Exam 2 Flashcards
Which of the following is NOT an effector?
a. the brain
The neurotransmitter responsible for translating action potentials into mechanical actions at muscles is
c. acetylcholine.
Alpha motor neurons in the spinal cord communicate with muscle fibers by releasing acetylcholine, which influences muscle activity by
b. directly causing muscle contractions.
The primary interaction of muscles and the nervous system involves the alpha motor neurons, which originate in the _______, exit through the _______, and terminate in the muscles
d. spinal cord; ventral root
A laboratory dog has had surgery to separate the spinal components of its motor system from the cortical and subcortical components. Which of the following best describes the motor abilities of this animal?
c. The dog demonstrates reflexive withdrawal of its foot in response to sudden stimulation.
When a voluntary movement such as contracting one’s right biceps is generated, what other signals, if any, must accompany this command?
a. A signal to antagonist muscles, such as the right triceps, to relax.
Hemiplegia is the
a. paralysis of the side of the body that is contralateral to the injured brain region.
Loss of blood flow in the _______ is the most common cause of hemiplegia
c. middle cerebral artery
The loss of a motor skill that cannot be attributed to hemiplegia, muscle weakness, sensory deficits, or motivation is called
c. apraxia.
After suffering a focal brain injury, a patient has great difficulty in pantomiming particular motor actions such as turning a key in a lock. Because other problems like hemiplegia, muscle weakness, sensory deficits, and lack of motivation have been ruled out, your diagnosis would be
b. apraxia.
Which of the following is NOT a part of the basal ganglia?
b. the claustrum
Lesions to this region of the cerebellum lead to postural instability and difficulty in keeping one’s eyes fixed on a visual object despite head or body movements
b. the vestibulocerebellum
Corticospinal fibers originate primarily in the
d. primary motor cortex.
The term decussation refers to
c. the crossing of nerve fibers from one side of the body to the other.
The excitatory command to contract the biceps muscle of the arm is normally accompanied by an inhibitory command to relax the antagonist triceps muscle. If this inhibitory signal failed to occur,
a. the passive stretching of the triceps would trigger a stretch reflex that would return the arm to its original position.
Neurons in each half of the cerebellum synapse on _______ targets in the thalamus and other subcortical structures, and therefore regulate the effectors on the _______ side of the body.
c. contralateral; ipsilateral
Single-cell recording studies have indicated that the _______ may be especially important in the control of internally guided motor sequences, whereas the _______ may be especially important in the control of externally guided motor sequences.
a. supplementary motor cortex; premotor cortex
The pyramidal motor tract carries signals from the motor cortex of each cerebral hemisphere to _______ side(s) of the spinal cord, whereas the extrapyramidal motor tracts carry signals from various subcortical structures to _______ side(s) of the spinal cord.
c. the contralateral; both the ipsilateral and contralateral
Lesions to the pyramidal motor tract would produce difficulty in moving effectors on which side of the body?
a. the contralateral side
One major difference between the pyramidal and the extrapyramidal motor tracts is their points of origin. The pyramidal tracts carry messages from _______ to the spinal cord, whereas the extrapyramidal tracts carry messages from _______ to the spinal cord.
a. cortical structures; subcortical structures
Simple reflexive motor responses to external stimuli rely primarily on the function of the _______, whereas motor behaviors that are only minimally dependent on such external cues rely primarily on the function of the _______.
c. spinal cord; motor cortex
Sherrington (1947) surgically disconnected spinal motor neurons from cortical and subcortical motor centers in laboratory animals. Which of the following statements is true about the subsequent motor behavior of these animals?
b. Reflexive responses were intact, but complex voluntary movements were disrupted.
Neurons in the spinal cord that can mediate sequences of motor actions even in the absence of external sensory feedback signals are called
b. central pattern generators.
Which of the following types of motor behavior probably relies most on the function of a central pattern generator?
a. walking
Studies of deafferentation and its effect on movement control in humans and other species demonstrate that
a. movement depends on internal mental representations of the consequences of motor commands.
The concept of endpoint control refers to the observation that voluntary muscle events
b. are programmed to result in the displacement of an effector based on its desired final location.
