Exam 2 Flashcards
Which stage are a majority of embryonic hormones produced
Blastocyst stage
Where is Human Chorionic Gonadotropin (hCG) produced
Trophectoderm
Function of hCG
Stimulating the gonads
What effect does the hCG have on the gonads
Positive effect
When is hCG produced in the stage of gestation
Early stage, detected in blood on day 8
Pathway of hCG
Fetus produces hCG, acts on CL to produce progesterone, helps embryonic development
What hormone does the human pregnancy detect in urine
Hormone hCG
Which hormone was the first that was used to manipulate reproductive cycles of diff species
Equine chorionic gonadotropin (eCG)
Which hormone is only found in ruminants
Interferon Tau (INFT)
IFNT works directly where
Uterine endometrium, stays within uterus
IFNT function
Blocks smooth muscle contractions from oxytocin, which blocks PGF2a
First step of embryonic development
Fertilization
Second stage of embryonic development
Fusion
Third stage of embryonic development
2-cell stage
Fourth stage of embryonic development
4-cell stage
Fifth stage of embryonic development
8-cell stage
Sixth stage of embryonic development
Morula
Seventh stage of embryonic development
Blastocyst
In the blastocyst, what does the inner cell mass become
The fetus
In the blastocyst, what does the trophectoderm become
The placenta
Endoderm of the embryo creates
The hypothalamus, PP, AP
Mesoderm of the embryo consists of which systems
Muscle, skeleton, cardiovascular, reproductive systems
Ectoderm of the embryo consists of
Skin, hair, nervous system
What does the endoderm make
Blastocoel
What does the mesoderm make
Inner cell mass
What does the ectoderm make
Trophetoderm
Gastrulation definition
When the inner cell mass cells intermingle to create the fetus
What does gastrulation result in
Formation of PP
Two different types of cells
Somatic cells and germ cells
Somatic cells consists of
All cells within the body except germ cells
Characteristics of somatic cells
Diploid, autosomes, sex chromosomes, mitosis
Germ cells consist of
Oognonia and spermatogonia
Germ cells characteristics
Haploid, originates from primordial germ cells, mitosis and meiosis
Transportation pathway of primordial cells becoming germ cells
Originates within yolk sac, migrates through and behind hind gut, into gonadal ridge
When the primordial cells reach the gonadal ridge, what occurs
Formation of primary sex cords
What happens when primordial germ cells undergo mitosis in the gonadal ridge
Increase germ cells and forms primary sex cords
When the primary sex cords are produced, what occurs next?
Gonadal ridge is sealed off by tunica albuginia
What gender is paramesonephros (mullerian duct)
Female
What gender is mesonephros (wolfian duct)
Male
Indifferent gonads contains both
Mullerian ducts and wolfian ducts
The mullerian duct becomes
Oviduct
The wolfian duct becomes
Vas deferens and epididymis
What happens to indifferent gonads when changes occur
Where one portion of the tract develops/regress for male/female
Alfred jost’s experiment
Consisted of removing gonads of adult rabbis
Why is the y chromosome important
Testes determining factor
All oocytes carry x chromosome, but where does the y chromosome come from
Sperm cells determine the sex of their offspring with the chromosome
Where does the external genitalia develop from
Ectoderm
What regulates external genitalia
Sex steroids
External genitalia also has
An indifferent state
Two types of external phenotypes
Sexual dimorphism (characteristics), sex steroids on brain (behavior)
Alpha-fetoprotein only binds to what hormone
Estrogen
What happens when alpha-fetoprotein binds to estrogen
Cant pass through blood-brain barrier, testosterone converts to estrogen
What happens when alpha-fetoprotein and estrogen can’t pass through blood-brain barrier?
