exam 2 Flashcards
what are antipsychotics used for
psychotic disorders
schizophrenia
bipolar disorders
neuroleptic malignant syndrome
adverse reaction to antipsychotics
- CNS hyperactivity
- HTN, fever, sweating, lead pipe muscle rigidity
what class of medications cause EPS?
antipsychotics, more so in typical than atypical
EPS symptoms and treatment
- acute dystonia, tardive dyskinesia, pseudoparkinsonism, akathisia
- benztropine!!
medication that causes agranulocytosis
clozapine- atypical antipsychotic
very common side effect of antipsychotics
weight gain
what are mood stabilizers used for
bipolar disorders
gold standard for bipolar treatment
lithium
lithium patient teaching
patients needs adequate hydration & sodium
mood stabilizers that require bloodwork while using
- lithium
- divalproex sodium/valproic acid
- carbamazepine (tegretol)
medication to monitor for a rash & stevens-johnson syndrome
lamotrigine (lamictal)- anticonvulsant
major side effect of lithium
metallic taste
lithium toxicity
> 1.5 mEq/L
- n/v
- diarrhea
-ataxia
- hyperreflexia
- nystagmus
- vision changes
lithium therapeutic range
0.6-1.2 mEq/L
tegretol therapeutic range
4-12 mg/L
divlproex sodium/valproic acid therapeutic range
50-100 mcg/mL
what should patients avoid while using anticonvulsants
heavy alcohol use
first line treatment for depression
SSRIs & SNRIs
serotonin syndrome
CNS hyperactivity
- HTN
- sweating
- increased fever
- agitation
- disorientation
- myoclonus: sudden involuntary twitching
- hyperreflexia
which drug class has a risk of overdose
TCAs- antidepressant
which drug. class has risk for hypertensive crisis when eating tyramine-rich foods
MAIOs
buproprion black box warnings
- decreased seizure threshold
- risk of suicidal thoughts
typical antipsychotic MOA
blocks dopamine
atypical antipsychotic MOA
blocks dopamine & serotonin