Single-cell recording studies of the motor control of reaching movements have demonstrated that neurons in the motor cortex are selectively active based on the
b. direction in which a reaching movement is generated.
Using single-cell recording, a researcher isolates a neuron in the motor cortex of a monkey that is extremely active when the monkey moves its arm from left to right. In subsequent trials, the animal is required to move its arm from the starting to the ending locations diagrammed here.
b. A and B
arrows moving diagonally from left to right
With regard to motor cortex, a population vector is the
c. total number of neurons that are tuned to the same preferred direction.
Which of the following statements best describes the population vector associated with a reaching movement from left to right?
d. The population vector shifts from left to right before the arm begins to move.
The fact that the population vector recorded in the motor cortex precedes the corresponding reaching movement indicates that motor cortex activity
a. is primarily involved in the planning of movement.
When you first learn how to execute the complex motor sequence that comprises a slam dunk in basketball, a circuit including the _______ is active. After much practice, once you have learned the sequence well, a second circuit involving the _______ is active.
b. lateral premotor area; supplementary motor area
The _______ seem(s) particularly important in the control and planning of complex motor sequences as opposed to simple movements.
c. motor cortex regions in the prefrontal lobes
In the period of time immediately following focal brain injury to the supplementary motor cortex, patients may reach out and grasp objects with the affected arm when they have not been asked to do so, or even when they have been explicitly told not to do so. This is an example o
d. alien hand syndrome.
In the days following her stroke, Patient E cannot refrain from reaching out and grasping nearby objects even when she has been asked not to do so. This syndrome probably is the result of the abnormal dominance of the __________ loop.
c. medial supplementary motor area
Franz and colleagues (1996) asked a patient who had had his corpus callosum surgically severed to draw figures like the ones here, each simultaneously with a different hand. Compared to neurologically intact control participants, they found that this patient
a. was better at producing movements simultaneously with both hands, even when they differed in direction.
Chapin’s early work on a brain-machine interface (BMI) in rats used an online population vector that matched the _______ of the rats’ movement.
b. force
Once a BMI takes on the ability to reward a rat that was previously rewarded by pressing a lever, how will the rat’s lever-pressing rate change?
d. Lever-pressing will eventually stop.
Which of the following sets of elements is sufficient to produce an effective brain-machine interface?
c. an electrode array to record neural activity, a prosthetic limb, and computer software that can interpret intended actions from neural activity
One limitation of most BMI systems is that they
b. use only visual feedback and not somatosensory feedback.
Parkinson’s disease results from cell death in the _______, which is a part of the _______.
b. substantia nigra; basal ganglia
A patient has damage to the basal ganglia, particularly within the striatum, and demonstrates both chorea and hyperkinesia. What is your diagnosis?
b. Huntington’s disease
What disorder is characterized by a loss of dopaminergic fibers in the substantia nigra, which results in deficits in initiating voluntary movements, bradykinesia, and the progressive emergence of a resting tremor?
b. Parkinson’s disease
Hyperkinesia is to _______ as hypokinesia is to _______.
b. Huntington’s disease; Parkinson’s disease
One proposed role of dopamine in the context of motor learning via the basal ganglia is that dopamine release
c. in the basal ganglia results in a combination of stimulatory and inhibitory influences that reinforces particular motor actions.
Which of the following is NOT an accurate description of a process related to basal ganglia influence/striatal disinhibition?
d. Inhibition of the internal segment of the globus pallidus dampens cortical activity to decrease motor output.
Keele’s work with people with Parkinson’s disease suggests that they may have difficulties in which of the following cognitive operations?
d. set shifting
One reason that lesions to the cerebellum disrupt the eye blink conditioning response is because
b. this structure is involved in timing the activation of different effectors involved in a learned motor sequence.
Which of the following would demonstrate the finding that some aspects of motor learning are independent of the specific effectors used to perform an action?
d. One’s signature looks very similar regardless of whether one uses the left or the right hand to produce it.
