exam 2 Flashcards

(39 cards)

1
Q

SSRI’s treat depression by:

A

blocking the reuptake of serotnon

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2
Q

The ___ produces neurohormones, whereas the ____ secretes releasing hormones

A

hypothalamus;

pituitary gland

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3
Q

____ is the substance that enhances neurotransmitter function, whereas ___ is the substance that blocks neurotransmitter function

A

agonist;

antagonist

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4
Q

A variety of drugs that are used to treat epilepsy are also effective in treating:

A

The manic phase of bipolar disorder

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5
Q

Epinephrine…

A

activates the endocrine glands and the brain in response to stress

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6
Q

Which of the following drugs has a higher concordance rate for addiction in identical twins?

A

alcohol

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7
Q

____ results when brain cell activities adjust to minimize the effects of the drug in the blood.

A

Cellular tolerance

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8
Q

___ is linked with shaking in the limbs, loss of balance, and general loss of muscular control.

A

Parkinson’s disease

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9
Q

all neurons leaving the spinal cord have:

A

acetylcholine as a neurotransmitter

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10
Q

type 1 synapses are found on the ____. while type 2 synapses are found on the ____.

A

Spines or dendritic shafts of the neuron;

neuron cell body

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11
Q

____ contain the neurotransmitters

A

synaptic vesicles

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12
Q

serotonin has been related to:

A

depression

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13
Q

another term for volts is:

A

electrical potential between two poles

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14
Q

The neurotransmitter-sensitive ion channels on muscle end plates differ from other ion channels in that:

A

K+ and Na+ enter and leave through the same channels

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15
Q

A change in the resting potential from -70 mV to -65 mV is called:

A

depolarization

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16
Q

Because of refractory periods, the maximum firing rate of a neuron is approximately:

A

200 impulses per second

17
Q

The negative charge inside of the cell membrane is largely a product of the presence of:

A

negatively charged protein anions

18
Q

Galvani discovered…

A

that the muscles of dead frogs legs twitched when struck by electricity

19
Q

conclusion of early electrical recording studies

A

flow of information in the nervous system is too slow to be a flow of electricity.

nerve conduction: 30-40 meters/sec
electricity in wire: ≈ 300 million meters/sec

20
Q

electrographic seizures:

A

abnormal rhythmic neuronal discharges; may be recorded by an electroencephalogram

21
Q

electrical stimulation

A

passage of an electrical current from the uninsulated tip of an electrode through tissue

22
Q

synthesis of a neurotransmitter can take place in..

A

the cell body, the axon, or the terminal

23
Q

storage of the neurotransmitter is in…

A

granules or vesicles or both

24
Q

release of a transmitter is from the..

A

terminal’s presynaptic membrane into the synapse

25
receptor interaction takes place in…
the postsynaptic membrane, as the transmitter acts on an embedded receptor
26
inactivation of excess neurotransmitter occurs at…
the synapse
27
two outcomes of drug action
1) reuptake into the presynaptic terminal for reuse | 2) degradation of excess neurotransmitter by synaptic mechanisms & removal of unneeded by-products from the synapse.
28
agonists
drugs that increase neurotransmission
29
antagonists
drugs that decrease neurotransmission
30
metabolic tolerance
the number of enzymes needed to break down alcohol in the liver, blood, and brain increases
31
cellular tolerance
brain cell activities adjust to minimize the effects of alcohol in the blood. (behavioral signs are low with high alcohol level)
32
learned tolerance
drop in outward signs of intoxication. people learn to not look drunk
33
antianxiety agent
drug that reduces anxiety. ex: benzos, sedative-hypnotic agents
34
barbiturate
drug that produces sedation and sleep
35
cross-tolerance
reduction of response to a novel drug because of tolerance to a chemically related drug
36
dopamine hypothesis of schizophrenia
idea that excess dopamine activity causes symptoms of schizophrenia
37
tricyclic antidepressant
first-gen antidepressant; its chemical structure characterized by 3 rings, blocks 5-HT reuptake
38
second-gen anti depressants
also called atypical antidepressants
39
selective serotonin reuptake inhibitor (SSRI)
drug that blocks 5-HT reuptake into presynaptic terminal