Exam 1 Flashcards
Most important reproductive organ
Hypothalamus & pituitary
Female two centers of the hypothalamus
Surge and tonic
Male center of the hypothalamus
Tonic
What type of cell does the hypothalamus have
Neurosecretory cells
Hypothalamus function
Produces neurohormones and transmits information
What does the hypothalamus produce while releasing hormones
Pulses
If a hormone frequency is low, where is it considered from
Tonic center
If hormone frequency is high, where is the location
Surge
How does the hypothalamus connect to posterior pituitary
Directly through neurons
How is the pituitary gland connected to the hypothalamus
By the infundibular stalk
What tissue is the posterior pituitary composed of
Neural tissue
How does the hypothalamus connect to the anterior pituitary
Indirectly by the primary portal plexus
How is the anterior pituitary connected to the hypothalamus
By the infundibular stalk
What tissue is the anterior pituitary composed of
Granular tissue
Anterior pituitary function
Hormone storage and synthesis
Functions of female repro system
Hormone and gamete production, gamete transport, fertilization, growth/development of offspring, parturition
Why is the ovary a primary organ
Produces gametes
Function of the ovary
Gamete production and secrets hormones
First stage of follicle development
Primordial follicle
What type of cell surrounds the primordial follicle
Flattened granulosa cells
Second stage of follicle development
Primary follicle
Third stage of follicle development
Secondary follicle
Fourth stage of follicle development
Tertiary follicle
Fifth stage of follicle development
Antral follicle
First stage of ovarian structures
Corpus hemorrhagicum
Second stage of ovarian structures
Corpus luteum
Third stage of ovarian structure
Corpus albicans
Type of cell that surrounds oocyte in primary follicle
Cubodial granulosa cells
What type of cell is the secondary follicle composed of
Follicular cells
Formation of what type of cells in secondary follicle
Thecal and granulosa cells
What stage does the antrum form
Fourth stage (tertiary follicle)
Which stage of a follicle contains granulosa and thecal layers
Tertiary follicle (4th)
Which follicle stage contains a secondary oocyte
Antral follicle
Which follicle stage can rupture and ovulate
Antral follicle
Which follicle stage is first stage that is noticable
Tertiary follicle
Which ovarian structure is cumulus oocyte complex
Corpus hemorrhagicum
Which ovarian structure is a newly ruptured follicle that has ovulated
Corpus hemorrhagicum
Job of specialized granulosa cells (cumulus cells)
Ensures the oocyte remains healthy
Which ovarian structure contains specialized granulosa cells
Corpus hemorrhagicum
Which ovarian structure contains endocrine
Corpus luteum
Which ovarian structure produces progesterone
Corpus luteum
Which ovarian structure establishes and maintains pregnancy
Corpus luteum
Which ovarian structure is the regressed form of corpus luteum
Corpus albicans
Which ovarian structure is scar tissue
Corpus albicans
First layer of the female tube system
Lumen
Second layer of the female tube system
Mucosa
Third layer of the female tube system
Submucosa
Fourth layer of the female tube system
Muscularis
Fifth layer of the female tube system
Serosa
Sixth layer of the female tube system
Broad ligament
What occurs in the lumen of the female tube system
Gametes transported if the fetus is developed
Function of the mucosa layer of the female tube system
Provides nutrients to the embry
Which layer of the female tube system contains a lymphatic and blood system
Submucosa
Which layer of the female tube system provides nutrients to other layers
Submucosa
Which layer of the female tube system contains two muscle layers
Muscularis
The two muscle layers on the 4th layer of the female tube system
Longitudinal and circular
Layer of the female tube system that is a protective layer
Serosa
Layer of the female tube system that supports the tract for it to remain in place
Broad ligament
Which layer of the tube system contains 3 sections (mesovarium, mesosalphinx, mesometrium)
Broad ligament
The mesovarium of the broad ligament is around
The ovary
The mesosalphinx of the broad ligament is around
The oviduct
The mesometrium of the broad ligament is around
The uterus
Three structures of the oviduct
Infundibulum, ampulla, isthmus
Infundibulum function
Helps catch cumulus oocyte when released
Isthmus function
Supports sperm cells
Ampulla function
Moves oocyte to fertilization and provides secretion
Site of fertilization in female
Ampullary isthmic junction
Function of the oviduct
Cilia transportation & secrets substances for pH and nutrients
Three layers of the uterus
Perimetrium, miometrium, endometrium
Function of the endometrium of the uterus
Supplies nutrients to embryo
Three types of cervix
Annular rings, interdigitating pads, longitudinal folds
The cervix is composed of what cells
Secretor and ciliated cells
Functions of the cervix
Physical and chemical barrier & movement of sperm (potentially store)
What cell does the vagina contain
Squamous epithelial cells
Functions of the vagina
Chemical barrier, sperm function, copulatory organ
Primary organ of the male tract
Testicles
Why is the testicles outside of the body cavity
Temperature must be cooler than body temperature to produce sperm
Where does the testicles originally develop
By the kidney
Where do the testicles descend
Through the inguinal canal, into scrotal pouch
What causes the testes to descend
Gubernaculum
Four organs that help regulate temperature of the testes
Scrotal skin, cremaster muscle, tunica dartos, pampiniform plexus
