Exam #2 Flashcards
What is the definition of psychosis
Altered cognition, altered perception and/ or impaired ability to determine what is real
How is schizoaffective disorder disorder characterized?
Mood and thoughts are altered concurrently
When age does the first episode develop?
75% develop between ages 15-25
What are the psychotic symptoms that every diagnosed schizophrenic experience at least one of?
H, D, DS, AT
- hallucinations
- delusions
- disorganized speech
- altered thoughts
What are the risk factors for developing schizophrenia?
- genetics
- neurotransmitter imbalance
- brain structure abnormalities
- prenatal stressor
- environmental factors
What neurotransmitter is closely associated with schizophrenia symptoms?
- dopamine ( can be targeted via drug therapy for reduction of symptoms)
What are the different stages of schizophrenia?
P, A, S, M/R
- prodromal
- acute
- Stabilization
- maintenance of residual
What is the prodromal stage?
Phases of schizophrenia
- mild changes in mood or thoughts
- decreased concentration and social function
When will the symptoms manifest in the prodromal stage?
Phases of schizophrenia
1 month to 1 year before first psychotic episode
What is the acute stage?
Phases of schizophrenia
Ability to function is impaired and hospitalization is required
What is the stabilization stage?
Phases of schizophrenia
Symptoms stabilize or diminish and there is a return to baseline functioning
What is the maintence or residual stage?
Phases of schizophrenia
A new level of baseline functioning is established and positive symptoms are gone or mostly gone
What are positive symptoms of schizophrenia?
Hallucinations, delusions
- presence of something that shouldn’t be present
What are the negative symptoms of schizophrenia?
hygiene, anhedonia, BROAD affect
Absence of something that shouldn’t be present
What are cognitive symptoms of schizophrenia?
- impairment in memory, thinking, attention, judgement, problem solving capabilities
What are affective symptoms of schizophrenia?
Symptoms that impact the emotional response
Common positive symptoms?
D, WS, AP, C, IIC, PB
- delusions
- word salad, rhyming
- altered perception
- catatonic
- impaired impulse control
- poor boundaries
What are common negative symptoms?
4 A’S
- anhedonia: inability to enjoy activities
- avolition: lack of motivation
- affective blunting: reduced affect
- alogia: decreased speech
What is anosognosia?
Inability to realize that they are ill as a result of the schizophrenia
What kinds of assessments would you preform on a pt w/ schizophrenia?
- MSE / psychosocial assessment
- suicide risk
- substance abuse
- med compliance
- family response
- social support
What are common nursing diagnosis for a patient w/ schizophrenia?
- Disturbed sensory perception
- Altered thought process
- ineffective coping
- self care deficit
What would the nurse plan for the patient if they are in the acute phase of schizophrenia?
Goals are focused on saftey and stablization
What would the nurse plan for the patient if they are in the stabilization phase of schizophrenia?
Goals are focused on education and achieving an acceptable treatment regimen
What would the nurse plan for the patient if they are in the maintenance phase of schizophrenia?
Goals are focused on treatment adherence and the prevention of relapse
What are some interventions that can be used to help pt w/ schizophrenia?
S, DS, EB, MPW, UR
- set limits
- decrease stimuli
- observe for escalating behaviors
- minimize potential weapons
- use restraints
What is the first line of defense to treat schizophrenia?
Second generation antipsychotics
What is the mechanism of action of second generation antipsychotics?
Bind to dopamine receptors in the limbic system and also impact serotonin levels
What symptoms does second generation antipsychotic target?
Positive and negative
What are side effects of taking second generation antipsychotics?
wim
- weight gain
- increased mortality rate in dementia pts
- metabolic syndrome
What are sone examples of second generation antipsychotics?
C, Q, O, Z, P
- clozapine ( clozaril) * increased risk for infection
- Quetapine ( seroquel)
- olanzapine (zyprexa)
- ziprasidone ( Geodon)
- paliperidone (in Vega)
What is the second line of defense to treat schizophrenia?
First generation antipsychotics
What is the mechanism of action of first generation antipsychotics?
- works as a strong antagonist to block dopamine
What symptoms does first generation antipsychotic target?
Only positive symptoms
What are some examples of first generation antipyschotics?
H, L
Haloperidol ( Haldol)
Loxapine ( loxitane)
What are the serious side effects of taking antipsychotics?
ANAL
- anticholinergic
- neuroleptic malignant syndrome
- agranulocytosis ( associated with clozaril)
- liver impairment
What are the CM neuroleptic malignant syndrome?
- Decreased LOC
- temp over 103
- increased muscle rigidity
What is disruptive mood regulation disorder?
- severe irritability and anger in children/ adolescents
What is persistent depressive disorder?
Chronic depressed emotional state but less severe than MDD
What is premenstrual dysphoric disorder ?
Depressive symptoms one week prior to start of the menstrual cycle
What is the leading cause of disability in the US?
MDD nearly affects 17 million of the population
What are risk factor for MDD?
G, BC, H, HPAXA, I
- genetics
- biochemical
- hormonal
- hypothalamic pituitary adrenal cortical axis
- inflammation
What parts of the MSE would you see abnormalities in for a patient with a depressive disorder?
- affect ( flat or blunted)
- thought process ( decreased ability to problem solve)
- poor judgement ( indecisive or neg focused thoughts)
- mood ( depressed/ sad, anhedonia)
What is the mechanism of SSRI’s?
First line treatment of depression
Selectively block neuronal uptake of serotonin
What are the adverse effects of taking SSRI’s?
A, SD, GIU, SD
- anxiety/ agitation
- sleep disturbances
- GI upset
- sexual dysfunction
What are the severe side effects of taking SSRI’s?
- serotonin syndrome