exam 2

Question 1

distribution of cannabis

Answer 1

most THC smoked leaves brain within 30 mins but stays in blood for longer due to high affinity proteins

Question 2

metabolism and elimination in cannabis

Answer 2

metabolized in liver, can be detected in urine for up to a week

Question 3

typical THC effects

Answer 3

• euphoria
• relaxation
• increased appetite
• memory impairment
• heightened sensory experiences

high dose: anxiety, paranoia, sedation

Question 4

withdrawal of cannabis

Answer 4

irritability, anxiety, decreased appetite, stomach pain, aggression

Question 5

mechanisms of effects in brain (cannabis)

Answer 5

THC binds to cannabinoid, increases firing of postsynaptic neurons.

CB1 receptors found throughout brain in areas responsible for movement, coordination, memory

Question 6

biological predictors of cannabis use

Answer 6

• cannabis use disorder (CUD)
• medical conditions related to greater use for therapeutic purposes: HIV, cancer, chronic pain

Question 7

psychological predictors of cannabis use

Answer 7

• personality traits such as impulsivity
• learning mechanisms
• expectancies
• motives : medical, recreational

Question 8

social/cultural influences on cannabis use

Answer 8

• change in public perception
• public perception of risk/harm

Question 9

biological/health benefits

Answer 9

• therapeutic efficacy
• some effects might be due to expectancies

Question 10

negative biological/health effects

Answer 10

• smoking is bad for lungs
• edibles associated with higher acute physical effects
• smoking cannabus linked with reproductive health: low sperm, may harm developing fetus

Question 11

cognitive impairment (cannabis)

Answer 11

• low IQ
• memory deficit
• developing brain more sensitive to neurotoxic effects

Question 12

schizophrenia and psychosis in cannabis

Answer 12

• increased risk of psychosis
• not sole cause but interacts with other risk factors such as genes

Question 13

depression and anxiety in cannabis

Answer 13

• higher among daily users

Question 14

cannabis use disorder

Answer 14

• most people wont develop CUD
• debated whether cannabis is addictive

Question 15

social effects of cannabis

Answer 15

• doing embarrassing things
• problems at school and work
• risky things
• use of cannabis and alcohol: increase risk for heavier dependence, psychological symptoms, academic and social problems

Question 16

major classes of depressants

Answer 16

barbiturates: drug names end in “al”, early 1900s

benzodiazepines: 1960s, safer than barbiturates because threshold for overdose is higher, Many prescribed today, end with “am” sedatives and hypnotics

Question 17

GHB

Answer 17

date rape drug, naturally produced in small quantities in body