Using transgenic mice, Wagner et al.’s 2017 study provided which of the following pieces of evidence that the cerebellum is involved with learning and predictive processes?
c. Not only did the activity of certain cerebellar cells correspond with certain motor activity, but the activity of some cerebellar cells reflected trial outcomes
Kawai et al.’s 2015 study used rats to explore how lesions of the motor cortex impact the ability to learn and perform motor sequences. What results regarding the motor cortex did this study yield?
c. Once a new motor sequence had been learned, the cerebellum was sufficient to produce that motor sequence, even without motor cortex input.
The supplementary motor area (SMA) is particularly active during externally guided movements.
False
With time, people who experience a hemiplegia typically experience a full recovery.
False
A diagnosis of apraxia is mainly exclusionary: a person is said to have apraxia if he or she has a coordination problem that can’t be linked to a deficit in controlling the muscles themselves.
True
Single axons of the corticospinal tract can extend for more than one meter.
True
Although simple reflexes can occur without sensory input, the generation of rhythmic walking movements requires sensory feedback from the environment.
False
In performing a sequence of complex actions, such as playing the piano, each movement is planned primarily in relation to the immediately preceding and subsequent movements.
False
Before a movement is initiated, the population vector in the motor cortex has already shifted in the direction of the planned movement
True
Activity in the premotor cortex reflects not only the trajectory of a movement but also the context in which the movement occurs
True
________ is the process of acquiring new information, whereas ________ is the trace that results from this process and can be revealed at a later time.
c. Learning; memory
________ refers to the processing of incoming information to be stored.
c. Encoding
The encoding of information to be stored involves two stages: ________, in which inputs in sensory buffers and sensory analysis stages are registered, and then ________, in which a stronger representation for storage is created.
d. acquisition; consolidation
The result of acquisition and consolidation is to the process involved in accessing memory traces as __________ is to __________.
d. storage; retrieval
Which brain structure is located in the medial temporal lobe and is of particular importance in the formation of new long-term memories?
c. the hippocampus
Which of the following is NOT an area of cortex in the medial temporal lobe that interacts with the hippocampus in the formation of new long-term memories?
a. cingulate
Deficits in memory as a function of brain damage, disease, or psychological trauma are known collectively as
d. amnesia.
Which of the following statements is true of the kind of amnesia demonstrated by people with bilateral hippocampal damage (like patients H.M. and R.B.) or people with diencephalon injury (like people with Korsakoff’s syndrome)?
b. They can still learn new skills, such as the serial reaction time task, after the injury.
A 1957 study of patients who had undergone removal of the medial temporal lobe for the treatment of epilepsy suggested that
d. profound amnesia is associated only with bilateral medial temporal lobe removal.
Which of the following would be the most difficult for the famous patient H.M. and other patients with medial temporal lobe removal?
c. learning the words for numbers in a foreign language
Your favorite cartoon character has been struck over the head and can no longer remember his name or where he lives. This is an example of
d. retrograde amnesia.
Decreased oxygenation and cell death is to ____________ as beta-amyloid proteins negatively affecting synapse formation and neuroplasticity is to ____________.
c. vascular dementia; Alzheimer’s disease
You diagnose two different patients, each with a form of dementia. Patient 1 has a neurogenerative disease; Patient 2 does NOT have a neurogenerative disease. Which of the following summarizes the two patient reports?
d. Patient 1: Alzheimer’s disease, areas affected: medial temporal lobes. Patient 2: frontotemporal lobar dementia, areas affected: frontal lobes.
After suffering a severe head injury, a patient demonstrates a dense anterograde amnesia. She
b. cannot remember events that occurred after the injury.
A patient visits a neurologist and complains of memory problems, such as trouble remembering telephone numbers. After a few tests, the neurologist determines that there is a large impairment in the digit span, but no impairment in remembering the past or in forming new memories. Which brain area is the most likely to be impaired?
c. the left perisylvian cortex
The memory performance of patients K.F. and E.E., when compared to the memory performance of people with amnesia, such as patient H.M, demonstrates a double dissociation between two types of memory. Which of the following statements best describes these results?
b. H.M. has a deficit limited to long-term memory, whereas K.F. and E.E. have deficits limited to short-term memory.
