Exam 2 Flashcards
Shape of Rods
large and cylindrical
Shape of cones
small and tapered
Distribution of Rods and Cones on Retina
Fovea consists soley of cones
Peripheral retina has both rods and cones
More rods that cones in periphery
Photopigment of Rods
Rods contain rhodopsin
Rhodopsin mediates dim light vision and thus is extremely sensitive to light.
Rhodopsin is a G-protein coupled receptor, and is the most abundant protein in the rod cells found in the retina (Figure 1). It functions as the primary photoreceptor molecule of vision,
Photopigments of Cones
Cones contain different forms of iodopsins
Specialization of Rods
Rods specialized for motion, dim light
Specialization of Cones
Cones specialized for color, detail, and bright light
Opsins
light-sensitive GPCRs found in photoreceptor cells on the retina
Opsins convert photons of light into an electrochemical signal through the process called phototransduction
Phototransduction
The process of the opsins converting photons of light into an electrochemical signal
What neurotransmitter does rods release in darkness?
rods release glutamate when its dark
What happens when opsins are struck by light?
Opsins including rhodopsin and iodopsins change shape and cause a biochemical cascade that closes the Na+ ion channel.
By closing this Na+ channel, Na+ ions can no longer enter the cell. This causes the cell to hyperpolarize (become more negative). This inhibits action potentials as the potential membrane becomes too negative and is below the excitation threshold. This causes the action potentials from the rods to stop.
When the rods can no longer send action potentials, less glutamate is released.
As a result, the next cells in the neural chain (bipolar cells) lose their inhibition and become active, sending signals about light to the brain.
At what wavelength (nm) do Rod pigment absorb the best?
500 nm
What are the three kinds of cones?
Small Cones (S) - 419 nm (dark blue)
Medium Cones (M)- 531 nm (light greenish-yellow)
Large Cones (L) - 558 nm (yellow)
Relative Abundance of Long, Medium, and Short wavelength cones
Long and medium wavelength cones are more abundant that short wavelength cones.
Number of Rods in Retina
120 million rods