurysm
62
Pre-op, intra-op, post-op: communication
Patient interview: occurs in advance or day of surgery - obtain info regarding food and drug allergies - identify the reason the patient is having surgery and any comorbidities - identify potential risks and complications of the surgical procedure - preop: jewelry must come off, denture can go (pt sticker to identify), hearing aids kept during preop
63
Pre-op, intra-op, post-op: education
Preoperative teaching: patient has right to know what to expect and how to participate several days before surgery; know care expected after surgery - increases patient satisfaction - reduce fear, anxiety, stress - may decrease complications such as pain and vomiting - include info focused on safety, highest priority teaching points, written material - do teaching several days before surgery, priority to patient concerns - teach deep breathing, coughing, early ambulation - inform if tubes/drains/monitoring devices will be used post-op - what they are to expect with surgery-specific information
64
Possible complications with surgery
- signs of infection after surgery - anesthesia depresses the respiratory system - DVT, risk for PE -- s/s: sudden SOB, tachypneic perfusion - increased risk for bleeding: anticoags, antiplatelets, st. johns wort, garlic, ginkgo biloba, ginseng - incentive spirometer to prevent pneumonia - allergies: latex allergy (bananas and avocados), shellfish allergy (contrast dye) - anaphylactic reaction: angioedema, hives, rash, contact anesthesia - malignant hyperthermia - dehiscence
65
Pre-op, intra-op, post-op: safety
- letting the patient know that pain or lack of mobility is to be expected - 6 hours is recommended for food before surgery; minimum 2 hours for fluids, few sips of water - check that all required forms are signed and in chart - contact person, not driving yourself - insulin given even if NPO to T1DM
66
Operative areas: unrestrictive
main office, dressing rooms, main desk, areas where street clothes are permitted; receiving area for supplies and equipment
67
Operative area: semi-restrictive
areas where hat, scrubs, and designated shoe covers are worn; hallways leading into the OR suites; sterile storage areas (depending on policy) not mask or gloves
68
Operative area: restrictive
area where there are opened sterile supplies; sterile storage areas (depending on policy)
69
What is a surgical time out
- ID of patient, DOB, what procedure they are having, ask the patient - mark surgical site - stop if patient doesn't understand - happens before anesthesia given and while patient is still awake Complications that may occur: - Malignant hypertension(trending vital signs in higher range to hypertensive crisis) - Malignant hypothermia(use bear hugger or warming blanket) - Anaphylaxis
70
What is done preoperatively?
- obtain and provide baseline data, preoperative assessments - provide comfort - we must: -- identify the reason the patient is having surgery -- assess patients response to stress of surgery -- insulin to NPO DM -- think about any OTC meds - review results of pre-op diagnostic tests - identify potential risks and complications of surgical procedure -- bleeding, pneumonia -- DVT that can become PE
71
Post-op care
- Begins immediately after surgery... - PACU-post anesthesia care unit, limits transportation and gives readily access - Option respiratory assessment or vital signs taking respiratory assessment - Nursing focus is to maintain pt safety and identify actual or potential problems
72
Post-op assessment
Prevent complication, orient pt, support emotional status, tissue perfusion, output and intake(oliguria<400mL), pain control, adequate temperature(malignant hyper/hypothermia), respiratory function, encourage coughing/deep breathing(don't for certain parts of body bc inc. ICP), through HTT, infection control, vitals, elimination evaluation - A(patent airway) B(RR, breath sounds, Sp02) C(capillary refill, ECG) - TURP(do expect pink or bloody urine during surgery, compared to other surgeries) - Dehiscence: wound reopens fix with wet sterile gloves - Assess bowel sounds/flatulence to see if they are returning - Cough and breathing - Fluids stool softeners, eat a regular meal to have urge - 4-6 hrs if havent peed after removing cath pt needs to pee - Surgery inc. metabolic needs, needs glucose - Insulin IV can be used for hyperkalemia - May be giving or holding insulin during or after surgery - Problems with anesthesia really constipated or gas pains need to get it moving - Assistive devices used and pain meds if needing to wound care, PT will be hepful - Only Dr. is supposed to remove initial dressing if surgical site is soaked call the doctor Is it bleeding, is there infection(warmth/redness/purulent discharge) want bed of wound cool to touch to look clean dry and intact pink color to wound bed...same w dressing - If pt has fever and heart rate is elevated could be indicative of infection - If extremity or bone surgery assess C(circulation)M(motor)S(sensory)