Research using the mismatch field (MMF), which is the magnetic equivalent of the mismatch negativity (MMN), has suggested that auditory sensory memory has a duration of about
d. 10 seconds.
George Miller and other investigators found that humans can hold about ________ items in short-term memory at a time.
c. seven
Organizing individual bits of information into higher-order units can increase the amount of information that can be held in short-term memory. This strategy is called
d. chunking.
According to the modal model of memory, information that is currently held within short-term memory originates from
a. sensory memory.
Which of the following best describes the flow of information in the Atkinson and Shiffrin (1968) modal model of memory?
c. sensory memory ® short-term storage ® long-term storage
Which of the following statements concerning types of memory in the modal model of memory is FALSE?
b. Some contents of sensory memory are selected via attention and next processed in long-term memory.
You learn of an experiment conducted in 1942 by a researcher named Malmo. Malmo discovered that monkeys with certain lesions were impaired in a delayed-response task, but not when the lights were turned off. Malmo hypothesized that switching off the lights removed potential interference. Which of the following theories incorporates this kind of short-term interference?
d. the modal model of memory
The term ________ refers to a limited-capacity store that not only retains information over the short-term (maintenance) but also permits the performance of mental operations with the contents of this store (manipulation).
a. working memory
One finding that supports the idea that information in working memory is represented by an acoustic (auditory) code rather than a semantic (meaning-based) code is that when participants are given a list of words to learn and then are immediately tested for recall, performance is ______ when the list contains items that are similar in _______.
c. worse; sound
Of the following choices, damage to the ________ is most likely to result in impairment to the visuospatial sketch pad, or visual working memory.
a. parietal–occipital cortex
Visual sensory memory is to ________ as auditory sensory memory is to ________.
a. iconic memory; echoic memory
One major difference between the visual icon and the auditory echo is that the
b. auditory echo lasts longer than the visual icon.
One property of the central executive mechanism proposed by Baddeley and Hitch is that it
b. is not linked to a single modality.
The component that is responsible for acoustically coding information in working memory is the
c. phonological loop.
Declarative or explicit memory is knowledge that
a. one can access consciously.
Barbara remembers that Madrid is the capital of Spain, but she has no idea when or where she acquired this knowledge. Her ________ memory is accurate, but her ________ memory is incomplete.
a. semantic; episodic
Classical conditioning is an example of a specific type of ________ memory.
d. nondeclarative
________ memory does NOT affect behavior consciously.
a. Nondeclarative
In the delayed nonmatching to sample task, animals are taught in a single trial that a specific object is associated with a food reward. When this object is shown again in a subsequent trial in the presence of a new object, the animal
b. must select the new item to receive a food reward.
Patient H.M. is to the ________ as patients with Korsakoff’s syndrome are to the ________.
d. medial temporal lobes; diencephalon
It appears that the medial temporal lobes and the diencephalon are important in consolidating explicit long-term memories but are not themselves the storage sites for this knowledge because
d. most episodic and semantic memories acquired before injury to these structures will remain intact.
Two weeks ago, you saw a patient who was suffering from amnesia, and the amnesia appeared to be related to the vertebrobasilar artery system. Currently, the patient’s memory seems to have returned to normal. Which of the following people is most likely to be the patient described?
d. A 59-year-old grocery store owner who works long hours and is struggling financially.
Following a case of encephalitis, a person has developed lesions in his anterior temporal lobes, but his medial temporal structures are intact. Which of the following is most likely to be true of this person?
b. The person has isolated retrograde amnesia.
After a brain injury, a person is found to have isolated retrograde amnesia. Which of the following brain regions is probably damaged?
b. the anterior temporal lobes
Greater activity in the frontal and parietal portions of the retrieval network is to __________ as greater activity in the medial temporal lobe and sensory areas is to __________.
a. false memories; true memories
Neuroimaging work has suggested that during the retrieval of a list of studied items, the hippocampus is most active
a. for items that are correctly recollected as old items.
