exam Flashcards
(44 cards)
the pacemaker potential occurs during
diastole
diastole
relaxation/resting peroid of heart
diastole
relaxation/resting period of heart
systole
contraction of the heart
- SA node (pacemaker)
- AV node
- bundle of His
- R & L bundle branches
- Purkinjie fibers
conduction system of the heart
- pacemaker of the heart
-sends signals to AV
-located in R atrium near the superior vena cava
-parasympathetic & sympathetic
SA node
pacemaker potential
slow, spontaneous depolarization
SA nodes do not have
a maintained RMP
- Resting membrane Potential = -85mV
-long phase (slow) (200-300ms)
-plateau phase - no summation or tetanus
Myocardial action potential
Source of calcium in muscle
- sarcoplasmic reticulum
- extracellular fluid
sarcoplasmic reticulum
stores calcium in muscle cells
- fast
- all Ca2+ comes from the sarcoplasmic reticulum
-somatic (voluntary) - striated, nuclei pushed to edges
skeletal
-Ca2+ comes from the sarcoplasmic reticulum and out of the cell
-autonomic (involuntary)
-striated, nuclei scattered, intercalated disks, branching
cardiac muscle
-almost all Ca2+ comes extracellular
-autonomic (involuntary) (slowest)
smooth muscle
Main differences between skeletal and cardiac muscle
cardiac branches and has intercalated disks (gap junction)
HCN channels
open in response to hyperpolarization
HCN channels (broken down)
H: hyperpolarization
CN: cyclic nucleotide (AMP)
threshold in heart
-40mV
once the heart reached the threshold…..
opens voltage regulated Ca2+ channels
calcium induced
calcium released
calcium from sarcoplasmic reticulum
causes muscle contractions
repolarization occurs (in heart)
with the opening of voltage-gated potassium channels
plateau phase
caused by slow calcium channels
potassium gives plateau
correlated to S-T segment
summation or tetanus is prevented by?
long refractory period