73
Geriatric considerations post-op
- decreased kidney function, drugs may be lingering - can develop confusion - assess LOC: hypoglycemia, hypoxia, infection
74
Visual problems: Refractive errors
Refraction: eye's ability to bend light rays so they fall on retina; create sharp image - myopia: nearsighted - hyperopia: farsighted - presbyopia: loss of accommodation - astigmatism: visual distortion - aphakia: absence of lens Corrections: corrective glasses, contacts, laser surgical therapy, implant surgical therapy
75
Assessment of visual system
- sub; obj data - focused assessment: subjective and objective (inspections and assessing vision) - initial observation: -- color combinations; head position; covering eyes; depth perception; face and appearance - assessing functional status -- visual acuity: right eye first then left -- Snellen eye chart (legal blindness is 20/200 with correction) -- near vision difficulty or age greater than 40: Jaegar chart - extraocular muscle function (corneal light reflex, six cardinal positions for eye movement) - pupil function and intraocular pressure (PERRLA) - physical examination of structures, conjunctiva and sclera
76
Gerontologic considerations: visual impairment
- every structure of visual system changes - changes may be benign or result in severely compromised visual acuity Increased risk for vision loss: - alters ability to function, may have other deficits - societal devaluation - inadequate finances - increased fall risk - concerns with independence - dexterity and administration of eye drops or other medications
77
Retinal detachment
Emergency! separation of retina and underlying epithelium; fluid accumulation between layers Manifestations: - flashes of light - floaters - cobweb/hairnet or ring in field of vision Need surgical therapy
78
Glaucoma
Group of disorders characterized by increased IOP and subsequent optic nerve atrophy and peripheral visual field loss - 2nd leading cause of permanent blindness Patho: - Aqueous production (inflow) and aqueous reabsorption (outflow) must be balanced to maintain IOP - Outflow occurs at angle where iris meets cornea - Inflow > outflow --> increased IOP -- Increased IOP --> permanent loss of vision
79
Types of glaucoma
Primary open-angle glaucoma (POAG) Angle-closure glaucoma (ACG) Acute angle-closure glaucoma (AACG)
80
Clinical manifestations of glaucoma: POAG and AACG
POAG: - initially asymptomatic - gradual loss of peripheral vision: optic nerve damage - late or untreated: tunnel vision AACG: ocular emergency - severe, sudden pain in or around eye - N/V - colored halos, blurred vision, ocular redness
81
What is the normal intraocular pressure (IOP)?
10-21 mmHg POAG: IOP 22-32 AACG: IOP > 50
82
Cataracts
Opacity in the lens; can be in one or both eyes - altered metabolic processes in lens cause water accumulation and changes in lens fiber structure, altering transparency resulting in vision changes Manifestations: - decreased vision - abnormal color perception - glare Dx: ophthalmoscope or slit lamp No cure other than surgical removal - can have temporary nonsurgical: prescription eyewear, visual aids, increase light and change lifestyle
83
Age Related Macular Degeneration
Leading cause of irreversible central vision loss Two forms: - Dry (nonexudative): atrophy of macular cells -- more common; slow, progressive, painless loss of vision - Wet (exudative) -- more severe; abnormal blood vessels develop in or near macula -- rapid onset of vision loss; AMD-related blindness
84
Risk factors and clinical manifestations for Age Related Macular Degeneration
Risk factors: - fam hx - obesity - HTN - being white - smoking Clinical manifestations: - blurred and darkened vision - scotomas (blind spots) - metamorphopsia (vision distortion) - acute vision loss
85
Retinopathy
Microvascular damage to the retina; blurred vision; progressive loss of vision - most common with HTN or DM Diabetic retinopathy: - nonproliferative: loss of central vision - proliferative: advanced disease; severe vision loss - treatment: laser photocoagulation Hypertensive retinopathy: - treatment: lower BP to restore vision
86
UTI
Most common outpatient infection - classified by location: upper and lower -- pyelonephritis: renal parenchyma and collecting system -- cystitis: bladder -- urethritis: urethra - can be complicated or uncomplicated (underlying compromise or structural issue)
87
Lower urinary tract symptoms (LUTS): Clinical manifestations (emptying and storage)