Becomes blocked from brain and allows surge & tonic to develop
First step of reproductive cycle
Puberty
Second step of reproductive cycle
Breeding seasons
Third step of reproductive cycles
Gestation/lactation
Fourth stage of reproductive cycles
Senescence
Prepuberty in females
Infrequent GnRH pulses, decreased follicle growth
Puberty in females
Estrogen feedback established, follicle growth, LH surge in place
Factors that impact puberty timing in females
Genetics, body weight, environment, stress, social factors
What is the estrus cycle
Observation of sexual receptivity
The estrus cycle has a specific what between species
Specific characteristic length
Estrus cycle sequence of events
Physiological, behavioral, sexual receptivity vs no sexual receptivity, on the ovary, hormonal
Which squence of events for the estrus cycles show an increase in estrogen
Behavioral
What is the hormonal sequence of events of the estrus cycle based on
What’s occuring on the ovary
What does anestrus mean
Without cyclicity
Which animals are considered anestrus
Challenged, stressed, malnutrition, pregnant
Ways to classify parts of the estrus cycle
Ovarian structures, hormonal profiles, occurrence of estrus, ovulation
What happens during follicular phase
Growth of follicles
What is the dominant structure and hormone in the follicular phase
Preovulatory follicle, estrogen
When does the follicular phase start
When the CL regresses
When does the follicular phase end
Ovulation
Types of estrus during the follicular phase
Proestrus and estrus
Proestrus
Increase in estrogen (increase in follicles), decrease in progesterone (regressed CL)
Estrus
Peak estrogen concentrations, influences LH and FSH surges
What happens during the luteal phase
Growth of CL
Dominant structure and hormone of luteal phase
CL, progesterone
When does the luteal phase begin
Ovulation
When does the luteal phase end
CL regression
Types of estrus during luteal phase
Metaestrus, diestrus
Metaestrus occurs when
LH and estrogen are low, but progesterone is high
Diestrus occurs when
Estrogen is low, highest concentration of progesterone
Four types of hormonal profiles in order
Proestrus, estrus, metaestrus, diestrus
(Pigs Eat Many Donuts)
Polyestrus definition
Displays estrus throughout the year
Seasonally polyestrus definition
Displays more than one estrus cycle during a specific time of the year
Monoestrus definition
Displays estrus once a year
Animal that doesnt have a estrus cycle
Rabbits
Spontaneous ovulator definition
Ovulates with a regular frequency and doesn’t;t require copulation
Reflux (induced ovulator) definition
Ovulation occurs after stimulation of vagina and/or cervix
What species is the menstrual cycle in
Primates
What happens during the menstrual cycle
Physical sloughing of the endometrial lining
What kind of ovulation does the menstrual cycle have
Silent ovulation
First event of the menstrual cycle
Menstruation
Second event of the menstrual cycle
Follicular growth
Third event of the menstrual cycle
Ovulation
Fourth event of the menstrual cycle
Luteinization
Fifth event of the menstrual cycle
Endometrial growth
Sixth event of the menstrual cycle
Luteolysis
Outermost layer of the oocyte
Zona pellucida
Function of zona pellucida
Provides protection and assists in fertilization
Surface layer of the oocyte
Vitelline membrane
Vitelline membrane function
Contains the goodies
Space between the zona pellucida and the vitelline membrane
Perivitelline space
Perivitelline space function
Movement of vitelline membrane
Cytoplasm of the oocyte function
Contains goodies for survival
Germinal vesicle of the oocyte function
Contains genetic information
What cells surround the oocyte
Cumulus granulosa cells
Cumulus granulosa cells function
Helps maintain oocyte
What inhibits primary oocytes from continuing further in meiosis
Cumulus granulosa cells
Oogenesis definition
Formation and development of ovum
Oogonium definition
Primordial cell develops into oocyte to become oogonia from mitosis in primary sex coords
What stage do primary oocytes freeze
Meiosis 1
What occurs during meiosis 1
Many oocytes die and degrade
Granulosa cells function
Produces estrogen, considered nurse cells for oocyte
Thecal cells function
Produces testosterone
Follicular fluid function
Supports follicle growth, aids in oocyte development, mediates granulosa cell functions
Granulosa cells are responsive to which hormone
FSH
Thecal cells are responsive to which hormone
LH
Granulosa cells form from the
Cortex
Thecal cells form from the
Stroma
Three stages of folliculogenesis
Recruitment, selection, dominance
Last stage of folliculogenesis
Preovulatory follicle