How does the scrotal skin help with temperature regulation
Contains sweat glands for evaporative cooling
How does the cremaster muscle help regulate temperature of the testes
Pulls testes closer to body/drop testes away from body
What type of contraction is the cremaster muscle
Short-term
How does the tunica dartos help with testes temperature regulation
Contacts/relaxes based on environmental conditions
What type of contraction is the tunica dartos
Long-term
How does the pampiniform plexus help with testes temperature regulation
Cools the blood entering the testes
Four structures of the testes
Tunica albuginia, seminiferous tubules, rete testis, efferent ductules
Tunica albuginia function of testes
Allows testes to slide back and forth in scrotum pouch
Which testes structure is where sperm cells are produced
Seminiferous tubules
Function of testes
Production of gametes & secrets hormones
Seminiferous tubules function
Sperm cell production & sperm movement
Function of leydig cells
Produces testosterone
Function of basement membrane
Support
Sertoli cell function
Aids in spermatogenesis
Development of sperm cells along sertoli cells
Spermatogonia -> spermatocyte -> spermatid -> spermatozoa
Movement of sperm cells
Seminiferous tubules -> rete testis -> efferent ducts -> caput epididymis -> corpus epididymis -> cauda epididymis -> vas deferens
How are sperm cells carried to the caput epididymis
Fluids secreted by efferent ducts
Function of caput epipdidmys
Concentrate sperm cell numbers by absorption of fluid
Where do sperm cells gain fertility
Corpus epididymis
Where is the cytoplasmic droplet removed
Corpus epididymis
Cauda epididymis function
Sperm cell storage
Ampulla of males function
Muscle contractions, storage of sperm short-term, increase sperm concentration (false mounts)
Three accessory glands of the male
Seminal vesicles, prostate gland, bulbourethral gland
Seminal vesicles function
Helps prepare sperm to enter female, provides nutrients, flushes out urine, production of seminal plasma
Prostate gland function
Produces proteins & components to seminal plasma
Bulbourethral gland function
Produces gel fraction
Which two muscles propels sperm into female tract
Ischiocavernosus and bulbospongiosus
What is the s shaped structure in males
Sigmoid flexure
Fibroelastic pene
Rigid in non-erect state, straightens when increase in BP
Vascular pene
Filled with blood, higher rate of BP, no S
Afferent pathway
Stimulus to processing center
Efferent pathway
Processing center to response
Neurocrine secretion
Neurons produces hormones, travels down axon, released from terminal ending, into blood system
Paracrine secretion
Stimulation of different cells next to each other
Autocrine secretion
Stimulation of same cells next to each other
Juxtacrine
Stimulation to adjacent cells through cell junctions
Steps of studying hormones
Albation, replacement, isolate and purify, assay changes in concentrations
First endrocrinology experiment
Berthold’s experiment; is testes responsible for male characteristics
Bioassay measure
Take one object, inject it, turns into something new
Radioummunoassay measure
Looking for amount of hormone in the body
ELISA measure
Uses chemical reaction as color change
Steroids characteristics
Small, hydrophobic/lipohilic, travels in blood w/ carrier, diffuses through cell membrane, receptor 2 locations
Pathway of cholesterol to progesterone
27 carbon cholesterol -> 3 steps pregnenolone -> progesterone
Which enzyme for 27 carbon cholesterol -> 27 carbon pregnenolone
Enzyme P450scc
Which enzyme for 21 carbon pregnenolone -> 21 carbon progesterone
Enzyme 3bHSD
Which enzyme for 21 carbon progesterone -> 19 carbon testosterone
Multiple pathways
Which enzyme 19 carbon testosterone -> 18 carbon estradiol
Aromatase
Non-steroids characteristics
Large, hydrophilic, receptors on plasma membrane, needs second messenger
“Lock and key” hormone action
Specific hormone to a specific receptor
The effectiveness of a hormone depends on
The number of receptors and the affinity of hormone
Agonist hormone action
Acts like a hormone with positive response
Antagonist hormone action
Acts like a hormone but has a negative response
Oxytocin locations
Produced in hypothalamus, released and stored in PP
Oxytocin function
Promotes smooth muscle contractions
GnRH locations
Produced, stored, and released from hypothalamus
FSH locations
Produced and stored in AP
Where does FSH travel and target
Ovary or testes
What does FSH do in females
Stimulates follicle growth and E2 production
What does FSH do in males
Supports sertoli cell function, E2 production
LH locations
Produced and stored in AP
Where does LH travel and target
Ovary and testes
What does LH do to females
Stimulates ovulation, produces progesterone
What does LH do in males
Stimulates leydig to make testosterone
What cells produces testosterone
Leydig (testes), theca (follicle)
Testosterone action in males
Promotes spermatogenesis, promotes E2 secretion of accessory sex glands
Testosterone action in female
E2
Estrogen is produced by
Sertoli cells (testes), granulosa cells (follicle), placenta
What is progesterone produced by
CL, placenta
Which hormone is required for pregnancy
Progesterone
PGF2a is produced by
The tube system
Function of PGF2a
Promotes SM contractions, kills CL, ovulation
Pathway of PGF2a if pregnant
CL produces progesterone
Pathway of PGF2a if not pregnant
Releases FGF2a -> kills CL, progesterone goes away, follicles develop
PGE2 is produced by
Tube system
Actions of PGE2 in pregnancy
Stimulates pregnancy
PGE2 pathway if not pregnant
Conversion to PGF2a -> kills CL, progesterone goes away, follicles develop