- emptying symptoms: hesitancy, intermittency, post-void dribbling, urinary retention or incomplete emptying, dysuria - storage symptoms: urinary frequency, urgency, incontinence, nocturia, nocturnal enuresis - hematuria and/or cloudy appearance many problems produce LUTS; often confused with UTI
88
UTI: upper urinary tract symptoms
- flank pain, chills, fever Other: fatigue, anorexia, or asymptomatic
89
Older adult considerations with UTI
classic manifestations absent - nonlocalized abdominal discomfort - cognitive impairment/confusion - generalized deterioration - often afebrile
90
Diagnostic studies for UTI
- initial: dipstick for nitrates, WBCs, and leukocyte esterase - urine culture/sensitivity (clean catch urine sample) - take history (recurring UTIs, complicated UTIs, CAUTIs or HAI UTI, UTI unresponsive to empiric therapy) - imaging: ultrasound or CT scan
91
Drug therapy for UTI
Uncomplicated or initial UTI: - Bactrim - nitrofurantoin cephalexin - ampicillin, amoxicillin, cephalosporins Complicated: fluoroquinolones Fungal: fluconazole Urinary analgesic: phenazopyridine
92
Kidney stones (urinary tract calculi): what are they and risk factors
Nephrolithiasis: kidney stone disease Risk factors: - metabolic - climate - diet - genetic - lifestyle Concentration of supersaturated crystals precipitate and form stone - can reduce risk by keeping urine diluted and free flowing (drink fluids)
93
Five categories of urinary stones
- calcium oxalate - calcium phosphate - cystine - struvite - uric acid calcium stones are most common can be mixed and in various locations
94
Clinical manifestations of kidney stones
First symptom: sudden, severe pain (renal colic) - flank area, back or lower abdomen - ureter stretches, dilates, and spasms - may see N/V, "kidney stone dance", dysuria, fever, chills, moist cool skin Common obstruction sites: - ureteropelvic junction (UPJ): CVA flank pain/renal colic - ureterovesical junction (UVJ): lower abd. pain; testicular or labial pain
95
Diagnostic studies for kidney stones
- noncontrast helical (spiral) CT scan - ultrasound - UA - 24hr urine Retrieval and analysis of stones important to determine problem contributing to stone formation
96
Treatment and patient teaching with kidney stones
- adequate hydration; high intake of water (3L/day to produce 2.5 L urine/day if no CV or renal compromise) - sodium restriction - diet changes - drugs: alter pH of urine, prevent excess urinary secretion of a substance or correct primary disease Tx: some can pass; some too large and need surgical removal or scopes or broken up - type of surgery depends on location of stone - struvite stones: abx and acetohydroxamic acid; surgery
97
Urinary incontinence - what is it
Involuntary leakage of urine - more prevalent with older adults, esp women - Women: stress and urge incontinence - Men: common with BPH or prostate cancer; overflow incontinence from urinary retention
98
Urinary incontinence: Pathophysiology (DRIP)
D: delirium, dehydration, depression R: restricted mobility, renal impaction I: infection, inflammation, impaction P: polyuria, polypharmacy
99
Types of urinary incontinence
- stress - urge - overflow - reflex - incontinence after trauma or surgery - functional incontinence can have more than 1
100
Healthcare associated infections
UTIs are the most common HAI - catheter-associated UTI (CAUTI): E. coli or pseudomonas - increased length of stay, costs, mortality
101
BPH
Benign Prostatic Hyperplasia AUA uses tool to assess voiding symptoms: - not diagnostic but provides guidelines for treatment - high score = increased symptom severity
102
BPH: risk factors
- aging - obesity: increased waist circumference - lack of physical activity - high intake of red meat and animal fat - alcohol use - ED - smoking - DM - family history: first-degree relative
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BPH: clinical manifestations (irritation and obstructive)
- manifestations occur gradually -- early: bladder may initially compensate for small amounts of resistance to urine flow -- symptoms worsen as obstruction increases - Lower urinary tract symptoms (LUTS) -- irritative symptoms -- obstructive symptoms Irritative symptoms: inflammation or infection - nocturia: often first - urinary frequency - urgency - dysuria - bladder pain - incontinence Obstructive symptoms: caused by prostate enlargement, decreased diameter of urethra - decrease in caliber and force of urinary stream - difficulty initiating a stream - intermittency: starting and stopping stream several times - dribbling at end of urination
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BPH: complications
