Exam 2 Flashcards
what does connective tissue develop from
mesenchyme (which develops from mesoderm)
basic components of connective tissue
specialized cells
ECM
components of ECM
proteins + ground substance
functions of connective tissue
structure transport protection support store energy immune support
broad categories of connective tissue
connective tissue proper
fluid connective tissue
supporting connective tissue
connective tissue proper types
loose and dense
fluid connective tissue types
blood and lymph
supporting connective tissue types
cartilage and bone
fibers of connective tissue
collagen
reticular
elastic
collagen
long, straight, unbranched, strong
tendons and ligaments
reticular
branched, interwoven, flexible
elastic
branched, wavy, extensible
cells of connective tissue proper
fibroblasts adipocytes macrophages melanocytes mast cells lymphocytes
fibroblasts
present in all connective tissue
give rise to other cells
secrete ECM
adipocytes
fat cells
empty (signate) appearance on slides
macrophages
phagocytes for pathogens or dead tissue
can be fixed or free
melanocytes
synthesize melanin
mast cells
stimulate local inflammation via vesicles containing histamine
lymphocytes
T cells
B cells
NK cells
plasma cells
B cells that have begun producing antibodies
types of loose connective tissue proper
mucous
areolar
adipose
reticular
mucous connective tissue
embryonic tissue
found in umbilical cord
adipose tissue
white or brown
reticular tissue
found in spleen and liver
dense connective tissue types
regular - found in tendons and ligaments
irregular - found in organ capsules
cartilage
avascular tissue
set apart from other tissues by perichondrium
perichondrium layers
outer fibrous layer
inner cellular layer
cartilage growth
interstitial (added to inside)
appositional (added to outside)
types of cartilage
hyaline
elastic
fibro
hyaline cartilage function and location
to be tough and somewhat flexible
articular cartilage
elastic cartilage function and location
to be resilient and flexible
pinna of outer ear, auditory tube
fibrocartilage function and location
resist compression
discs and menisci
NOT COVERED BY PERICHONDRIUM
classifications of bones + 1 example of each
long (femur) short (carpals) flat (sternum) irregular (vertebra) sesamoid (patella) sutural (skull sutures)
components of a flat bone
2 layers of compact bone with a spongy layer in the middle called the diploe
bone tissue types
compact (or dense)
spongy (or cancellous)
what accounts for the weight of bone
2/3 calcium phosphate
1/3 collagen
cells in bone tissue
osteocytes
osteoblasts
osteoclasts
osteoprogenitor cells
osteocytes
mature bone cells
do not divide
osteoblasts
secrete osteoid
osteoclasts
resorption of bone matrix
not osteogenic in origin
ossification definition
replacement of other tissue types with bone tissue
types of ossification
intramembranous
endochondral
intramembranous ossification
mesenchyme to bone
occurs in clavicle, sternum, cranial flat bones
endochondral ossification
cartilage to bone
long bones
steps of endochondral ossification
chondrocytes enlarge and die
blood vessels penetrate perichondrium
inner cell layer differentiates into osteoblasts
osteoblasts secrete bone matrix - spongy bone forms 1st
osteoclasts/osteoblasts go back and forth to create marrow cavity and compact bone
closure
completion of epiphyseal growth
appositional growth
increase in diameter from outer surface
interstitial growth
increase in length from inner surface
embryonic growth
vitamin D and bone effect
vitamin D activated by sun, goes to liver to become calcidiol, goes to kidney to become calcitriol
increases calcium phosphate absorption and reabsorption
vitamin D deficiency
rickets
vitamin C and effect on bone
collagen synthesis
vitamin C deficiency
scurvy
vitamin A effect on bone
osteoblast activity
vitamin K effect on bone
synthesis of bone proteins
hormones that affect bone composition
parathyroid hormone
calcitonin
estrogen
parathyroid hormone
increases blood calcium levels by stimulating osteoclasts
calcitonin
decreases blood calcium levels by inhibiting osteoclasts
estrogen
stimulates osteoblasts