Exam 1_Grad Students_Stem cells and stuff

Question 1

totipotent stem cells

Answer 1

differentiate into any cell in the body

Question 2

Pluripotent stem cells

Answer 2

obtained from inner cell mass of the blastocyst or by dedifferntating cell; can differentiate into any cell body except cells of placenta

Question 3

multipotent stem cells

Answer 3

limited in cell lineages they can be

Question 4

why are stem cell important?

Answer 4

treatment potential

Question 5

Properties of stem cells

Answer 5

capable of dividing and renewing themselves for longer period

unspecialized- no function

can give rise to specialized cell types

Question 6

Endogenous neural stem cells in adult brain

Answer 6

subgraular zone of dentate gyrus

subventricular zone of lateral ventricles

Question 7

What determines which cells they differentiate into?

Answer 7

micro environment, chemical signals

Question 8

What are 3 big problems with stem cell implantation?

Answer 8

1) migration and transplanted cells
2) integration into circuitry
3) microenvironment of adult brain promotes gliogenesis