Recent neuroimaging and neuropsychological work in memory has attempted to disentangle ________, which seems to implicate the hippocampus and the posterior parahippocampal cortex, from ________, which seems to implicate the perirhinal cortex.
c. recollection; familiarity
Neuroimaging studies of the left and right hemispheres in memory function indicate that
b. encoding and retrieval processes in long-term memory may be lateralized to different hemispheres.
When individuals encode information that relates to themselves, which of following regions is particularly likely to be active?
c. retrosplenial cortex
Consider the binding-of-items-and-contexts (BIC) model. The perirhinal cortex is to the parahippocampal cortex as __________ is to __________.
c. who and what; when and where
Under the standard consolidation theory, the involvement of the hippocampus in accessing memories is best described as
a. temporary.
Under the multiple trace theory, the neocortex is to semantic memory as the hippocampus is to
d. episodic memory.
Which of the following best describes a component of the multiple trace theory?
b. Episodic memory relies on the hippocampus for retrieval.
Herpes simplex encephalitis shares which characteristic with semantic dementia?
c. viral transmission
Hebbian learning occurs when
a. a synapse is strengthened by the synchronous activity of the presynaptic and postsynaptic neurons.
Long-term potentiation does NOT occur unless the neurotransmitter ________ is present in the synapse to bind to postsynaptic NMDA receptors.
d. glutamate
Imagine that a new drug is discovered that acts by depleting the brain of free magnesium ions. How would this drug affect long-term potentiation (LTP)?
a. The amount of LTP would increase.
Which of the following statements is true regarding the role of NMDA receptors in mediating LTP in the brain?
a. NMDA receptors are critical to inducing LTP but not to maintaining LTP.
Patients with damage to the medial temporal lobe and hippocampus typically do not have difficulty performing short-term memory tasks such as the digit span.
True
Patient H.M. had severe retrograde amnesia.
False
People with amnesia often show preserved implicit learning and nondeclarative memory.
True
In the Atkinson and Shiffrin modal model, information can be lost by both decay and interference at each stage.
True
Semantic memory is a kind of declarative memory that concerns events we recall from our own lives.
False
Most forms of classical conditioning can be considered declarative memory.
False
Lesions to the hippocampus typically do not result in profound memory problems unless the lesions also encompass the amygdala.
False
Korsakoff’s syndrome is associated with alcoholism.
True
During memory retrieval, cortical regions that were important during encoding are reactivated.
True
Dopamine is the neurotransmitter most associated with long-term potentiation.
False
Which of the following is NOT considered a characteristic of emotions?
b. similarity to moods
Emotions are ________ responses to external or internal stimuli.
d. valenced
Which of the following is NOT considered one of the six basic facial expressions representing emotional states?
b. jealousy
Which of the following statements best describes the distinction between affect, mood, and emotion?
a. Affect is the most general term of the three, and it includes emotions, which tend to be short-term and reactionary; moods tend to last longer than emotions.
One theory of emotion and the brain from the mid 20th century implicated the hypothalamus, anterior thalamus, cingulate gyrus, and hippocampus. These structures were later named the ________ circuit.
d. Papez
Which of the following is NOT a well-established basic emotion?
c. contempt
A patient reports feeling intense sadness. Which of the following signs would indicate that this is true?
a. facial expression
b. physiological reaction
c. brief duration
d. All of the answer options are correct.
D IS THE CORRECT ANSWER
Which of the following best describes our current understanding of the brain areas that process emotions?
b. The limbic system seems to be heavily involved in processing emotion, with contribution from other brain areas, particularly in frontal-medial cortical areas.
Which of the following outcomes is MOST likely to be produced by the information gleaned from studies using multivoxel pattern analysis (MVPA) and 7-tesla scanning (7T) technology to better elucidate the neural structures associated with different emotional states?
d. Each emotion is processed by a network of brain regions, some of which overlap with many other emotions, and some of which overlap with few or no other emotions.
Some theories of emotion employ a factor approach. In one conceptualization, the first factor is ________, or how pleasant or unpleasant the stimulus is, and the second factor is ________, or how intense the emotional response is.
b. valence; arousal
In one conceptualization of emotions (Davidson et al. 1990), some emotional states such as happiness and surprise create a tendency to ________, whereas other emotional states such as fear and disgust create a tendency to ________.
a. approach; withdraw
Which of the following would be MOST useful in establishing discrete categories of emotions?
b. A better understanding of which overlapping networks of brain regions process which emotions.