- relatively rare: -- acute urinary retention: sudden and painful inability to urinate -- need catheter insertion and surgery if severe -- bladder damage can occur - UTI - if severe: pyelonephritis, sepsis, bladder calculi - renal failure -- caused by hydronephrosis -- bladder damage
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Hemodialysis
- Requires rapid blood flow and access to a large blood vessel - Obtaining vascular access is the most difficult problems - Complications: Hypotension (change in VS), Muscle cramps, Loss of blood, concerns for fluid volume issues, hyperkalemia(need dialysis quick), hepatitis - Fluid restrictions for this pt because of fluid retention - Surgically placed has fistulas healthy that vibrate upon palpation feel thrill d/t turbulent blood flow, should hear bruit - Limb alert on someone with fistula “life line”
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Peritoneal Dialysis
- Peritoneal access is obtained by inserting a catheter through anterior abdominal wall, can be done at home, lower risk for infection - May start right away or be delayed until site healed - Aseptic technique is important to avoid peritonitis - Nutrition: need to INC protein and restrict fluids, sodium, potassium (risk of hyperkalemia)
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Type 1 DM
Autoimmune disorder - body develops antibodies against insulin and/or pancreatic beta cells that produce insulin, resulting in not enough insulin to survive - can have idiopathic diabetes - LADA: slow progressive type 1 DM in adults Requires exogenous insulin
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Clinical manifestations of Type 1 DM
3 Ps weight loss weakness fatigue DKA
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Type 2 DM
Most prevalent; many risk factors: overweight, obese, advanced age, family history - pancreas usually makes some endogenous insulin but not enough is produced and/or body does not use insulin effectively Major distinction: - presence of endogenous insulin - in type 1 DM: absence of endogenous insulin
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Clinical manifestations of Type 2 Dm
- nonspecific symptoms - fatigue - recurrent infection - recurrent vaginal yeast or candida infection - prolonged wound healing - visual problems
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Diagnostics for DM
- A1C level 6.5% or higher - Fasting plasma glucose (FPG) level > 126 mg/dL - 2-hour plasma glucose level during OGTT greater than 200 mg/dL (with glucose load of 75 g)
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Prediabetes
Impaired glucose tolerance (IGT) - OGTT—140 to 199 mg/dL Impaired fasting glucose (IFG) - Fasting glucose of 100 to 125 mg/dL May have both IGT and IFG Intermediate stage between normal glucose homeostasis and DM
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To prevent hypoglycemia, know the onset, peak and duration of insulin
Sliding scale used for rapid acting, give right before eating - Short acting/Intermediate acting is what can be mixed NRRN - NPH is cloudy, longer acting but not super long - Get lantus at night do the job of pancreas - Hypoglycemia(lethargy, cold, clammy)
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Insulin peaks
Rapid Acting: onset 10-30 mins, peak 30 min-3 hrs, duration 3-5 hrs - Ex: lispro(Humalog), aspart(Novolog), glulisine(Apidra) Short Acting: onset 30 mins-1hr, peak 2-5 hrs, duration 5-8 hrs - Ex: Regular(Humulin R, Novolin R) Intermediate Acting: onset 1.5-4 hrs, peak 4-12 hrs, duration 12-18 hrs - Ex: NPH( Humulin N, Novolin N) Long Acting: onset 0.8- 4hrs, peak not present, duration 16-24 hrs - Ex: glargine(Lantus), detemir(Levemir), degludec(Tresiba) used for basal dosing typically Inhaled Insulin: onset 12-15 mins, peak 60 mins, duration 2.5-3 hrs - Ex: Afrezza
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Rapid acting insulin
aspart, glulisine, lispro onset of action: 15 mins injected within 15 mins of meals
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Short acting insulin
- onset of action 30-60 mins - injected 30-45 mins before meal
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Intermediate-acting insulin
NPH - duration: 12-18 hours - peak: 4-12 hours - can mix with short and rapid acting - never give IV
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Long-acting insulin
basal rate - administered once or twice a day - released steadily and continuously with NO peak action - onset varies
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Sick day and diabetes
need to make sure eating or watching blood glucose because sugar can be dropping
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SIADH
- results from overproduction of ADH which leads to increased reabsorption of water into the circulation Manifestations: - low urine output - increased body weight - dyspnea - fatigue - hyponatremia: muscle cramping and headache
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DI (diabetes insipidus)
- caused by deficient production or secretion of ADH which results in fluid and electrolyte imbalances; too little ADP - dumping out really dilute urine Manifestations: - increased urine output - increased serum osmolality (hypernatremia) - polydipsia - polyuria Hypernatremia can be caused by inadequate fluid intake or fluid loss; here it is fluid loss
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Addison's: patho (primary and secondary)
Primary: - addison's disease - reduction of glucocorticoids, mineralcorticoids, androgens Secondary: - lack of pituitary ACTH - lack of glucocorticoids and androgens
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Clinical Manifestations of Addison's
- insidious onset: -- anorexia -- nausea -- progressive weakness -- fatigue -- weight loss - disease often advanced before diagnosed - abdominal pain - diarrhea - headache - orthostatic hypotension - salt craving - joint pain
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Addisonian Crisis
- acute adrenal insufficiency - insufficient or sudden, sharp decrease in hormones - life-threatening emergency Various triggers: - stress, infections, surgery - sudden withdrawal of corticosteroids - adrenal surgery - sudden pituitary gland destruction
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Addison's complications: Manifestations of glucocorticoid and mineralcorticoid deficiencies
- hypotension, tachycardia - dehydration - decreased sodium, increased potassium, increased glucose - fever, weakness, confusion - severe vomiting, diarrhea, pain - shock may cause circulatory collapse
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Breast CA
2nd most common cancer - hormonal regulation is related to breast cancer; genetic link in mutation of BRCA gene manifestations: - lump - thickening - mammography abnormality do not take BP on side of a mastectomy or lymph nodes taken out: limb alert
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Testicular CA
Patho: - most common cancer in males ages 15-34 - more common with cryptorchidism, fam hx, or anomalies - predisposing factors: orchitis, HIV, maternal exposure to exogenous estrogen, and testicular cancer of other testis Develops from 2 types of embryonic germ cells - seminoma: most common but least aggressive - nonseminomas: rare but very aggressive Non-germ cell tumors come from other testicular tissue: less than 10%
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Gardasil vaccine
HPV vaccine ages (-) to help prevent types of cancer
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Chlamydial Infections: clinical manifestations - men, women, rectal, throat
- often asymptomatic Men: - pain with urination (dysuria) or urethral discharge - rare: testicular pain or swelling Women: - mucopurulent vaginal discharge, abnormal vaginal bleeding, dysuria, pain with intercourse Rectal: - anorectal pain, discharge or bleeding, anal pruritus, tenesmus, mucus-coated stools, painful BMs Throat: asymptomatic or sore throat
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Chlamydial Infections: patient education
- all sexual contacts within 60 days should be evaluated and treated - abstain from sex for 7 days after treatment or until all partners have been treated and abstained for 7 days - high rate of recurrence of infection - must treat sexual partner(s) to avoid "ping-pong" effect: treatment, re-exposure, reinfection
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STI treatment: Chlamydia
Bacterial infection Doxycycline twice a day for 7 days Alternates: erythromycin, ofloxacin, levofloxacin
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Gonococcal Infections (gonorrhea)
2nd most common reportable STI - incidence increasing - caused by gram-negative bacteria - transmitted by exposure to sexual fluids; ejaculation not necessary - incubation period 1-4 days - prior infection does not provide immunity to subsequent reinfection
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Gonococcal Infections (gonorrhea): Clinical manifestations (rectal and oropharyngeal)
Symptoms of rectal gonorrhea: - mucopurulent rectal discharge or bleeding - pain - pruritus - tenesmus - mucus-coated stools - painful BM Symptoms of oropharyngeal gonorrhea: - few, if any symptoms - some have a sore throat
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Gonococcal Infections (gonorrhea): Complications