Which of the following, in itself, would be expected to have the LEAST effect on individual differences in emotional processing of a particular stimulus?
d. Differences in the gender of individuals processing the stimulus.
Julian spots a snake in the forest. He immediately runs away from it and then notes that he is scared as he is running. Which of the following theories would suggest that his feeling of fear is due entirely to the fact that Julian notices his physiological response?
a. James–Lange theory
Klüver–Bucy syndrome is associated with damage to which brain structure or region?
c. the amygdala
The ________ is a small, almond-shaped structure in the medial temporal lobe, immediately adjacent to the anterior portion of the ________.
d. amygdala; hippocampus
The amygdala consists of several subnuclei. During fear conditioning, information converges on the ________ of the amygdala and from there projects to the ________.
a. lateral nucleus; central nucleus
Fear conditioning is a more specific instance of
a. classical conditioning.
One of the two pathways of the amygdala is known as the “low road.” This pathway can be characterized as ________ and involves a ________.
c. “quick and dirty”; direct signal from the thalamus to the amygdala
One of the two pathways of the amygdala is known as the “high road.” This pathway can be characterized as _________ and involves a ________.
b. “slow and analytical”; project to the cortex
A double dissociation has been demonstrated between people with damage to the ________, who show impairment in the explicit or declarative aspects of fear conditioning, and people with damage to the ________, who show impairment in the implicit or nondeclarative aspects of fear conditioning
b. hippocampus; amygdala
Which of the following results best supports the notion that the amygdala modulates the consolidation of hippocampus-based memories?
d. Modulation of hippocampus-based learning by arousal occurs after the initial encoding of the task, during retention.
The mechanism through which the amygdala modulates hippocampus-based learning may be related to the observation that
a. arousing stimuli decay less quickly than nonarousing stimuli do.
You conduct an experiment in which you expose a rat repeatedly to a 440 Hz tone and an electric shock. After a few trials, the rat begins to show signs of fear in response to the tone. In this paradigm, the electric shock is the ________, while the tone is the ________.
b. unconditioned stimulus; conditioned stimulus
Lesions to the amygdala ________ unconditioned responses to aversive events, ________ the ability to acquire and express a conditioned response to neutral stimuli.
b. do not block; but they do block
Patient S.P., who had bilateral damage to the amygdala, participated in a study involving the pairing of a blue square with an electric shock. S.P.’s skin conductance response (SCR) and verbal report indicated that
b. she had an explicit expectation that the shock would occur after seeing the blue square but did not demonstrate any implicit fear-conditioning SCR response.
Which of the following is true about the role of the amygdala in explicit emotional learning?
a. The amygdala performs a modulatory role in declarative memory.
In a fear-conditioning experiment, you find a person who shows a normal skin conductance response to a conditioned stimulus (such as a blue square) but who does not consciously remember the pairing of the conditioned stimulus with the unconditioned stimulus (such as a shock). This person may have damage to the
b. hippocampus.
Which of the following is a way in which the amygdala interacts with hippocampus-dependent memories?
d. enhancing the strength of explicit or declarative memories for emotional events
Which of the following is true regarding the amygdala and emotional learning?
a. The amygdala plays a role in the expression of fear responses, regardless of whether the initial learning was implicit or explicit.
A rat’s performance on the Morris water maze, a test of spatial ability and memory, will be affected in what way by a lesion to the amygdala?
b. The rat will not be impaired in a basic water maze task, but it will fail to show the stronger retention that would otherwise be expected if the task includes a physical stressor
Neuroimaging of the perception of facial expression suggests that
d. the amygdala responds most strongly to fearful faces, but it also shows some response to other expressions
The amygdala responds to fearful facial expressions
a. regardless of whether the face is consciously perceived.
Which of the following is typically true of people with bilateral damage to the amygdala?
b. They are like controls in their implicit and explicit reactions to race