- men often seek treatment early due to symptoms; are less likely to develop serious complications -- epididymitis can cause infertility - women often asymptomatic; serious complications from lack of care -- infection in Bartholin's or Skene's glands -- PID can cause ectopic pregnancy, infertility, chronic pelvic pain Neonates can develop gonococcal conjunctivitis - from exposure to infected mother during delivery - can result in permanent blindness - almost all states require prophylactic treatment for newborns
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STI treatment: Gonorrhea
Bacterial infection - drug therapy often started before test results return - has developed resistance to many classes of antibiotics - first line treatment: high-dose IM ceftriaxone -- do sensitivity testing on patients who persistently test positive Patient education: - treat all sexual contacts within last 60 days; abstain from sexual contact for 7 days - return for repeat testing in 3 months
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Gender Considerations for STI: Men
- syphilis, gonorrhea more common - more likely to have symptoms of genital infection - genital infection results in fewer complications - easier to diagnose; less complex anatomy - less likely to seek care unless symptomatic
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Gender Considerations for STI: Women
- anatomy increases risk for STIs - less likely to show early signs of genital infection - trichomoniasis and herpes simplex type 2 more common - screen for, thus more likely to be diagnosed with HPV - have more frequent and serious complications related to STIs
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Genital Herpes Infection: Primary episode and stages
Primary Episode: - incubation period 2-12 days - primarily asymptomatic; if symptoms occur - follow stages: Prodromal stage: - period before lesions appear - burning, itching, tingling may occur at site of inoculation Vesicular stage: - few to multiple small, painful vesicles appear on buttocks, inner thigh, penis, scrotum, vulva, perineum, perianal region, vagina, or cervix - contain large quantities of infectious particles Ulcerative Stage: - lesions rupture and form shallow, moist ulcerations Final stage: - spontaneous crusting and epithelialization of erosions occur
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PID (key complication of? Symptoms and treatment)
key complication from either of syph, chlamydia, or gonorrhea is that they can lead to PID - infections spread to uterus, ovaries, fallopian tubes and can lead to sepsis symptoms: lower abdominal pain, menstrual irregularities, fever treat: need to give antibiotics and analgesics
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Stages of Syphillis
Primary: highly infectious; 3-6 week duration - single or multiple chancres - regional lymphadenopathy - exudate and blood from chancre are highly infectious Secondary: highly infectious; few wks after primary chancre heals - duration: 1-2 years - systemic flu-like symptoms - mucous patches in mouth, tongue, or cervix - symmetric, nonpruritic, maculopapular rash on palms and/or soles, and trunk or extremities Final stage: tertiary or late syphilis - no obvious symptoms - organ damage silently happening over years - gummas can lead to serious complications: inflammatory tumor-like response can be spread to fetus while pregnant
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STI treatment: Syphilis
Bacterial infection need early treatment with drug therapy and to eradicate syphilitic organisms - penicillin G benzathine recommended for all stages - alternate: doxycycline or tetracycline - treat all sexual contacts from preceding 90 days - reexamination and follow-up testing every 6 months for up to 2 years; repeat HIV testing
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STI treatment: HPV
Viral most common STI; can cause genital warts or lead to cancer - primary risk factor for cervical cancer - HPV typically asymptomatic; is preventable with vaccine Not curable but warts can be removed with prescription creams
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Expedited partner therapy
clinical practice of treating the sexual partners of patients diagnosed with chlamydia or gonorrhea by providing prescriptions or medications to the patient to take to his/her partner without the healthcare provider first examining the partner
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RPR
Rapid Plasma Reagin - is a syphilis screening test that measures antibodies present in the blood of individuals who have the disease
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Oliguria
less than 400 mL/day
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Anuria
less than 100 mL/day